Combination of radiotherapy with EGFR antagonists for head and neck carcinoma (Q36795322)

16 August 2017

1 reference

title

Combination of radiotherapy with EGFR antagonists for head and neck carcinoma (English)

1 reference

16 August 2017

1

Juliette Thariat

1 reference

16 August 2017

4

Adam S Garden

1 reference

16 August 2017

6

K Kian Ang

1 reference

16 August 2017

Gokcen Yildirim

2

1 reference

16 August 2017

Kathryn A Mason

series ordinal

3

1 reference

16 August 2017

Luka Milas

series ordinal

5

1 reference

16 August 2017

publication date

27 April 2007

1 reference

International Journal of Clinical Oncology

16 August 2017

published in

1 reference

16 August 2017

volume

12

1 reference

16 August 2017

issue

2

1 reference

16 August 2017

page(s)

99-110

1 reference

Radiation-induced release of transforming growth factor alpha activates the epidermal growth factor receptor and mitogen-activated protein kinase pathway in carcinoma cells, leading to increased proliferation and protection from radiation-induced ce

16 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1007%2FS10147-006-0663-5

Importance of maintenance therapy in C225-induced enhancement of tumor control by fractionated radiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10147-006-0663-5

Early phase I data on an irreversible pan-erb inhibitor: CI-1033. What did we learn?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10147-006-0663-5

Phase II data with ZD6474, a small-molecule kinase inhibitor of epidermal growth factor receptor and vascular endothelial growth factor receptor, in previously treated advanced non-small-cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10147-006-0663-5

Role of transactivation of the EGF receptor in signalling by G-protein-coupled receptors

21 January 2018

1 reference

12 December 2020

C225 antiepidermal growth factor receptor antibody enhances tumor radiocurability.

1 reference

12 December 2020

Mutant epidermal growth factor receptor (EGFRvIII) contributes to head and neck cancer growth and resistance to EGFR targeting

1 reference

12 December 2020

Dysregulation of epidermal growth factor receptor expression in premalignant lesions during head and neck tumorigenesis

1 reference

12 December 2020

Mechanisms of enhanced radiation response following epidermal growth factor receptor signaling inhibition by erlotinib (Tarceva).

1 reference

12 December 2020

Phosphorylation of Y845 on the epidermal growth factor receptor mediates binding to the mitochondrial protein cytochrome c oxidase subunit II.

1 reference

12 December 2020

The efficacy of ErbB receptor-targeted anticancer therapeutics is influenced by the availability of epidermal growth factor-related peptides.

1 reference

12 December 2020

Quantitative determination of nuclear and cytoplasmic epidermal growth factor receptor expression in oropharyngeal squamous cell cancer by using automated quantitative analysis

1 reference

12 December 2020

Multicenter phase II study of erlotinib, an oral epidermal growth factor receptor tyrosine kinase inhibitor, in patients with recurrent or metastatic squamous cell cancer of the head and neck

1 reference

12 December 2020

Small-molecule tyrosine kinase inhibitors as radiosensitizers

1 reference

12 December 2020

Administration of CI-1033, an irreversible pan-erbB tyrosine kinase inhibitor, is feasible on a 7-day on, 7-day off schedule: a phase I pharmacokinetic and food effect study

1 reference

12 December 2020

Radiation-induced epidermal growth factor receptor nuclear import is linked to activation of DNA-dependent protein kinase

1 reference

12 December 2020

Anti-epidermal growth factor receptor monoclonal antibodies may inhibit A431 tumor cell proliferation by blocking an autocrine pathway

1 reference

12 December 2020

Radiation-induced proliferation of the human A431 squamous carcinoma cells is dependent on EGFR tyrosine phosphorylation

1 reference

12 December 2020

Multicenter, randomized phase II trial of oral CI-1033 for previously treated advanced ovarian cancer

1 reference

12 December 2020

EGFR blockade with ZD1839 ("Iressa") potentiates the antitumor effects of single and multiple fractions of ionizing radiation in human A431 squamous cell carcinoma. Epidermal growth factor receptor

1 reference

12 December 2020

The stimulation of epidermal proliferation by a specific protein (EGF)

1 reference

12 December 2020

Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins

1 reference

12 December 2020

Epidermal growth factor receptor-stimulated activation of phospholipase Cgamma-1 promotes invasion of head and neck squamous cell carcinoma

1 reference

12 December 2020

Epidermal growth factor receptor blockade with C225 modulates proliferation, apoptosis, and radiosensitivity in squamous cell carcinomas of the head and neck.

