STAT3 and suppressor of cytokine signaling 3: potential targets in lung inflammatory responses (Q36871967)

16 August 2017

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title

STAT3 and suppressor of cytokine signaling 3: potential targets in lung inflammatory responses (English)

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16 August 2017

2

Peter A Ward

1 reference

16 August 2017

Hongwei Gao

1

1 reference

PubMed ID

17614756

16 August 2017

language of work or name

English

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publication date

1 July 2007

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Expert Opinion on Therapeutic Targets

16 August 2017

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16 August 2017

11

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16 August 2017

7

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16 August 2017

869-880

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https://api.crossref.org/works/10.1517%2F14728222.11.7.869

16 August 2017

1 reference

Stat-3 is required for pulmonary homeostasis during hyperoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.869

Jaks and STATs: biological implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.869

Signal transducers and activators of transcription as regulators of growth, apoptosis and breast development

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.869

STAT proteins: signal tranducers and activators of transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.869

The role of STATs in transcriptional control and their impact on cellular function

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.869

A critical role for Stat3 signaling in immune tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.869

Essential role of STAT3 in the control of the acute-phase response as revealed by inducible gene inactivation [correction of activation] in the liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.869

A mutant form of JAB/SOCS1 augments the cytokine-induced JAK/STAT pathway by accelerating degradation of wild-type JAB/CIS family proteins through the SOCS-box.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.869

STAT3 in immune responses and inflammatory bowel diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.869

Cardiomyocyte-restricted knockout of STAT3 results in higher sensitivity to inflammation, cardiac fibrosis, and heart failure with advanced age

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.869

Endothelial cells require STAT3 for protection against endotoxin-induced inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.869

STAT3 is required for Flt3L-dependent dendritic cell differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.869

The STAT3 isoforms alpha and beta have unique and specific functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.869

STAT3 deletion during hematopoiesis causes Crohn's disease-like pathogenesis and lethality: a critical role of STAT3 in innate immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.869

STAT3 activation in response to growth factors or cytokines participates in retina precursor proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.869

STAT3-mediated signaling in the determination of rod photoreceptor cell fate in mouse retina.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.869

Carbon monoxide differentially modulates STAT1 and STAT3 and inhibits apoptosis via a phosphatidylinositol 3-kinase/Akt and p38 kinase-dependent STAT3 pathway during anoxia-reoxygenation injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.869

Pigment epithelium-derived factor (PEDF) is an endogenous antiinflammatory factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.869

Osteoporosis with increased osteoclastogenesis in hematopoietic cell-specific STAT3-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.869

The role of suppressors of cytokine signaling (SOCS) proteins in regulation of the immune response

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.869

Targeted Lung Expression of Interleukin-11 Enhances Murine Tolerance of 100% Oxygen and Diminishes Hyperoxia-Induced DNA Fragmentation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.869

Regulation of the immune system by SOCS family adaptor proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.869

IL-6 induces an anti-inflammatory response in the absence of SOCS3 in macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.869

Suppressors of cytokine signaling and immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.869

Loss of SOCS3 in T helper cells resulted in reduced immune responses and hyperproduction of interleukin 10 and transforming growth factor-beta 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.869

CIS3/SOCS3/SSI3 plays a negative regulatory role in STAT3 activation and intestinal inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.869

Induction of the cytokine signal regulator SOCS3/CIS3 as a therapeutic strategy for treating inflammatory arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.869

SOCS-3 negatively regulates innate and adaptive immune mechanisms in acute IL-1-dependent inflammatory arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.869

Sepsis-induced SOCS-3 expression is immunologically restricted to phagocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.869

Transcriptional stimulation of the surfactant protein B gene by STAT3 in respiratory epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.869

Hyperoxia in the intensive care unit: why more is not always better.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.869

Synergy between signal transducer and activator of transcription 3 and retinoic acid receptor-alpha in regulation of the surfactant protein B gene in the lung

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.869

Interleukin-11 and Interleukin-6 Protect Cultured Human Endothelial Cells from H2O2-Induced Cell Death

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.869

Oxidants and signaling by mitogen-activated protein kinases in lung epithelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.869

STAT3 activation inhibits human bronchial epithelial cell apoptosis in response to cigarette smoke exposure

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.869

In vivo suppression of NF-kappa B and preservation of I kappa B alpha by interleukin-10 and interleukin-13.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.869

Adult respiratory distress syndrome: a systemic overview of incidence and risk factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.869

Activation of the STAT pathway in acute lung injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.869

Inhibition of the Src and Jak kinases protects against lipopolysaccharide-induced acute lung injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.869

Blockade of interleukin 6 trans signaling suppresses T-cell resistanceagainst apoptosis in chronic intestinal inflammation: Evidence in Crohn diseaseand experimental colitis in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.869

Roles of interleukin-6 in activation of STAT proteins and recruitment of neutrophils during Escherichia coli pneumonia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.869

Essential role of induced nitric oxide in the initiation of the inflammatory response after hemorrhagic shock

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.869

Inflammatory response to pulmonary ischemia-reperfusion injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.869

Carbon monoxide inhibition of apoptosis during ischemia-reperfusion lung injury is dependent on the p38 mitogen-activated protein kinase pathway and involves caspase 3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.869

Interleukin-6 regulation of direct lung ischemia reperfusion injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.869

Respiratory viral infections drive chemokine expression and exacerbate the asthmatic response

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.869

Surfactant protein B inhibits endotoxin-induced lung inflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.869

Reactive oxygen species mediate virus-induced STAT activation: role of tyrosine phosphatases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.869

Measles virus activates NF-kappa B and STAT transcription factors and production of IFN-alpha/beta and IL-6 in the human lung epithelial cell line A549.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.869

Influenza virus infection induces metallothionein gene expression in the mouse liver and lung by overlapping but distinct molecular mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.869

The role of CXC chemokines in pulmonary fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.869

Prognostic significance of histopathologic subsets in idiopathic pulmonary fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.869

Idiopathic pulmonary fibrosis challenges for the future.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.869

Inverse effects of interleukin-6 on apoptosis of fibroblasts from pulmonary fibrosis and normal lungs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.869

Lipoxin A4 inhibits proliferation of human lung fibroblasts induced by connective tissue growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.869

Adenoviral gene transfer of connective tissue growth factor in the lung induces transient fibrosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.869

Connective tissue growth factor is crucial to inducing a profibrotic environment in "fibrosis-resistant" BALB/c mouse lungs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.869

Asthma: mechanisms of disease persistence and progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.869

JAK-STAT signaling in asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.869

Polymorphisms in signal transducer and activator of transcription 3 and lung function in asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.869

SOCS-3 regulates onset and maintenance of T(H)2-mediated allergic responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.869

Targeting signal transducer and activator of transcription 3 with G-quartet oligonucleotides: a potential novel therapy for head and neck cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.869

Hypericum perforatum attenuates the development of carrageenan-induced lung injury in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.869

St John's wort (Hypericum perforatum L.): a review of its chemistry, pharmacology and clinical properties.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.869

Flavonoids as antioxidant agents: importance of their interaction with biomembranes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.869

Quercetin, coenzyme Q10, and L-canavanine as protective agents against lipid peroxidation and nitric oxide generation in endotoxin-induced shock in rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.11.7.869

10.1517/14728222.11.7.869

21 January 2018

Identifiers

DOI

1 reference

16 August 2017

1 reference

PubMed ID

17614756