Androgens promote prostate cancer cell growth through induction of autophagy. (Q36932530)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23250485%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

title

Androgens promote prostate cancer cell growth through induction of autophagy (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23250485%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

0 references

1 reference

1 reference

5

1 reference

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20 February 2020

Daniel E Frigo

9

1 reference

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20 February 2020

author name string

Yan Shi

1

1 reference

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20 February 2020

Jenny J Han

2

1 reference

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20 February 2020

Jayantha B Tennakoon

3

1 reference

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20 February 2020

Fabiola F Mehta

4

1 reference

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20 February 2020

Alan R Burns

6

1 reference

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20 February 2020

Matthew K Howe

7

1 reference

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20 February 2020

Donald P McDonnell

8

1 reference

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20 February 2020

publication date

18 December 2012

1 reference

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20 February 2020

published in

Molecular Endocrinology

1 reference

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20 February 2020

volume

27

1 reference

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20 February 2020

issue

2

1 reference

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20 February 2020

page(s)

280-295

1 reference

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describes a project that uses

20 February 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3683804/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Guidelines for the use and interpretation of assays for monitoring autophagy

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Thyroid hormone stimulates hepatic lipid catabolism via activation of autophagy

29 September 2017

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Reactive oxygen species induced by p66Shc longevity protein mediate nongenomic androgen action via tyrosine phosphorylation signaling to enhance tumorigenicity of prostate cancer cells

29 September 2017

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29 September 2017

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Punctate LC3B expression is a common feature of solid tumors and associated with proliferation, metastasis, and poor outcome

29 September 2017

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Activation of androgen receptor, lipogenesis, and oxidative stress converged by SREBP-1 is responsible for regulating growth and progression of prostate cancer cells.

29 September 2017

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29 September 2017

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Suppression of autophagy by FIP200 deletion inhibits mammary tumorigenesis

29 September 2017

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Acetylation targets the M2 isoform of pyruvate kinase for degradation through chaperone-mediated autophagy and promotes tumor growth.

29 September 2017

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AMPK-mediated autophagy is a survival mechanism in androgen-dependent prostate cancer cells subjected to androgen deprivation and hypoxia

29 September 2017

1 reference

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Pancreatic cancers require autophagy for tumor growth

29 September 2017

1 reference

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Androgens modulate autophagy and cell death via regulation of the endoplasmic reticulum chaperone glucose-regulated protein 78/BiP in prostate cancer cells

29 September 2017

1 reference

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Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis.

29 September 2017

1 reference

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The pINDUCER lentiviral toolkit for inducible RNA interference in vitro and in vivo

29 September 2017

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Involvement of autophagy in oncogenic K-Ras-induced malignant cell transformation

29 September 2017

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29 September 2017

Autophagy and metabolism

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Metabolic alterations and targeted therapies in prostate cancer

29 September 2017

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CaM kinase kinase beta-mediated activation of the growth regulatory kinase AMPK is required for androgen-dependent migration of prostate cancer cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683804

Dengue virus-induced autophagy regulates lipid metabolism

29 September 2017

1 reference

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WNT11 expression is induced by estrogen-related receptor alpha and beta-catenin and acts in an autocrine manner to increase cancer cell migration

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683804

The autophagic tumor stroma model of cancer: Role of oxidative stress and ketone production in fueling tumor cell metabolism

29 September 2017

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29 September 2017

1 reference

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Autophagy in mammalian development and differentiation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683804

Abrogation of de novo lipogenesis by stearoyl-CoA desaturase 1 inhibition interferes with oncogenic signaling and blocks prostate cancer progression in mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683804

Dominant uptake of fatty acid over glucose by prostate cells: a potential new diagnostic and therapeutic approach

29 September 2017

1 reference

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Methods in mammalian autophagy research

29 September 2017

1 reference

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Autophagy and adipogenesis: implications in obesity and type II diabetes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683804

Adipose-specific deletion of autophagy-related gene 7 (atg7) in mice reveals a role in adipogenesis

29 September 2017

1 reference

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Autophagy regulates adipose mass and differentiation in mice

29 September 2017

1 reference

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Targeted deletion of autophagy-related 5 (atg5) impairs adipogenesis in a cellular model and in mice

29 September 2017

1 reference

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Disruption of PPARgamma signaling results in mouse prostatic intraepithelial neoplasia involving active autophagy.

29 September 2017

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The double-edged sword of autophagy modulation in cancer

29 September 2017

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Starving the addiction: new opportunities for durable suppression of AR signaling in prostate cancer

29 September 2017

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Targeting the PI3K/AKT pathway for the treatment of prostate cancer

29 September 2017

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Autophagy regulates lipid metabolism

29 September 2017

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Fatty acid synthase: a metabolic enzyme and candidate oncogene in prostate cancer

29 September 2017

1 reference

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Inhibition of autophagy by 3-MA enhances the effect of 5-FU-induced apoptosis in colon cancer cells

29 September 2017

1 reference

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Autophagy provides nutrients but can lead to Chop-dependent induction of Bim to sensitize growth factor-deprived cells to apoptosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683804

The tumor suppressor gene ARHI regulates autophagy and tumor dormancy in human ovarian cancer cells

29 September 2017

1 reference

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Development of a small-molecule serum- and glucocorticoid-regulated kinase-1 antagonist and its evaluation as a prostate cancer therapeutic.