1 reference

12 December 2020

Analysis of PTEN/MMAC1 alterations in aerodigestive tract tumors.

1 reference

12 December 2020

Epidermal growth factor receptor inhibition in cancer therapy: biology, rationale and preliminary clinical results

1 reference

12 December 2020

Nuclear localization of EGF receptor and its potential new role as a transcription factor

1 reference

12 December 2020

Comparative effects of neutrons and x-rays on mammalian cells

1 reference

12 December 2020

The hazard of accelerated tumor clonogen repopulation during radiotherapy

1 reference

12 December 2020

Low incidence of mutations in EGFR kinase domain in Caucasian patients with head and neck squamous cell carcinoma

1 reference

12 December 2020

ZD6474, a potent inhibitor of vascular endothelial growth factor signaling, combined with radiotherapy: schedule-dependent enhancement of antitumor activity.

1 reference

12 December 2020

Constitutive activation of Stat5b contributes to carcinogenesis in vivo

1 reference

12 December 2020

Relationship between cyclin D1 expression and poor radioresponse of murine carcinomas

1 reference

12 December 2020

Antitumor effects of ZD6474, a small molecule vascular endothelial growth factor receptor tyrosine kinase inhibitor, with additional activity against epidermal growth factor receptor tyrosine kinase.

1 reference

12 December 2020

Phosphatidylinositide 3-kinase/AKT in radiation responses

1 reference

12 December 2020

An open-and-shut case? Recent insights into the activation of EGF/ErbB receptors

1 reference

12 December 2020

Repopulation of cancer cells during therapy: an important cause of treatment failure

1 reference

12 December 2020

Epidermal growth factor receptor directed therapy in head and neck cancer

1 reference

12 December 2020

Heterodimerization of the erbB-1 and erbB-2 receptors in human breast carcinoma cells: a mechanism for receptor transregulation

1 reference

12 December 2020

VEGF-associated tyrosine kinase inhibition increases the tumor response to single and fractionated dose radiotherapy

1 reference

12 December 2020

The effect of ionizing radiation on signal transduction: antibodies to EGF receptor sensitize A431 cells to radiation

1 reference

12 December 2020

Clinical evaluation of ZD6474, an orally active inhibitor of VEGF and EGF receptor signaling, in patients with solid, malignant tumors

1 reference

12 December 2020

Prognostic value of epidermal growth factor receptor expression in patients with advanced stage nasopharyngeal carcinoma treated with induction chemotherapy and radiotherapy

1 reference

12 December 2020

Quantitative immunohistochemical analysis of transforming growth factor-alpha and epidermal growth factor receptor in patients with squamous cell carcinoma of the head and neck

1 reference

12 December 2020

Frequent genetic and biochemical alterations of the PI 3-K/AKT/PTEN pathway in head and neck squamous cell carcinoma

1 reference

12 December 2020

Multiple restriction fragment length polymorphisms of the human epidermal growth factor receptor gene.

1 reference

12 December 2020

Phase II trial of ZD1839 in recurrent or metastatic squamous cell carcinoma of the head and neck

1 reference

12 December 2020

Therapeutic potential of ABX-EGF: a fully human anti-epidermal growth factor receptor monoclonal antibody for cancer treatment

1 reference

12 December 2020

Use of the humanized anti-epidermal growth factor receptor monoclonal antibody h-R3 in combination with radiotherapy in the treatment of locally advanced head and neck cancer patients

1 reference

12 December 2020

Inhibition of apoptosis by amphiregulin via an insulin-like growth factor-1 receptor-dependent pathway in non-small cell lung cancer cell lines

1 reference

12 December 2020

Cancer statistics, 2006

1 reference

12 December 2020

The erbB family: targets for therapeutic development against cancer and therapeutic strategies using monoclonal antibodies and tyrosine kinase inhibitors

1 reference

12 December 2020

Combined modality therapy of A431 human epidermoid cancer using anti-EGFr antibody C225 and radiation

1 reference

12 December 2020

The epidermal growth factor receptor mediates radioresistance.

