Multidrug resistance in epilepsy: a pharmacogenomic update (Q36895830)

16 August 2017

1 reference

title

Multidrug resistance in epilepsy: a pharmacogenomic update (English)

1 reference

16 August 2017

multiple drug resistance

1 reference

1 reference

Sarah K Tate

1

1 reference

PubMed ID

17661727

16 August 2017

Sanjay M Sisodiya

series ordinal

2

1 reference

PubMed ID

17661727

16 August 2017

language of work or name

English

0 references

publication date

1 July 2007

1 reference

Expert Opinion on Pharmacotherapy

16 August 2017

1 reference

16 August 2017

8

1 reference

16 August 2017

10

1 reference

16 August 2017

1441-1449

1 reference

Drug resistance in epilepsy: putative neurobiologic and clinical mechanisms

16 August 2017

1 reference

https://api.crossref.org/works/10.1517%2F14656566.8.10.1441

Potential role of drug transporters in the pathogenesis of medically intractable epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.8.10.1441

Molecular and cellular mechanisms of pharmacoresistance in epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.8.10.1441

Defining intractability: comparisons among published definitions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.8.10.1441

A novel mechanism underlying drug resistance in chronic epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.8.10.1441

Effect of valproic acid on sodium currents in cortical neurons from patients with pharmaco-resistant temporal lobe epilepsy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.8.10.1441

Multidrug resistance protein MRP2 contributes to blood-brain barrier function and restricts antiepileptic drug activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.8.10.1441

Transport of amino acid-related compounds mediated by L-type amino acid transporter 1 (LAT1): insights into the mechanisms of substrate recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.8.10.1441

RLIP76, a non-ABC transporter, and drug resistance in epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.8.10.1441

Expression of the multidrug transporter MRP2 in the blood-brain barrier after pilocarpine-induced seizures in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.8.10.1441

Induction of P-glycoprotein in lymphocytes by carbamazepine and rifampicin: the role of nuclear hormone response elements

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.8.10.1441

Expression of multidrug transporters MRP1, MRP2, and BCRP shortly after status epilepticus, during the latent period, and in chronic epileptic rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.8.10.1441

Vascular colocalization of P-glycoprotein, multidrug-resistance associated protein 1, breast cancer resistance protein and major vault protein in human epileptogenic pathologies

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.8.10.1441

A pilot study on brain-to-plasma partition of 10,11-dyhydro-10-hydroxy-5H-dibenzo(b,f)azepine-5-carboxamide and MDR1 brain expression in epilepsy patients not responding to oxcarbazepine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.8.10.1441

Comparison of brain extracellular fluid, brain tissue, cerebrospinal fluid, and serum concentrations of antiepileptic drugs measured intraoperatively in patients with intractable epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.8.10.1441

Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.8.10.1441

P-glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.8.10.1441

In vivo evidence for P-glycoprotein-mediated transport of phenytoin at the blood-brain barrier of rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.8.10.1441

P-glycoprotein and multidrug resistance-associated protein are involved in the regulation of extracellular levels of the major antiepileptic drug carbamazepine in the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.8.10.1441

P-glycoprotein-mediated efflux of antiepileptic drugs: preliminary studies in mdr1a knockout mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.8.10.1441

The multidrug transporter hypothesis of drug resistance in epilepsy: Proof-of-principle in a rat model of temporal lobe epilepsy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.8.10.1441

Carbamazepine is not a substrate for P-glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.8.10.1441

Mechanisms of antiepileptic drug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.8.10.1441

Functional polymorphisms of the human multidrug-resistance gene: multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.8.10.1441

Response to antiretroviral treatment in HIV-1-infected individuals with allelic variants of the multidrug resistance transporter 1: a pharmacogenetics study

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.8.10.1441

MDR1 gene polymorphisms and disposition of the P-glycoprotein substrate fexofenadine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.8.10.1441

Identification of functionally variant MDR1 alleles among European Americans and African Americans

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.8.10.1441

A "silent" polymorphism in the MDR1 gene changes substrate specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.8.10.1441

Pharmacogenetics goes genomic

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.8.10.1441

Complex haplotypic effects of the ABCB1 gene on epilepsy treatment response.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.8.10.1441

Lack of association between the C3435T polymorphism in the human multidrug resistance (MDR1) gene and response to antiepileptic drug treatment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.8.10.1441

Clinical factors and ABCB1 polymorphisms in prediction of antiepileptic drug response: a prospective cohort study

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.8.10.1441

ABCB1 polymorphisms influence the response to antiepileptic drugs in Japanese epilepsy patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.8.10.1441

A polymorphism in the VKORC1 gene is associated with an interindividual variability in the dose-anticoagulant effect of warfarin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.8.10.1441

Genetic predictors of the maximum doses patients receive during clinical use of the anti-epileptic drugs carbamazepine and phenytoin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.8.10.1441

Alternative ion channel splicing in mesial temporal lobe epilepsy and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.8.10.1441

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.8.10.1441

Analysis of genetically complex epilepsies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.8.10.1441

Complement factor H polymorphism in age-related macular degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.8.10.1441

Functional SNPs in the lymphotoxin-alpha gene that are associated with susceptibility to myocardial infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.8.10.1441

High-resolution whole-genome association study of Parkinson disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.8.10.1441

Genome-wide association study identifies a second prostate cancer susceptibility variant at 8q24.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.8.10.1441

Genome-wide association study of prostate cancer identifies a second risk locus at 8q24

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.8.10.1441

A genome-wide association study identifies novel risk loci for type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.8.10.1441

A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.8.10.1441

Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.8.10.1441

A variant in CDKAL1 influences insulin response and risk of type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.8.10.1441

A genome-wide association study identifies IL23R as an inflammatory bowel disease gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.8.10.1441

Novel Crohn disease locus identified by genome-wide association maps to a gene desert on 5p13.1 and modulates expression of PTGER4

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.8.10.1441

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.8.10.1441

Global variation in copy number in the human genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.8.10.1441

Relative impact of nucleotide and copy number variation on gene expression phenotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.8.10.1441

Copy number polymorphism in Fcgr3 predisposes to glomerulonephritis in rats and humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.8.10.1441

Interaction of antiepileptic drugs with human P-glycoprotein in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.8.10.1441

Association of Multidrug Resistance in Epilepsy with a Polymorphism in the Drug-Transporter GeneABCB1

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.8.10.1441

A common polymorphism in the SCN1A gene associates with phenytoin serum levels at maintenance dose

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.8.10.1441

10.1517/14656566.8.10.1441

21 January 2018

Identifiers

DOI

1 reference

16 August 2017

1 reference

PubMed ID

17661727