29 September 2017

1 reference

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Androgen levels increase by intratumoral de novo steroidogenesis during progression of castration-resistant prostate cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683804

Mitochondrial redox signaling by p66Shc is involved in regulating androgenic growth stimulation of human prostate cancer cells.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683804

Differential effects of prostate cancer therapeutics on neuroendocrine transdifferentiation

29 September 2017

1 reference

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Oxidative stress is inherent in prostate cancer cells and is required for aggressive phenotype

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683804

Autophagy fights disease through cellular self-digestion

29 September 2017

1 reference

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Autophagy in the Pathogenesis of Disease

29 September 2017

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Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683804

Role of autophagy in cancer

29 September 2017

1 reference

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Androgen-dependent regulation of medium and long chain fatty acids uptake in prostate cancer

29 September 2017

1 reference

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How to interpret LC3 immunoblotting

29 September 2017

1 reference

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p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy

29 September 2017

1 reference

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Dissection of the autophagosome maturation process by a novel reporter protein, tandem fluorescent-tagged LC3

29 September 2017

1 reference

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Squalene synthase, a determinant of Raft-associated cholesterol and modulator of cancer cell proliferation.

29 September 2017

1 reference

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Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4

29 September 2017

1 reference

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Expanding the therapeutic use of androgens via selective androgen receptor modulators (SARMs)

29 September 2017

1 reference

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The energy sensing LKB1-AMPK pathway regulates p27(kip1) phosphorylation mediating the decision to enter autophagy or apoptosis

29 September 2017

1 reference

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Autophagy inhibition enhances therapy-induced apoptosis in a Myc-induced model of lymphoma

29 September 2017

1 reference

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Autophagy in cancer: good, bad, or both?

29 September 2017

1 reference

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A single lentiviral vector platform for microRNA-based conditional RNA interference and coordinated transgene expression

29 September 2017

1 reference

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Lysosomal turnover, but not a cellular level, of endogenous LC3 is a marker for autophagy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683804

Increased lipogenesis in cancer cells: new players, novel targets.

29 September 2017

1 reference

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Fatty acid oxidation is a dominant bioenergetic pathway in prostate cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683804

Androgen axis in prostate cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683804

Adding chloroquine to conventional treatment for glioblastoma multiforme: a randomized, double-blind, placebo-controlled trial

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683804

Increased expression of genes converting adrenal androgens to testosterone in androgen-independent prostate cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683804

ATP citrate lyase inhibition can suppress tumor cell growth

29 September 2017

1 reference

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The role of autophagy in cancer development and response to therapy.

29 September 2017

1 reference

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The coordinate regulation of the p53 and mTOR pathways in cells

29 September 2017

1 reference

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Androgens, lipogenesis and prostate cancer.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683804

Inhibition of macroautophagy triggers apoptosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683804

Peroxisomal branched chain fatty acid beta-oxidation pathway is upregulated in prostate cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683804

Fatty acid synthase: a metabolic oncogene in prostate cancer?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683804

Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683804

Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683804

Androgens stimulate coordinated lipogenic gene expression in normal target tissues in vivo

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683804

Autophagy delays sulindac sulfide-induced apoptosis in the human intestinal colon cancer cell line HT-29.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683804

The tumor suppressor PTEN positively regulates macroautophagy by inhibiting the phosphatidylinositol 3-kinase/protein kinase B pathway

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683804

LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683804

De novo lipogenesis protects cancer cells from free radicals and chemotherapeutics by promoting membrane lipid saturation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683804

The lipoatrophic caveolin-1 deficient mouse model reveals autophagy in mature adipocytes.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683804

Autophagy inhibition induces atrophy and myopathy in adult skeletal muscles.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683804

Autophagy is required to maintain muscle mass.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683804

The MAP1-LC3 conjugation system is involved in lipid droplet formation

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683804

Autophagy protects LNCaP cells under androgen deprivation conditions

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683804

p38alpha MAP kinase as a sensor of reactive oxygen species in tumorigenesis.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683804

Increased fatty acid synthase expression and activity during progression of prostate cancer in the TRAMP model

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683804

11C-acetate PET imaging of prostate cancer: detection of recurrent disease at PSA relapse

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683804

Carbon-11 acetate positron emission tomography can detect local recurrence of prostate cancer

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683804

11C-acetate PET imaging of prostate cancer.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683804

Androgens stimulate lipogenic gene expression in prostate cancer cells by activation of the sterol regulatory element-binding protein cleavage activating protein/sterol regulatory element-binding protein pathway

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683804

Chemical inhibition of acetyl-CoA carboxylase induces growth arrest and cytotoxicity selectively in cancer cells

4 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23250485

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Intraprostatic androgens and androgen-regulated gene expression persist after testosterone suppression: therapeutic implications for castration-resistant prostate cancer

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23250485

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1210/ME.2012-1260

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23250485%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23250485%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

1 reference