Mutations M184V and Y115F in HIV-1 reverse transcriptase discriminate against "nucleotide-competing reverse transcriptase inhibitors". (Q36949351)

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12 January 2020

title

Mutations M184V and Y115F in HIV-1 reverse transcriptase discriminate against "nucleotide-competing reverse transcriptase inhibitors" (English)

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12 January 2020

4

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12 January 2020

Dirk Jochmans

7

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12 January 2020

author name string

Maryam Ehteshami

1

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12 January 2020

Brian J Scarth

2

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Egor P Tchesnokov

3

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12 January 2020

Stuart F J Le Grice

5

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12 January 2020

Sabine Hallenberger

6

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12 January 2020

Matthias Götte

8

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language of work or name

English

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publication date

25 August 2008

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Journal of Biological Chemistry

12 January 2020

published in

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volume

283

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issue

44

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page(s)

29904-29911

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describes a project that uses

12 January 2020

ImageQuant

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11 June 2022

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Probing the active site steric flexibility of HIV-1 reverse transcriptase: different constraints for DNA- versus RNA-templated synthesis

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Analysis of HIV-1 replication block due to substitutions at F61 residue of reverse transcriptase reveals additional defects involving the RNase H function

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Structure of a covalently trapped catalytic complex of HIV-1 reverse transcriptase: implications for drug resistance

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Human immunodeficiency virus type 1 reverse transcriptase: role of Tyr115 in deoxynucleotide binding and misinsertion fidelity of DNA synthesis

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Comparison of deoxyoligonucleotide and tRNA(Lys-3) as primers in an endogenous human immunodeficiency virus-1 in vitro reverse transcription/template-switching reaction

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PubMed

https://pubmed.ncbi.nlm.nih.gov/18728003

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12 December 2020

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Identifiers

DOI

10.1074/JBC.M804882200

1 reference

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12 January 2020

1 reference

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12 January 2020

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