Synergistic effects of Pten loss and WNT/CTNNB1 signaling pathway activation in ovarian granulosa cell tumor development and progression. (Q36959003)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18687666%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

title

Synergistic effects of Pten loss and WNT/CTNNB1 signaling pathway activation in ovarian granulosa cell tumor development and progression (English)

1 reference

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ovarian granulosa cell tumor

11 January 2020

main subject

1 reference

5

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11 January 2020

Soazik P Jamin

6

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11 January 2020

Peter J. Fuller

8

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11 January 2020

author name string

Marie-Noëlle Laguë

1

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11 January 2020

Marilène Paquet

2

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11 January 2020

Heng-Yu Fan

3

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11 January 2020

M Johanna Kaartinen

4

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11 January 2020

Richard R Behringer

7

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11 January 2020

Andrew Mitchell

9

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11 January 2020

Monique Doré

10

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11 January 2020

Louis M Huneault

11

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11 January 2020

Joanne S Richards

12

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11 January 2020

Derek Boerboom

13

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11 January 2020

language of work or name

English

0 references

publication date

6 August 2008

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11 January 2020

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11 January 2020

volume

29

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11 January 2020

issue

11

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11 January 2020

page(s)

2062-2072

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Selective expression of KrasG12D in granulosa cells of the mouse ovary causes defects in follicle development and ovulation

11 January 2020

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Clinical and pathological predictive factors in women with adult-type granulosa cell tumor of the ovary

29 September 2017

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29 September 2017

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FSH signaling pathways in immature granulosa cells that regulate target gene expression: branching out from protein kinase A.

29 September 2017

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Beyond PTEN mutations: the PI3K pathway as an integrator of multiple inputs during tumorigenesis

29 September 2017

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PTEN and GSK3beta: key regulators of progression to androgen-independent prostate cancer

29 September 2017

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PTEN function in normal and neoplastic growth

29 September 2017

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Epithelial-mesenchymal transition in development and cancer: role of phosphatidylinositol 3' kinase/AKT pathways

29 September 2017

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Akt: versatile mediator of cell survival and beyond

29 September 2017

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Granulosa cell tumour: a recurrence 40 years after initial diagnosis

29 September 2017

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Wnt signaling in disease and in development

29 September 2017

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Proteasomal degradation of the FoxO1 transcriptional regulator in cells transformed by the P3k and Akt oncoproteins

29 September 2017

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Insulin and wnt1 pathways cooperate to induce reserve cell activation in differentiation and myotube hypertrophy

29 September 2017

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Transrepression of estrogen receptor beta signaling by nuclear factor-kappab in ovarian granulosa cells

29 September 2017

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Signalling pathways in the molecular pathogenesis of ovarian granulosa cell tumours

29 September 2017

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Granulosa cell-specific inactivation of follistatin causes female fertility defects.

29 September 2017

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Stabilization of beta-catenin by a Wnt-independent mechanism regulates cardiomyocyte growth

29 September 2017

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Granulosa cell tumor of the ovary

29 September 2017

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Requirement of Bmpr1a for Müllerian duct regression during male sexual development

29 September 2017

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The phosphatidylinositol 3-Kinase AKT pathway in human cancer

29 September 2017

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Intestinal polyposis in mice with a dominant stable mutation of the beta-catenin gene

29 September 2017

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29 September 2017

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Molecular characterization of equine prostaglandin G/H synthase-2 and regulation of its messenger ribonucleic acid in preovulatory follicles

29 September 2017

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A mutation in the follicle-stimulating hormone receptor occurs frequently in human ovarian sex cord tumors

29 September 2017

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Absence of the previously reported G protein oncogene (gip2) in ovarian granulosa cell tumors

29 September 2017

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Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

29 September 2017

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Targeted overexpression of luteinizing hormone in transgenic mice leads to infertility, polycystic ovaries, and ovarian tumors.

29 September 2017

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Hormonal control of gene expression in the ovary

29 September 2017

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Alpha-inhibin is a tumour-suppressor gene with gonadal specificity in mice

29 September 2017

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Follicle-stimulating hormone induction of ovarian insulin-like growth factor-binding protein-3 transcription requires a TATA box-binding protein and the protein kinase A and phosphatidylinositol-3 kinase pathways

29 September 2017

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Expression of FKHR, FKHRL1, and AFX genes in the rodent ovary: evidence for regulation by IGF-I, estrogen, and the gonadotropins

27 June 2018

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Activating mutation of the stimulatory G protein (gsp) as a putative cause of ovarian and testicular human stromal Leydig cell tumors.

