Modulation of 5-lipoxygenase in proteotoxicity and Alzheimer's disease (Q36938297)

17 August 2017

Modulation of 5-lipoxygenase in proteotoxicity and Alzheimer's disease (English)

1 reference

17 August 2017

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Elvira Valera

1

1 reference

17 August 2017

Richard Dargusch

series ordinal

2

1 reference

17 August 2017

Pamela A Maher

series ordinal

3

1 reference

17 August 2017

David Schubert

series ordinal

4

1 reference

17 August 2017

language of work or name

English

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publication date

1 June 2013

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17 August 2017

Journal of Neuroscience

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17 August 2017

33

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17 August 2017

25

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17 August 2017

10512-10525

1 reference

An alternative approach to drug discovery for Alzheimer's disease dementia

17 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3685841

Brain-specific disruption of the eIF2α kinase PERK decreases ATF4 expression and impairs behavioral flexibility.

29 September 2017

1 reference

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ER stress is involved in T17M rhodopsin-induced retinal degeneration.

29 September 2017

1 reference

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Clusterin in Alzheimer's disease

29 September 2017

1 reference

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A novel neurotrophic drug for cognitive enhancement and Alzheimer's disease

29 September 2017

1 reference

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Macromolecular and small-molecule modulation of intracellular Aβ42 aggregation and associated toxicity

29 September 2017

1 reference

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Impaired β-amyloid secretion in Alzheimer's disease pathogenesis

29 September 2017

1 reference

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The APP intracellular domain (AICD) potentiates ER stress-induced apoptosis

29 September 2017

1 reference

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Apomorphine treatment in Alzheimer mice promoting amyloid-β degradation

29 September 2017

1 reference

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Apomorphine and Alzheimer Aβ: roles for regulated α cleavage, autophagy, and antioxidation?

29 September 2017

1 reference

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Brain and spinal cord interaction: a dietary curcumin derivative counteracts locomotor and cognitive deficits after brain trauma

29 September 2017

1 reference

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Phospholipase d2 ablation ameliorates Alzheimer's disease-linked synaptic dysfunction and cognitive deficits

29 September 2017

1 reference

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Effects of synaptic modulation on beta-amyloid, synaptophysin, and memory performance in Alzheimer's disease transgenic mice.

29 September 2017

1 reference

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ADDLs and the signaling web that leads to Alzheimer's disease

29 September 2017

1 reference

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Activation of PERK signaling attenuates Abeta-mediated ER stress

29 September 2017

1 reference

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Induction of the unfolded protein response and cell death pathway in Alzheimer's disease, but not in aged Tg2576 mice

29 September 2017

1 reference

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Loss of HRD1-mediated protein degradation causes amyloid precursor protein accumulation and amyloid-beta generation

29 September 2017

1 reference

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Proteasome inhibitors activate autophagy as a cytoprotective response in human prostate cancer cells

29 September 2017

1 reference

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Basal levels of eIF2alpha phosphorylation determine cellular antioxidant status by regulating ATF4 and xCT expression

29 September 2017

1 reference

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Phospholipase A2 reduction ameliorates cognitive deficits in a mouse model of Alzheimer's disease

29 September 2017

1 reference

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A broadly neuroprotective derivative of curcumin

29 September 2017

1 reference

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Autophagy, amyloidogenesis and Alzheimer disease

29 September 2017

1 reference

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5-Lipoxygenase gene disruption reduces amyloid-beta pathology in a mouse model of Alzheimer's disease

29 September 2017

1 reference

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Heat shock proteins and amateur chaperones in amyloid-Beta accumulation and clearance in Alzheimer's disease

29 September 2017

1 reference

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Rodent A beta modulates the solubility and distribution of amyloid deposits in transgenic mice

29 September 2017

1 reference

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Intracellular amyloid-beta in Alzheimer's disease

29 September 2017

1 reference

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Brain-derived neurotrophic factor suppresses tunicamycin-induced upregulation of CHOP in neurons

