Activator protein-2 in carcinogenesis with a special reference to breast cancer--a mini review (Q36748207)

16 August 2017

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title

Activator protein-2 in carcinogenesis with a special reference to breast cancer--a mini review (English)

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16 August 2017

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2

Veli-Matti Kosma

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author name string

Johanna M Pellikainen

series ordinal

1

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PubMed ID

17330235

16 August 2017

language of work or name

English

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publication date

1 May 2007

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International Journal of Cancer

16 August 2017

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16 August 2017

120

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16 August 2017

10

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16 August 2017

2061-2067

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Positive and negative regulation of transcription in vitro: enhancer-binding protein AP-2 is inhibited by SV40 T antigen

16 August 2017

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Cloning and expression of AP-2, a cell-type-specific transcription factor that activates inducible enhancer elements

21 January 2018

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Transcription factor AP-2 mediates induction by two different signal-transduction pathways: protein kinase C and cAMP.

21 January 2018

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Regulation of transcription factor AP-2 by the morphogen retinoic acid and by second messengers.

21 January 2018

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Cloning and characterization of a novel human transcription factor AP-2 beta like gene (TFAP2BL1).

21 January 2018

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AP-2.2: a novel AP-2-related transcription factor induced by retinoic acid during differentiation of P19 embryonal carcinoma cells.

21 January 2018

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Localization of the gene for the DNA-binding protein AP-2 to human chromosome 6p22.3-pter

21 January 2018

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Chromosomal mapping of the human and mouse homologues of two new members of the AP-2 family of transcription factors

21 January 2018

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Cloning and characterization of a novel mouse AP-2 transcription factor, AP-2delta, with unique DNA binding and transactivation properties

21 January 2018

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Cloning and characterization of the mouse AP-2 epsilon gene: a novel family member expressed in the developing olfactory bulb

21 January 2018

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Identification and embryonic expression of a new AP-2 transcription factor, AP-2 epsilon

21 January 2018

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The AP-2 family of transcription factors

21 January 2018

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Regulatory roles of AP-2 transcription factors in vertebrate development, apoptosis and cell-cycle control

21 January 2018

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AP2 inhibits cancer cell growth and activates p21WAF1/CIP1 expression

21 January 2018

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Identification of ERF-1 as a member of the AP2 transcription factor family

21 January 2018

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The developmentally regulated transcription factor AP-2 is involved in c-erbB-2 overexpression in human mammary carcinoma

21 January 2018

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AP2alpha and AP2gamma: a comparison of binding site specificity and trans-activation of the estrogen receptor promoter and single site promoter constructs.

21 January 2018

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YY1 as a regulator of replication-dependent hamster histone H3.2 promoter and an interactive partner of AP-2.

21 January 2018

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A synergistic interaction of transcription factors AP2 and YB-1 regulates gelatinase A enhancer-dependent transcription

21 January 2018

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Tumor suppressor activity of AP2alpha mediated through a direct interaction with p53.

21 January 2018

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RB and c-Myc activate expression of the E-cadherin gene in epithelial cells through interaction with transcription factor AP-2.

21 January 2018

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Transcription Factors Pax6 and AP-2alpha Interact To Coordinate Corneal Epithelial Repair by Controlling Expression of Matrix Metalloproteinase Gelatinase B

21 January 2018

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Repression of a matrix metalloprotease gene by E1A correlates with its ability to bind to cell type-specific transcription factor AP-2.

21 January 2018

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Physical and functional interactions between the Wwox tumor suppressor protein and the AP-2gamma transcription factor

21 January 2018

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GAS41 interacts with transcription factor AP-2beta and stimulates AP-2beta-mediated transactivation

21 January 2018

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PolyADP-ribose polymerase is a coactivator for AP-2-mediated transcriptional activation.