1 reference

12 December 2020

Radiation combined with EGFR signal inhibitors: head and neck cancer focus

1 reference

12 December 2020

Cetuximab shows activity in colorectal cancer patients with tumors that do not express the epidermal growth factor receptor by immunohistochemistry.

1 reference

12 December 2020

Phase II Multicenter Study of the Antiepidermal Growth Factor Receptor Monoclonal Antibody Cetuximab in Combination With Platinum-Based Chemotherapy in Patients With Platinum-Refractory Metastatic and/or Recurrent Squamous Cell Carcinoma of the Head

1 reference

12 December 2020

Nuclear EGFR signalling network in cancers: linking EGFR pathway to cell cycle progression, nitric oxide pathway and patient survival.

1 reference

12 December 2020

Src and Pyk2 mediate G-protein-coupled receptor activation of epidermal growth factor receptor (EGFR) but are not required for coupling to the mitogen-activated protein (MAP) kinase signaling cascade

1 reference

12 December 2020

Epidermal growth factor receptor biology in head and neck cancer

1 reference

12 December 2020

Epidermal growth factor-receptor-protein kinase interactions. Co-purification of receptor and epidermal growth factor-enhanced phosphorylation activity

1 reference

12 December 2020

Molecular inhibition of angiogenesis and metastatic potential in human squamous cell carcinomas after epidermal growth factor receptor blockade.

1 reference

12 December 2020

A unique structure for epidermal growth factor receptor bound to GW572016 (Lapatinib): relationships among protein conformation, inhibitor off-rate, and receptor activity in tumor cells

1 reference

12 December 2020

Biological effects in vitro of monoclonal antibodies to human epidermal growth factor receptors

1 reference

12 December 2020

Caveolin-1 phosphorylation in human squamous and epidermoid carcinoma cells: dependence on ErbB1 expression and Src activation

1 reference

12 December 2020

The type III epidermal growth factor receptor mutation. Biological significance and potential target for anti-cancer therapy

1 reference

12 December 2020

EGFRvIII-mediated radioresistance through a strong cytoprotective response

1 reference

12 December 2020

Vascular endothelial growth factor expression in head and neck squamous cell carcinoma

1 reference

12 December 2020

Combined epidermal growth factor receptor targeting with the tyrosine kinase inhibitor gefitinib (ZD1839) and the monoclonal antibody cetuximab (IMC-C225): superiority over single-agent receptor targeting.

1 reference

12 December 2020

Tumor cell and endothelial cell therapy of oral cancer by dual tyrosine kinase receptor blockade

1 reference

12 December 2020

In vivo enhancement of tumor radioresponse by C225 antiepidermal growth factor receptor antibody

1 reference

12 December 2020

Hyperfractionated or accelerated radiotherapy in head and neck cancer: a meta-analysis

1 reference

12 December 2020

ERBB receptors and cancer: the complexity of targeted inhibitors

1 reference

12 December 2020

Selecting lung cancer patients for treatment with epidermal growth factor receptor tyrosine kinase inhibitors by immunohistochemistry and fluorescence in situ hybridization--why, when, and how?

1 reference

12 December 2020

Randomized phase III trial results of panitumumab, a fully human anti-epidermal growth factor receptor monoclonal antibody, in metastatic colorectal cancer

1 reference

12 December 2020

AEE788: a dual family epidermal growth factor receptor/ErbB2 and vascular endothelial growth factor receptor tyrosine kinase inhibitor with antitumor and antiangiogenic activity

1 reference

12 December 2020

STAT3 activation abrogates growth factor dependence and contributes to head and neck squamous cell carcinoma tumor growth in vivo

1 reference

12 December 2020

Epidermal growth factor receptor-negative colorectal cancer: is there truly such an entity?