27 June 2018

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Gonadal tumorigenesis in transgenic mice bearing the mouse inhibin alpha-subunit promoter/simian virus T-antigen fusion gene: characterization of ovarian tumors and establishment of gonadotropin-responsive granulosa cell lines

27 June 2018

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Granulosa cell maturation in the rat: increased binding of human chorionic gonadotropin following treatment with follicle-stimulating hormone in vivo

27 June 2018

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Misregulated Wnt/beta-catenin signaling leads to ovarian granulosa cell tumor development.

27 June 2018

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Overexpression of the tumor suppressor gene phosphatase and tensin homologue partially inhibits wnt-1-induced mammary tumorigenesis

4 September 2018

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Phosphatidylinositol 3-kinase-Akt pathway plays a critical role in early cardiomyogenesis by regulating canonical Wnt signaling

4 September 2018

1 reference

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Cell-nonautonomous induction of ovarian and uterine serous cystadenomas in mice lacking a functional Brca1 in ovarian granulosa cells

4 September 2018

1 reference

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Expression status and mutational analysis of the ras and B-raf genes in ovarian granulosa cell and epithelial tumors.

4 September 2018

1 reference

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Endothelial and steroidogenic cell migration are regulated by WNT4 in the developing mammalian gonad.

4 September 2018

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Negative regulation of neural stem/progenitor cell proliferation by the Pten tumor suppressor gene in vivo.

4 September 2018

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Signal transduction: signaling specificity- a complex affair

4 September 2018

1 reference

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No evidence of somatic activating mutations on gonadotropin receptor genes in sex cord stromal tumors.

4 September 2018

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Insulin-like growth factor, insulin-like growth factor?binding protein-4, and pregnancy-associated plasma protein-A gene expression in human granulosa cell tumors

4 September 2018

1 reference

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Follicle-Stimulating Hormone (FSH) Stimulates Phosphorylation and Activation of Protein Kinase B (PKB/Akt) and Serum and Glucocorticoid-Induced Kinase (Sgk): Evidence for A Kinase-Independent Signaling by FSH in Granulosa Cells

4 December 2018

1 reference

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Comment on analysis of mutations in genes of the follicle-stimulating hormone receptor in ovarian granulosa cell tumors

4 December 2018

1 reference

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Induction of prostaglandin endoperoxide synthase-2 by human chorionic gonadotropin in bovine preovulatory follicles in vivo

4 December 2018

1 reference

12 December 2020

No evidence of a role for mutations or polymorphisms of the follicle-stimulating hormone receptor in ovarian granulosa cell tumors

1 reference

12 December 2020

Analysis of mutations in genes of the follicle-stimulating hormone receptor signaling pathway in ovarian granulosa cell tumors

1 reference

12 December 2020

Generation of tumors in transgenic mice expressing the SV40 T antigen under the control of ovarian-specific promoter 1

1 reference

12 December 2020

Trophoblast apoptosis is inhibited by hepatocyte growth factor through the Akt and β-catenin mediated up-regulation of inducible nitric oxide synthase

1 reference

12 December 2020

Bridging the BMP and Wnt pathways by PI3 kinase/Akt and 14-3-3zeta

1 reference

12 December 2020

Conditional deletion of beta-catenin in the mesenchyme of the developing mouse uterus results in a switch to adipogenesis in the myometrium

1 reference

12 December 2020

Dominant-stable beta-catenin expression causes cell fate alterations and Wnt signaling antagonist expression in a murine granulosa cell tumor model

1 reference

12 December 2020

Follicle-stimulating hormone induces multiple signaling cascades: evidence that activation of Rous sarcoma oncogene, RAS, and the epidermal growth factor receptor are critical for granulosa cell differentiation

1 reference

12 December 2020

Estrogen receptor isoform gene expression in ovarian stromal and epithelial tumors

1 reference

12 December 2020

Insulin and IGF-1 stimulate the beta-catenin pathway through two signalling cascades involving GSK-3beta inhibition and Ras activation

1 reference

12 December 2020

Insulin-like growth factor-1 induces survival and growth of biologically early melanoma cells through both the mitogen-activated protein kinase and beta-catenin pathways

1 reference

12 December 2020

Identifiers

DOI

10.1093/CARCIN/BGN186

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18687666%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18687666%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

1 reference