21 January 2018

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Activator protein 2alpha associates with adenomatous polyposis coli/beta-catenin and Inhibits beta-catenin/T-cell factor transcriptional activity in colorectal cancer cells

21 January 2018

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Physical and functional interactions among AP-2 transcription factors, p300/CREB-binding protein, and CITED2

21 January 2018

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Human CREB-binding protein/p300-interacting transactivator with ED-rich tail (CITED) 4, a new member of the CITED family, functions as a co-activator for transcription factor AP-2

21 January 2018

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Coactivator PC4 mediates AP-2 transcriptional activity and suppresses ras-induced transformation dependent on AP-2 transcriptional interference

21 January 2018

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Transcriptional activation by AP-2alpha is modulated by the oncogene DEK

21 January 2018

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A WW domain-containing yes-associated protein (YAP) is a novel transcriptional co-activator

21 January 2018

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Transcription factor AP-2 activity is modulated by protein kinase A-mediated phosphorylation.

21 January 2018

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Transcription factor AP-2 interacts with the SUMO-conjugating enzyme UBC9 and is sumolated in vivo

21 January 2018

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Activator protein 2alpha inhibits tumorigenicity and represses vascular endothelial growth factor transcription in prostate cancer cells

21 January 2018

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Overexpression of transcription factor AP-2alpha suppresses mammary gland growth and morphogenesis.

21 January 2018

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AP-2-null cells disrupt morphogenesis of the eye, face, and limbs in chimeric mice

21 January 2018

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Transcription factor AP-2 essential for cranial closure and craniofacial development

21 January 2018

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Neural tube, skeletal and body wall defects in mice lacking transcription factor AP-2

21 January 2018

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Terminal renal failure in mice lacking transcription factor AP-2 beta

21 January 2018

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Enhanced apoptotic cell death of renal epithelial cells in mice lacking transcription factor AP-2beta

21 January 2018

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Mutations in TFAP2B cause Char syndrome, a familial form of patent ductus arteriosus

21 January 2018

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Transcription factor gene AP-2 gamma essential for early murine development

21 January 2018

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Gene regulation in melanoma progression by the AP-2 transcription factor

21 January 2018

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Loss of AP-2 results in downregulation of c-KIT and enhancement of melanoma tumorigenicity and metastasis.

21 January 2018

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Loss of AP-2 results in up-regulation of MCAM/MUC18 and an increase in tumor growth and metastasis of human melanoma cells.

21 January 2018

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Loss of activator protein-2alpha results in overexpression of protease-activated receptor-1 and correlates with the malignant phenotype of human melanoma

21 January 2018

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Suppression of invasion and peritoneal carcinomatosis of ovarian cancer cells by overexpression of AP-2alpha

21 January 2018

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The AP-2gamma transcription factor is upregulated in advanced-stage ovarian carcinoma.

21 January 2018

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Expression of transcription factor AP-2 in colorectal adenomas and adenocarcinomas; comparison of immunohistochemistry and in situ hybridisation

21 January 2018

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p22/WAF1 expression in human colorectal carcinoma: association with p53, transcription factor AP-2 and prognosis

21 January 2018

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Transcription factor AP-2gamma is a developmentally regulated marker of testicular carcinoma in situ and germ cell tumors.

21 January 2018

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Transcription factor AP-2gamma, a novel marker of gonocytes and seminomatous germ cell tumors.

21 January 2018

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Differential expression of activator protein-2 isoforms in renal cell carcinoma

21 January 2018

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Different properties of three isoforms (alpha, beta, and gamma) of transcription factor AP-2 in the expression of human keratinocyte genes.

21 January 2018

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Immunohistochemical analysis reveals a tumour suppressor-like role for the transcription factor AP-2 in invasive breast cancer

21 January 2018

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The human transcription factor activation protein-2 gamma (AP-2gamma): gene structure, promoter, and expression in mammary carcinoma cell lines.

21 January 2018

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Automated quantitative analysis of activator protein-2alpha subcellular expression in melanoma tissue microarrays correlates with survival prediction

21 January 2018

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Redistribution of transcription factor AP-2alpha in differentiating cultured human epidermal cells

21 January 2018

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Differential expression of AP-2gamma and AP-2alpha during human trophoblast differentiation.