1 reference

12 December 2020

Synergistic antitumor effects of combined epidermal growth factor receptor and vascular endothelial growth factor receptor-2 targeted therapy

1 reference

12 December 2020

Signaling through ERBB receptors: multiple layers of diversity and control

1 reference

12 December 2020

Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib

1 reference

12 December 2020

A phase I clinical and pharmacokinetic study of oral CI-1033 in combination with docetaxel in patients with advanced solid tumors

1 reference

12 December 2020

GPCR-induced migration of breast carcinoma cells depends on both EGFR signal transactivation and EGFR-independent pathways.

1 reference

12 December 2020

Dual-agent molecular targeting of the epidermal growth factor receptor (EGFR): combining anti-EGFR antibody with tyrosine kinase inhibitor.

1 reference

12 December 2020

Increased HER2 gene copy number is associated with response to gefitinib therapy in epidermal growth factor receptor-positive non-small-cell lung cancer patients

1 reference

12 December 2020

Concurrent cetuximab, cisplatin, and concomitant boost radiotherapy for locoregionally advanced, squamous cell head and neck cancer: a pilot phase II study of a new combined-modality paradigm

1 reference

12 December 2020

Elevated levels of transforming growth factor alpha and epidermal growth factor receptor messenger RNA are early markers of carcinogenesis in head and neck cancer.

1 reference

12 December 2020

Phase 1 clinical and pharmacokinetics evaluation of oral CI-1033 in patients with refractory cancer

1 reference

12 December 2020

Epidermal Growth Factor Receptor Expression in Pretreatment Biopsies From Head and Neck Squamous Cell Carcinoma As a Predictive Factor for a Benefit From Accelerated Radiation Therapy in a Randomized Controlled Trial

1 reference

12 December 2020

Expression of oestrogen receptor and transforming growth factor-alpha in MCF-7 cells after exposure to fractionated irradiation

1 reference

12 December 2020

Targeting the epidermal growth factor receptor in radiotherapy: radiobiological mechanisms, preclinical and clinical results

1 reference

12 December 2020

Design and structure-activity relationship of a new class of potent VEGF receptor tyrosine kinase inhibitors

1 reference

12 December 2020

Nuclear interaction of EGFR and STAT3 in the activation of the iNOS/NO pathway

1 reference

12 December 2020

Phosphotyrosine interactome of the ErbB-receptor kinase family

1 reference

12 December 2020

Phase I study of anti--epidermal growth factor receptor antibody cetuximab in combination with radiation therapy in patients with advanced head and neck cancer

1 reference

12 December 2020

Radiosensitization by pan ErbB inhibitor CI-1033 in vitro and in vivo

1 reference

12 December 2020

Modulation of radiation response after epidermal growth factor receptor blockade in squamous cell carcinomas: inhibition of damage repair, cell cycle kinetics, and tumor angiogenesis

1 reference

12 December 2020

The epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 selectively potentiates radiation response of human tumors in nude mice, with a marked improvement in therapeutic index.

1 reference

12 December 2020

Sublethal irradiation promotes migration and invasiveness of glioma cells: implications for radiotherapy of human glioblastoma

1 reference

12 December 2020

Enhancement of antitumor activity of ionizing radiation by combined treatment with the selective epidermal growth factor receptor-tyrosine kinase inhibitor ZD1839 (Iressa).

1 reference

12 December 2020

Insulin-like growth factor-I receptor signaling and resistance to trastuzumab (Herceptin).

