HIV-1 Vpr protein inhibits telomerase activity via the EDD-DDB1-VPRBP E3 ligase complex (Q36890536)

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29 February 2020

title

HIV-1 Vpr protein inhibits telomerase activity via the EDD-DDB1-VPRBP E3 ligase complex (English)

1 reference

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29 February 2020

6

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29 February 2020

Jae-il Park

7

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29 February 2020

author name string

Xin Wang

1

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29 February 2020

Shailbala Singh

2

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29 February 2020

Hae-Yun Jung

3

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29 February 2020

Guojun Yang

4

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29 February 2020

Sohee Jun

5

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29 February 2020

language of work or name

English

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publication date

23 April 2013

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Journal of Biological Chemistry

29 February 2020

published in

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volume

288

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issue

22

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29 February 2020

page(s)

15474-15480

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describes a project that uses

29 February 2020

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3668709/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Dyrk2-associated EDD-DDB1-VprBP E3 ligase inhibits telomerase by TERT degradation

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Vif hijacks CBF-β to degrade APOBEC3G and promote HIV-1 infection

29 September 2017

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Vpx relieves inhibition of HIV-1 infection of macrophages mediated by the SAMHD1 protein

29 September 2017

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29 September 2017

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HIV-1 accessory protein Vpr: relevance in the pathogenesis of HIV and potential for therapeutic intervention

29 September 2017

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Telomerase modulates Wnt signalling by association with target gene chromatin

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29 September 2017

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A non-canonical function of zebrafish telomerase reverse transcriptase is required for developmental hematopoiesis

29 September 2017

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Assembly with the Cul4A-DDB1DCAF1 ubiquitin ligase protects HIV-1 Vpr from proteasomal degradation.

29 September 2017

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VprBP targets Merlin to the Roc1-Cul4A-DDB1 E3 ligase complex for degradation

29 September 2017

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A key role for telomerase reverse transcriptase unit in modulating human embryonic stem cell proliferation, cell cycle dynamics, and in vitro differentiation

29 September 2017

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HIV-1 Vpr-mediated G2 arrest involves the DDB1-CUL4AVPRBP E3 ubiquitin ligase

29 September 2017

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DDB1 and Cul4A are required for human immunodeficiency virus type 1 Vpr-induced G2 arrest

29 September 2017

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HIV1 Vpr arrests the cell cycle by recruiting DCAF1/VprBP, a receptor of the Cul4-DDB1 ubiquitin ligase

29 September 2017

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The structure and function of telomerase reverse transcriptase

29 September 2017

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Beginning to understand the end of the chromosome

29 September 2017

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Induction of APOBEC3G Ubiquitination and Degradation by an HIV-1 Vif-Cul5-SCF Complex

29 September 2017

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HIV-1 Vif protein binds the editing enzyme APOBEC3G and induces its degradation

29 September 2017

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The antiretroviral enzyme APOBEC3G is degraded by the proteasome in response to HIV-1 Vif

29 September 2017

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29 September 2017

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Vpr R77Q is associated with long-term nonprogressive HIV infection and impaired induction of apoptosis

29 September 2017

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Activation of the ATR-mediated DNA damage response by the HIV-1 viral protein R.

29 September 2017

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NMR structure of the HIV-1 regulatory protein VPR

29 September 2017

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Cooperation between p53 mutation and high telomerase transgenic expression in spontaneous cancer development

29 September 2017

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29 September 2017

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Constitutive telomerase expression promotes mammary carcinomas in aging mice

29 September 2017

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A novel human WD protein, h-beta TrCp, that interacts with HIV-1 Vpu connects CD4 to the ER degradation pathway through an F-box motif

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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27 June 2018

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Overexpression of telomerase confers growth advantage, stress resistance, and enhanced differentiation of ESCs toward the hematopoietic lineage.

4 September 2018

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Effect of productive in vitro human immunodeficiency virus or simian immunodeficiency virus infection on telomerase activity in lymphoid and nonlymphoid cells

4 September 2018

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Human immunodeficiency virus type 1 modulates telomerase activity in peripheral blood lymphocytes

4 September 2018

1 reference

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Gene Defects Clustered at the C-Terminus of the vpr Gene of HIV-1 in Long-Term Nonprogressing Mother and Child Pair:In VivoEvolution of vpr Quasispecies in Blood and Plasma

4 September 2018

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Crossref

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HIV-1 infection downregulates nuclear telomerase activity on lymphoblastoic cells without affecting the enzymatic components at the transcriptional level

21 January 2018

1 reference

PubMed

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inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M112.416735

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23612978%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23612978%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

1 reference