Cytoplasmic RNA viruses as potential vehicles for the delivery of therapeutic small RNAs. (Q36937406)

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3 March 2020

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Cytoplasmic RNA viruses as potential vehicles for the delivery of therapeutic small RNAs (English)

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pharmaceutical preparation

3 March 2020

main subject

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PubMed

biomedical investigative technique

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Fernando Almazan

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3

1 reference

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3 March 2020

Juan C Gallego-Gomez

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4

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author name string

Natalia Campillo-Pedroza

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2

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publication date

7 June 2013

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6 August 2019

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3 November 2019

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3 March 2020

page(s)

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Creative Commons Attribution 2.0 Generic

3 March 2020

copyright license

8 references

25 June 2019

6 August 2019

19 September 2019

3 November 2019

1 June 2020

5 August 2020

29 October 2020

Attenuation of Semliki Forest virus neurovirulence by microRNA-mediated detargeting

23 November 2020

0 references

1 reference

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Evidence for a cytoplasmic microprocessor of pri-miRNAs

29 September 2017

1 reference

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RNA virus microRNA that mimics a B-cell oncomiR.

29 September 2017

1 reference

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Arbovirus-derived piRNAs exhibit a ping-pong signature in mosquito cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685532

Biogenesis of mammalian microRNAs by a non-canonical processing pathway

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685532

Action and reaction: the biological response to siRNA and its delivery vehicles

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685532

Production of virus-derived ping-pong-dependent piRNA-like small RNAs in the mosquito soma

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685532

In vivo delivery of cytoplasmic RNA virus-derived miRNAs

29 September 2017

1 reference

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West Nile virus encodes a microRNA-like small RNA in the 3' untranslated region which up-regulates GATA4 mRNA and facilitates virus replication in mosquito cells

29 September 2017

1 reference

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miRNA cassettes in viral vectors: problems and solutions

29 September 2017

1 reference

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Glycogen synthase kinase 3 beta (GSK3β) phosphorylates the RNAase III enzyme Drosha at S300 and S302

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685532

Implications of RNA virus-produced miRNAs

29 September 2017

1 reference

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Current prospects for RNA interference-based therapies

29 September 2017

1 reference

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Mosquito RNAi is the major innate immune pathway controlling arbovirus infection and transmission

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685532

Small RNA profiling of Dengue virus-mosquito interactions implicates the PIWI RNA pathway in anti-viral defense

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685532

Insertion of microRNA targets into the flavivirus genome alters its highly neurovirulent phenotype

29 September 2017

1 reference

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C6/36 Aedes albopictus Cells Have a Dysfunctional Antiviral RNA Interference Response

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685532

Comparison of dengue virus type 2-specific small RNAs from RNA interference-competent and -incompetent mosquito cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685532

Noncanonical cytoplasmic processing of viral microRNAs

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685532

Functional microRNA generated from a cytoplasmic RNA virus

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685532

Argonaute proteins are key determinants of RNAi efficacy, toxicity, and persistence in the adult mouse liver

29 September 2017

1 reference

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MicroRNA biogenesis via splicing and exosome-mediated trimming in Drosophila

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685532

Many ways to generate microRNA-like small RNAs: non-canonical pathways for microRNA production

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685532

Phosphorylation of the RNase III enzyme Drosha at Serine300 or Serine302 is required for its nuclear localization

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685532

Engineered RNA viral synthesis of microRNAs

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685532

Emerging paradigms of regulated microRNA processing

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685532

Viruses, microRNAs, and host interactions

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685532

Five questions about viruses and microRNAs

29 September 2017

1 reference

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Six RNA Viruses and Forty-One Hosts: Viral Small RNAs and Modulation of Small RNA Repertoires in Vertebrate and Invertebrate Systems

29 September 2017

1 reference

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A mammalian herpesvirus uses noncanonical expression and processing mechanisms to generate viral MicroRNAs

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685532

Filtering of deep sequencing data reveals the existence of abundant Dicer-dependent small RNAs derived from tRNAs

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685532

Characterization of viral and human RNAs smaller than canonical MicroRNAs

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685532

Small RNAs derived from snoRNAs

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685532

Suppression of RNA interference increases alphavirus replication and virus-associated mortality in Aedes aegypti mosquitoes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685532