1 reference

12 December 2020

Structural basis for inhibition of the epidermal growth factor receptor by cetuximab

1 reference

12 December 2020

Insulin-like growth factor receptor I mediates resistance to anti-epidermal growth factor receptor therapy in primary human glioblastoma cells through continued activation of phosphoinositide 3-kinase signaling

1 reference

12 December 2020

Analysis of the dinucleotide repeat polymorphism in the epidermal growth factor receptor (EGFR) gene in head and neck cancer patients

1 reference

12 December 2020

Role of epidermal growth factor receptor pathway-targeted therapy in patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck

1 reference

12 December 2020

Co-regulation of B-Myb expression by E2F1 and EGF receptor

1 reference

12 December 2020

DNA double-strand breaks: signaling, repair and the cancer connection

1 reference

12 December 2020

Prostaglandin E2 activates mitogen-activated protein kinase/Erk pathway signaling and cell proliferation in non-small cell lung cancer cells in an epidermal growth factor receptor-independent manner.

1 reference

12 December 2020

Impact of epidermal growth factor receptor expression on survival and pattern of relapse in patients with advanced head and neck carcinoma.

1 reference

12 December 2020

The relative role of ErbB1-4 receptor tyrosine kinases in radiation signal transduction responses of human carcinoma cells

1 reference

12 December 2020

Trafficking of the ErbB receptors and its influence on signaling

1 reference

12 December 2020

Retinoic acid normalizes the increased gene transcription rate of TGF-alpha and EGFR in head and neck cancer cell lines

1 reference

12 December 2020

Phase III randomized trial of cisplatin plus placebo compared with cisplatin plus cetuximab in metastatic/recurrent head and neck cancer: an Eastern Cooperative Oncology Group study

1 reference

12 December 2020

Irreversible inhibitors of the EGF receptor may circumvent acquired resistance to gefitinib

1 reference

12 December 2020

Inverse relationship between epidermal growth factor receptor expression and radiocurability of murine carcinomas

1 reference

12 December 2020

The prognostic value of epidermal growth factor receptor is related to tumor differentiation and the overall treatment time of radiotherapy in squamous cell carcinomas of the head and neck.

1 reference

12 December 2020

ZD6474 inhibits vascular endothelial growth factor signaling, angiogenesis, and tumor growth following oral administration.

1 reference

12 December 2020

The EGFR family and its ligands in human cancer. signalling mechanisms and therapeutic opportunities

1 reference

12 December 2020

Ubiquitin ligase activity and tyrosine phosphorylation underlie suppression of growth factor signaling by c-Cbl/Sli-1

1 reference

12 December 2020

Human epidermal growth factor: isolation and chemical and biological properties

1 reference

12 December 2020

Activation of BAD by therapeutic inhibition of epidermal growth factor receptor and transactivation by insulin-like growth factor receptor

1 reference

12 December 2020

Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck

1 reference

12 December 2020

ERBB receptor tyrosine kinases and cellular radiation responses

1 reference

12 December 2020

Cell surface localization and density of the tumor-associated variant of the epidermal growth factor receptor, EGFRvIII.

1 reference

12 December 2020

Radiation-induced enhanced proliferation of human squamous cancer cells in vitro: a release from inhibition by epidermal growth factor

1 reference

12 December 2020

Diversification of Neu differentiation factor and epidermal growth factor signaling by combinatorial receptor interactions

1 reference

12 December 2020

Anti-tumor activity of the combination of cetuximab, an anti-EGFR blocking monoclonal antibody and ZD6474, an inhibitor of VEGFR and EGFR tyrosine kinases

1 reference

12 December 2020

Chemo-radiotherapy in patients with locally advanced nasopharyngeal carcinoma: a radiation therapy oncology group study

1 reference

12 December 2020

ZD6474--clinical experience to date

1 reference

12 December 2020

Acquired resistance to the antitumor effect of epidermal growth factor receptor-blocking antibodies in vivo: a role for altered tumor angiogenesis

1 reference

12 December 2020

Enhanced apoptosis with combination C225/radiation treatment serves as the impetus for clinical investigation in head and neck cancers

1 reference

12 December 2020

Advances in the treatment of locally advanced non-nasopharyngeal squamous cell carcinoma of the head and neck region

1 reference

12 December 2020

10.1007/S10147-006-0663-5

Identifiers

DOI

1 reference

release_akguotbmmzb6rf544vb2j3nvaq

16 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/akguotbmmzb6rf544vb2j3nvaq

24 November 2022

mapped directly with Wikidata item

1 reference