Inactivating Icmt ameliorates K-RAS-induced myeloproliferative disease. (Q36835230)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18502828%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

title

Inactivating Icmt ameliorates K-RAS-induced myeloproliferative disease (English)

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7 January 2020

3

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7 January 2020

Karin M Andersson

7

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7 January 2020

Stephen G. Young

8

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6

Anna-Karin M Sjogren

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7 January 2020

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2

Briony A Cutts

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7 January 2020

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Annika M Wahlstrom

1

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7 January 2020

Annika Lindskog

4

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7 January 2020

Christin Karlsson

5

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7 January 2020

Martin O Bergo

9

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7 January 2020

language of work or name

English

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publication date

23 May 2008

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7 January 2020

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7 January 2020

volume

112

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7 January 2020

issue

4

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7 January 2020

page(s)

1357-1365

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GGTase-I deficiency reduces tumor formation and improves survival in mice with K-RAS-induced lung cancer

7 January 2020

cites work

1 reference

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K-RasG12D expression induces hyperproliferation and aberrant signaling in primary hematopoietic stem/progenitor cells

29 September 2017

1 reference

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Rce1 deficiency accelerates the development of K-RAS-induced myeloproliferative disease

29 September 2017

1 reference

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Amide-substituted farnesylcysteine analogs as inhibitors of human isoprenylcysteine carboxyl methyltransferase

29 September 2017

1 reference

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The isoprenoid substrate specificity of isoprenylcysteine carboxylmethyltransferase: development of novel inhibitors

29 September 2017

1 reference

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A small-molecule inhibitor of isoprenylcysteine carboxyl methyltransferase with antitumor activity in cancer cells.

29 September 2017

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Postprenylation CAAX processing is required for proper localization of Ras but not Rho GTPases

29 September 2017

1 reference

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Controlling the location and activation of Rab GTPases

29 September 2017

1 reference

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Inactivation of Icmt inhibits transformation by oncogenic K-Ras and B-Raf

29 September 2017

1 reference

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Conditional expression of oncogenic K-ras from its endogenous promoter induces a myeloproliferative disease

29 September 2017

1 reference

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Somatic activation of oncogenic Kras in hematopoietic cells initiates a rapidly fatal myeloproliferative disorder

29 September 2017

1 reference

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Tumor induction by an endogenous K-ras oncogene is highly dependent on cellular context

29 September 2017

1 reference

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The role of FLT3 in haematopoietic malignancies

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515151

Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras

29 September 2017

1 reference

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Isoprenylcysteine carboxyl methyltransferase deficiency in mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515151

In vitro and in vivo effects of a farnesyltransferase inhibitor on Nf1-deficient hematopoietic cells

29 September 2017

1 reference

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K- and N-Ras are geranylgeranylated in cells treated with farnesyl protein transferase inhibitors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515151

BCR-ABL-induced oncogenesis is mediated by direct interaction with the SH2 domain of the GRB-2 adaptor protein

29 September 2017

1 reference

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Inducible gene targeting in mice

29 September 2017

1 reference

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ras oncogenes in human cancer: a review

29 September 2017

1 reference

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29 September 2017

1 reference

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Rab GTPases containing a CAAX motif are processed post-geranylgeranylation by proteolysis and methylation.

29 September 2017

1 reference

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Somatic activation of a conditional KrasG12D allele causes ineffective erythropoiesis in vivo

5 September 2018

1 reference

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Endogenous oncogenic K-ras(G12D) stimulates proliferation and widespread neoplastic and developmental defects.

5 September 2018

1 reference

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Hematologic effects of inactivating the Ras processing enzyme Rce1.

5 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515151

Conditional gene targeting in macrophages and granulocytes using LysMcre mice.

5 September 2018

1 reference

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Loss of NF1 results in activation of the Ras signaling pathway and leads to aberrant growth in haematopoietic cells

5 September 2018

1 reference

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Inhibition of farnesyltransferase induces regression of mammary and salivary carcinomas in ras transgenic mice

5 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18502828

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1182/BLOOD-2007-06-094060

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18502828%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18502828%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

1 reference