Many roads to maturity: microRNA biogenesis pathways and their regulation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685532

Biogenesis of small RNAs in animals

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685532

Alphavirus-derived small RNAs modulate pathogenesis in disease vector mosquitoes

29 September 2017

1 reference

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A human snoRNA with microRNA-like functions

29 September 2017

1 reference

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Artificial microRNAs as siRNA shuttles: improved safety as compared to shRNAs in vitro and in vivo

29 September 2017

1 reference

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Mouse ES cells express endogenous shRNAs, siRNAs, and other Microprocessor-independent, Dicer-dependent small RNAs

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685532

McKusick's Online Mendelian Inheritance in Man (OMIM)

29 September 2017

1 reference

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RNAi therapeutics: an update on delivery

29 September 2017

1 reference

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Aedes aegypti uses RNA interference in defense against Sindbis virus infection

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685532

Construction and application of chimeric virus-like particles of tick-borne encephalitis virus and mosquito-borne Japanese encephalitis virus

29 September 2017

1 reference

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Epstein-Barr virus-encoded microRNA miR-BART2 down-regulates the viral DNA polymerase BALF5.

29 September 2017

1 reference

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Reduced levels of Ago2 expression result in increased siRNA competition in mammalian cells

29 September 2017

1 reference

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Designer gene delivery vectors: molecular engineering and evolution of adeno-associated viral vectors for enhanced gene transfer

29 September 2017

1 reference

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Production of Pseudoinfectious Yellow Fever Virus with a Two-Component Genome

29 September 2017

1 reference

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HIV-1 TAR element is processed by Dicer to yield a viral micro-RNA involved in chromatin remodeling of the viral LTR

29 September 2017

1 reference

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Intronic microRNA precursors that bypass Drosha processing

29 September 2017

1 reference

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Strategies for silencing human disease using RNA interference

29 September 2017

1 reference

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Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways

29 September 2017

1 reference

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Nuclear Localization of Flavivirus RNA Synthesis in Infected Cells

29 September 2017

1 reference

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Kunjin virus replicons: an RNA-based, non-cytopathic viral vector system for protein production, vaccine and gene therapy applications

29 September 2017

1 reference

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Second-generation shRNA libraries covering the mouse and human genomes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685532

Flavivirus Activates Phosphatidylinositol 3-Kinase Signaling To Block Caspase-Dependent Apoptotic Cell Death at the Early Stage of Virus Infection

29 September 2017

1 reference

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Gene therapy: twenty-first century medicine

29 September 2017

1 reference

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The Microprocessor complex mediates the genesis of microRNAs

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685532

Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685532

Tetracycline-inducible packaging cell line for production of flavivirus replicon particles

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685532

An alphavirus replicon particle chimera derived from venezuelan equine encephalitis and sindbis viruses is a potent gene-based vaccine delivery vector

29 September 2017

1 reference

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Progress and problems with the use of viral vectors for gene therapy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685532

Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685532

A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685532

Evaluation of recombinant alphaviruses as vectors in gene therapy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685532

Stable high-level expression of heterologous genes in vitro and in vivo by noncytopathic DNA-based Kunjin virus replicon vectors

29 September 2017

1 reference

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RNA viruses: emerging vectors for vaccination and gene therapy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685532

Stable alphavirus packaging cell lines for Sindbis virus and Semliki Forest virus-derived vectors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685532

Noncytopathic Sindbis virus RNA vectors for heterologous gene expression

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685532

Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685532

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685532

Construction and isolation of a transmissible retrovirus containing the src gene of Harvey murine sarcoma virus and the thymidine kinase gene of herpes simplex virus type 1

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685532

Adaptation of a Retrovirus as a Eucaryotic Vector Transmitting the Herpes Simplex Virus Thymidine Kinase Gene

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685532

Construction of Biologically Functional Bacterial Plasmids In Vitro

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685532

Biochemical method for inserting new genetic information into DNA of Simian Virus 40: circular SV40 DNA molecules containing lambda phage genes and the galactose operon of Escherichia coli

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685532

Formation of infectious progeny virus after insertion of herpes simplex thymidine kinase gene into DNA of an avian retrovirus

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685532

27 June 2018

Identifiers

DOI

10.1186/1743-422X-10-185

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23759022%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23759022%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

PubMed publication ID

23759022

1 reference