Macrophages support pathological erythropoiesis in polycythemia vera and β-thalassemia (Q36745518)

16 August 2017

Macrophages support pathological erythropoiesis in polycythemia vera and β-thalassemia (English)

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16 August 2017

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15

Patricia J Giardina

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16 August 2017

Pedro Ramos

1

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16 August 2017

Carla Casu

2

1 reference

16 August 2017

Sara Gardenghi

3

1 reference

16 August 2017

Laura Breda

4

1 reference

16 August 2017

Bart J Crielaard

5

1 reference

16 August 2017

Ella Guy

6

1 reference

16 August 2017

Maria Franca Marongiu

7

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16 August 2017

Ritama Gupta

8

1 reference

16 August 2017

Ross L Levine

9

1 reference

16 August 2017

Omar Abdel-Wahab

10

1 reference

16 August 2017

Benjamin L Ebert

11

1 reference

16 August 2017

Nico Van Rooijen

12

1 reference

16 August 2017

Saghi Ghaffari

13

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16 August 2017

Robert W Grady

14

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16 August 2017

Stefano Rivella

16

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16 August 2017

language of work or name

English

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publication date

17 March 2013

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16 August 2017

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16 August 2017

19

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16 August 2017

437-445

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16 August 2017

4

1 reference

https://scigraph.springernature.com/pub.10.1038/nm.3126

16 August 2017

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cites work

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β-thalassemia: a model for elucidating the dynamic regulation of ineffective erythropoiesis and iron metabolism

29 September 2017

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Evidence for distinct pathways of hepcidin regulation by acute and chronic iron loading in mice

29 September 2017

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Stress erythropoiesis: new signals and new stress progenitor cells

29 September 2017

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Bone marrow CD169+ macrophages promote the retention of hematopoietic stem and progenitor cells in the mesenchymal stem cell niche

29 September 2017

1 reference

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Hepcidin as a therapeutic tool to limit iron overload and improve anemia in β-thalassemic mice

29 September 2017

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JAK2 inhibitors: what's the true therapeutic potential?

29 September 2017

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Enhanced erythropoiesis in Hfe-KO mice indicates a role for Hfe in the modulation of erythroid iron homeostasis

29 September 2017

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Combinatorial and distinct roles of α₅ and α₄ integrins in stress erythropoiesis in mice

29 September 2017

1 reference

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Essential role for focal adhesion kinase in regulating stress hematopoiesis

29 September 2017

1 reference

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beta-Thalassemia: HiJAKing Ineffective Erythropoiesis and Iron Overload

29 September 2017

1 reference

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Therapeutic potential of JAK2 inhibitors

29 September 2017

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Erythropoiesis: model systems, molecular regulators, and developmental programs

29 September 2017

1 reference

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Ineffective erythropoiesis and thalassemias

29 September 2017

1 reference

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Trophic macrophages in development and disease

29 September 2017

1 reference

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Erythroblastic islands: niches for erythropoiesis

29 September 2017

1 reference

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Decreased differentiation of erythroid cells exacerbates ineffective erythropoiesis in beta-thalassemia

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618568

BMP4/Smad5 dependent stress erythropoiesis is required for the expansion of erythroid progenitors during fetal development

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618568

EPO receptor circuits for primary erythroblast survival

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618568

Role of Gas6 in erythropoiesis and anemia in mice

29 September 2017

1 reference

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Adherence to macrophages in erythroblastic islands enhances erythroblast proliferation and increases erythrocyte production by a different mechanism than erythropoietin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618568

TG101209, a small molecule JAK2-selective kinase inhibitor potently inhibits myeloproliferative disorder-associated JAK2V617F and MPLW515L/K mutations

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618568

Molecular insights into stress erythropoiesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618568

Ineffective erythropoiesis in beta-thalassemia is characterized by increased iron absorption mediated by down-regulation of hepcidin and up-regulation of ferroportin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618568

Enhanced natural-killer cell and erythropoietic activities in VEGF-A-overexpressing mice delay F-MuLV-induced erythroleukemia