29 September 2017

1 reference

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Combining the rapid MTT formazan exocytosis assay and the MC65 protection assay led to the discovery of carbazole analogs as small molecule inhibitors of Abeta oligomer-induced cytotoxicity

29 September 2017

1 reference

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A novel tricyclic pyrone compound ameliorates cell death associated with intracellular amyloid-beta oligomeric complexes

29 September 2017

1 reference

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Loss of autophagy in the central nervous system causes neurodegeneration in mice

29 September 2017

1 reference

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Environmental enrichment mitigates cognitive deficits in a mouse model of Alzheimer's disease

29 September 2017

1 reference

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Apolipoprotein E isoforms and apolipoprotein AI protect from amyloid precursor protein carboxy terminal fragment-associated cytotoxicity

29 September 2017

1 reference

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Oxytosis: A novel form of programmed cell death

29 September 2017

1 reference

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The activation of dopamine D4 receptors inhibits oxidative stress-induced nerve cell death.

29 September 2017

1 reference

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Regulation of antioxidant metabolism by translation initiation factor 2alpha

29 September 2017

1 reference

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Cytotoxicity mediated by conditional expression of a carboxyl-terminal derivative of the beta-amyloid precursor protein

29 September 2017

1 reference

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Intraneuronal beta-amyloid aggregates, neurodegeneration, and neuron loss in transgenic mice with five familial Alzheimer's disease mutations: potential factors in amyloid plaque formation.

29 September 2017

1 reference

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Phosphorylation by protein kinase a inhibits nuclear import of 5-lipoxygenase.

27 June 2018

1 reference

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Pro-brain-derived neurotrophic factor is decreased in parietal cortex in Alzheimer's disease.

27 June 2018

1 reference

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The substrate attached material synthesized by clonal cell lines of nerve, glia, and muscle.

27 June 2018

1 reference

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Soluble Aβ levels correlate with cognitive deficits in the 12-month-old APPswe/PS1dE9 mouse model of Alzheimer's disease.

27 June 2018

1 reference

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A pyrazole derivative of curcumin enhances memory

4 September 2018

1 reference

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Promoting basal levels of autophagy in the nervous system enhances longevity and oxidant resistance in adult Drosophila

4 September 2018

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The role of brain-derived neurotrophic factor (BDNF)-induced XBP1 splicing during brain development.

4 September 2018

1 reference

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Heat shock proteins 70 and 90 inhibit early stages of amyloid beta-(1-42) aggregation in vitro.

4 September 2018

1 reference

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Temporal profile of amyloid-beta (Abeta) oligomerization in an in vivo model of Alzheimer disease. A link between Abeta and tau pathology

4 September 2018

1 reference

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Intraneuronal Abeta causes the onset of early Alzheimer's disease-related cognitive deficits in transgenic mice

4 September 2018

1 reference

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Intraneuronal Abeta accumulation precedes plaque formation in beta-amyloid precursor protein and presenilin-1 double-transgenic mice.

4 September 2018

1 reference

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NMDA receptor stimulation and brain-derived neurotrophic factor upregulate homer 1a mRNA via the mitogen-activated protein kinase cascade in cultured cerebellar granule cells.

4 September 2018

1 reference

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Transgenic mice with Alzheimer presenilin 1 mutations show accelerated neurodegeneration without amyloid plaque formation.

4 September 2018

1 reference

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Oxidative stress increases levels of endogenous amyloid-beta peptides secreted from primary chick brain neurons

4 September 2018

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12 December 2020

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The regulatory mechanism of Hsp90alpha secretion from endothelial cells and its role in angiogenesis during wound healing

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PubMed

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Inflammatory 5-LOX mRNA and protein are increased in brain of aging rats

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inferred from PubMed ID database lookup

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Identifiers

DOI

10.1523/JNEUROSCI.5183-12.2013

1 reference

17 August 2017

1 reference

17 August 2017

1 reference