Telomerase modulates Wnt signalling by association with target gene chromatin (Q24310084)

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DNA polymerase binding

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Telomerase reverse transcriptase

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1 reference

15

Steven E Artandi

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author name string

Jae-Il Park

1

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Andrew S Venteicher

2

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Ji Yeon Hong

3

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Jinkuk Choi

4

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Sohee Jun

5

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Marina Shkreli

6

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Woody Chang

7

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Zhaojing Meng

8

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Peggie Cheung

9

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Hong Ji

10

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Margaret McLaughlin

11

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Timothy D Veenstra

12

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Roel Nusse

13

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Pierre D McCrea

describes a project that uses

14

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language of work or name

English

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publication date

2 July 2009

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published in

Nature

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volume

460

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issue

7251

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page(s)

66-72

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ImageJ

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4349391/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Identification of ATPases pontin and reptin as telomerase components essential for holoenzyme assembly

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The chromatin remodelling factor Brg-1 interacts with beta-catenin to promote target gene activation

19 March 2017

1 reference

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CDK8 is a colorectal cancer oncogene that regulates beta-catenin activity

19 March 2017

1 reference

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Increased epidermal tumors and increased skin wound healing in transgenic mice overexpressing the catalytic subunit of telomerase, mTERT, in basal keratinocytes.

19 March 2017

1 reference

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Telomere dysfunction impairs DNA repair and enhances sensitivity to ionizing radiation

19 March 2017

1 reference

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Requirement for beta-catenin in anterior-posterior axis formation in mice

19 March 2017

1 reference

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Evidence that absence of Wnt-3a signaling promotes neuralization instead of paraxial mesoderm development in the mouse

19 March 2017

1 reference

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Conditional telomerase induction causes proliferation of hair follicle stem cells

19 March 2017

1 reference

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Effects of telomerase and telomere length on epidermal stem cell behavior

19 March 2017

1 reference

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Negative feedback loop of Wnt signaling through upregulation of conductin/axin2 in colorectal and liver tumors

19 March 2017

1 reference

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Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4

19 March 2017

1 reference

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Wnt signalling in stem cells and cancer

19 March 2017

1 reference

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Restoration of p53 function leads to tumour regression in vivo

7 April 2017

1 reference

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Regulation of telomerase by telomeric proteins

7 April 2017

1 reference

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De Novo hair follicle morphogenesis and hair tumors in mice expressing a truncated beta-catenin in skin

7 April 2017

1 reference

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Essential role of mouse telomerase in highly proliferative organs

7 April 2017

1 reference

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Syndromes of telomere shortening

7 April 2017

1 reference

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New regulators of Wnt/beta-catenin signaling revealed by integrative molecular screening

27 September 2017

1 reference

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A non-canonical function of zebrafish telomerase reverse transcriptase is required for developmental hematopoiesis

27 September 2017

1 reference

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Pygopus activates Wingless target gene transcription through the mediator complex subunits Med12 and Med13.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4349391

TERT promotes epithelial proliferation through transcriptional control of a Myc- and Wnt-related developmental program

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4349391

A key role for telomerase reverse transcriptase unit in modulating human embryonic stem cell proliferation, cell cycle dynamics, and in vitro differentiation

27 September 2017

1 reference

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Telomere uncapping in progenitor cells with critical telomere shortening is coupled to S-phase progression in vivo

27 September 2017

1 reference

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The many ways of Wnt in cancer

27 September 2017

1 reference

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Wnt signaling: is the party in the nucleus?

27 September 2017

1 reference

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The telomerase reverse transcriptase regulates chromatin state and DNA damage responses.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4349391

Coupling segmentation to axis formation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4349391

Distinct dosage requirements for the maintenance of long and short telomeres in mTert heterozygous mice

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4349391

The Cdx1 homeodomain protein: an integrator of posterior signaling in the mouse

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4349391

Transient activation of beta -catenin signaling in cutaneous keratinocytes is sufficient to trigger the active growth phase of the hair cycle in mice.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4349391

Telomerase contributes to tumorigenesis by a telomere length-independent mechanism

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4349391

Connecting chromosomes, crisis, and cancer

27 September 2017

1 reference

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Constitutive telomerase expression promotes mammary carcinomas in aging mice

27 September 2017

1 reference

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Retinoic acid regulation of Cdx1: an indirect mechanism for retinoids and vertebral specification

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4349391

Proteins of the Myc network: essential regulators of cell growth and differentiation.

27 September 2017

1 reference

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Overexpression of cadherins and underexpression of beta-catenin inhibit dorsal mesoderm induction in early Xenopus embryos

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4349391

Ectopic expression of the proto-oncogene int-1 in Xenopus embryos leads to duplication of the embryonic axis.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4349391

Understanding the words of chromatin regulation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4349391

eFGF, Xcad3 and Hox genes form a molecular pathway that establishes the anteroposterior axis in Xenopus.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4349391

Analysis of the vestigial tail mutation demonstrates that Wnt-3a gene dosage regulates mouse axial development.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4349391

TERT promotes cellular and organismal survival independently of telomerase activity

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4349391

Mediator is a transducer of Wnt/beta-catenin signaling.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4349391

Overexpression of telomerase confers growth advantage, stress resistance, and enhanced differentiation of ESCs toward the hematopoietic lineage.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4349391

Beta-catenin directly displaces Groucho/TLE repressors from Tcf/Lef in Wnt-mediated transcription activation

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4349391

Transient activation of beta-catenin signalling in adult mouse epidermis is sufficient to induce new hair follicles but continuous activation is required to maintain hair follicle tumours

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4349391

Telomerase modulates expression of growth-controlling genes and enhances cell proliferation

29 November 2018

1 reference

12 December 2020

The entire mesodermal mantle behaves as Spemann's organizer in dorsoanterior enhanced Xenopus laevis embryos

1 reference

12 December 2020

Immunodetection of human telomerase reverse-transcriptase (hTERT) re-appraised: nucleolin and telomerase cross paths

1 reference

12 December 2020

Wnt-3a is required for somite specification along the anteroposterior axis of the mouse embryo and for regulation of cdx-1 expression

1 reference

12 December 2020

Cooperative interactions of p53 mutation, telomere dysfunction, and chronic liver damage in hepatocellular carcinoma progression

1 reference

12 December 2020

Identifiers

DOI

10.1038/NATURE08137

1 reference

Dimensions Publication ID

815668

1049743007

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815668

1 reference

1 reference

1 reference