21 January 2018

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A subtractive gene expression screen suggests a role of transcription factor AP-2 alpha in control of proliferation and differentiation

21 January 2018

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Cell cycle arrest and apoptosis induction by activator protein 2alpha (AP-2alpha) and the role of p53 and p21WAF1/CIP1 in AP-2alpha-mediated growth inhibition

21 January 2018

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p21WAF1 expression in invasive breast cancer and its association with p53, AP-2, cell proliferation, and prognosis

21 January 2018

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Activator protein 2alpha status determines the chemosensitivity of cancer cells: implications in cancer chemotherapy

21 January 2018

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Transcription factor AP-2alpha is preferentially cleaved by caspase 6 and degraded by proteasome during tumor necrosis factor alpha-induced apoptosis in breast cancer cells

21 January 2018

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The retinoblastoma protein binds the promoter of the survival gene bcl-2 and regulates its transcription in epithelial cells through transcription factor AP-2.

21 January 2018

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AP-2gamma induces p21 expression, arrests cell cycle, and inhibits the tumor growth of human carcinoma cells

21 January 2018

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Elevated expression levels of NCOA3, TOP1, and TFAP2C in breast tumors as predictors of poor prognosis.

21 January 2018

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Genomic structure of the promoters of the human estrogen receptor-alpha gene demonstrate changes in chromatin structure induced by AP2gamma

21 January 2018

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Transcriptional regulation of estrogen receptor in breast carcinomas

21 January 2018

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Activator protein-2gamma (AP-2gamma) expression is specifically induced by oestrogens through binding of the oestrogen receptor to a canonical element within the 5'-untranslated region

21 January 2018

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First-line, single-agent Herceptin(trastuzumab) in metastatic breast cancer: a preliminary report

21 January 2018

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Update on HER-2 as a target for cancer therapy: the ERBB2 promoter and its exploitation for cancer treatment

21 January 2018

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Dominant negative interference of transcription factor AP-2 causes inhibition of ErbB-3 expression and suppresses malignant cell growth

21 January 2018

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Identification of HTF (HER2 transcription factor) as an AP-2 (activator protein-2) transcription factor and contribution of the HTF binding site to ERBB2 gene overexpression

21 January 2018

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Distal ERBB2 promoter fragment displays specific transcriptional and nuclear binding activities in ERBB2 overexpressing breast cancer cells

21 January 2018

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Cofactor competition between the ligand-bound oestrogen receptor and an intron 1 enhancer leads to oestrogen repression of ERBB2 expression in breast cancer

21 January 2018

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Expression of HER2 and its association with AP-2 in breast cancer

21 January 2018

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Inefficient proteasomal-degradation pathway stabilizes AP-2alpha and activates HER-2/neu gene in breast cancer

21 January 2018

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Tumorigenic effect of transcription factor hAP-2alpha and the intricate link between hAP-2alpha activation and squelching.

21 January 2018

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Transcriptional activity of the human tissue inhibitor of metalloproteinases 1 (TIMP-1) gene in fibroblasts involves elements in the promoter, exon 1 and intron 1.

21 January 2018

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Expression of matrix metalloproteinase (MMP)-2 and MMP-9 in breast cancer with a special reference to activator protein-2, HER2, and prognosis

21 January 2018

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Distinct spatial expression patterns of AP-2alpha and AP-2gamma in non-neoplastic human breast and breast cancer

21 January 2018

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Dual role of AP-2? in ErbB-2-induced mammary tumorigenesis

21 January 2018

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Combination Analysis of Activator Protein-1 Family Members, Sp1 and an Activator Protein-2 -Related Factor Binding to Different Regions of the Urokinase Receptor Gene in Resected Colorectal Cancers

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/IJC.22648

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16 August 2017

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PubMed ID

17330235