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618568

Absence of erythroblast macrophage protein (Emp) leads to failure of erythroblast nuclear extrusion

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618568

Erythropoietin-dependent erythropoiesis: New insights and questions

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618568

A unique role for Stat5 in recovery from acute anemia

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618568

A gain-of-function mutation of JAK2 in myeloproliferative disorders

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618568

Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618568

A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618568

Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders

29 September 2017

1 reference

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Turning cells red: signal transduction mediated by erythropoietin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618568

BMP4 and Madh5 regulate the erythroid response to acute anemia

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618568

Loss of alpha-hemoglobin-stabilizing protein impairs erythropoiesis and exacerbates beta-thalassemia

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618568

Liposome mediated depletion of macrophages: mechanism of action, preparation of liposomes and applications

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618568

Mouse model of human beta zero thalassemia: targeted deletion of the mouse beta maj- and beta min-globin genes in embryonic stem cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618568

The role of membrane skeletal-associated alpha-globin in the pathophysiology of beta-thalassemia

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618568

Interaction of the erythropoietin and stem-cell-factor receptors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618568

Physiological Jak2V617F expression causes a lethal myeloproliferative neoplasm with differential effects on hematopoietic stem and progenitor cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618568

The macrophage CD163 surface glycoprotein is an erythroblast adhesion receptor

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618568

The splenic microenvironment is a source of proangiogenesis/inflammatory mediators accelerating the expansion of murine erythroleukemic cells

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618568

Erythropoietin stimulates spleen BMP4-dependent stress erythropoiesis and partially corrects anemia in a mouse model of generalized inflammation.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618568

Transferrin therapy ameliorates disease in beta-thalassemic mice.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618568

Ratio of mutant JAK2-V617F to wild-type Jak2 determines the MPD phenotypes in transgenic mice.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618568

Disruption of palladin leads to defects in definitive erythropoiesis by interfering with erythroblastic island formation in mouse fetal liver.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618568

Signals for stress erythropoiesis are integrated via an erythropoietin receptor-phosphotyrosine-343-Stat5 axis

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618568

Phosphatidylserine-dependent engulfment by macrophages of nuclei from erythroid precursor cells

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618568

Aging of red blood cells and impaired erythropoiesis following prolonged administration of dichloromethylene diphosphonate containing liposomes in rats

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618568

VEGF-A165 augments erythropoietic development from human embryonic stem cells

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618568

Changes in murine bone marrow macrophages and erythroid burst-forming cells following the intravenous injection of liposome-encapsulated dichloromethylene diphosphonate (Cl2MDP).

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618568

Insulin and insulin-like growth factor I support the proliferation of erythroid progenitor cells in bone marrow through the sharing of receptors.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618568

Very late activation antigen 4-vascular cell adhesion molecule 1 interaction is involved in the formation of erythroblastic islands

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618568

Two to tango: regulation of Mammalian iron metabolism

5 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNM.3126

Targeted disruption of the hepcidin 1 gene results in severe hemochromatosis

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNM.3126

Impaired splenic erythropoiesis in phlebotomized mice injected with CL2MDP-liposome: an experimental model for studying the role of stromal macrophages in erythropoiesis

21 January 2018

1 reference

12 December 2020

Myeloproliferative disorders

1 reference

12 December 2020

Transgenic mice with hematopoietic and lymphoid specific expression of Cre

1 reference

12 December 2020

[Erythroblastic island, functional unity of bone marrow]

1 reference

12 December 2020

Role of the reticular cells during maturation process of the erythroblast. 3. The fate of phagocytized nucleus

1 reference

12 December 2020

The association of erythroblasts with macrophages promotes erythroid proliferation and maturation: a 30-kD heparin-binding protein is involved in this contact

1 reference

12 December 2020

Identifiers

DOI

10.1038/NM.3126

1 reference

Dimensions Publication ID

16 August 2017

1021521761

0 references

Fatcat ID

release_txnfwd4mrfajhc6o53a5w4sxn4

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/txnfwd4mrfajhc6o53a5w4sxn4

24 November 2022

mapped directly with Wikidata item

1 reference

16 August 2017

1 reference