PTEN and GSK3beta: key regulators of progression to androgen-independent prostate cancer (Q28292541)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16421604%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

review article

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title

PTEN and GSK3beta: key regulators of progression to androgen-independent prostate cancer (English)

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15 January 2020

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2

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15 January 2020

author name string

D J Mulholland

series ordinal

1

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15 January 2020

H Wu

series ordinal

3

1 reference

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15 January 2020

C C Nelson

series ordinal

4

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15 January 2020

language of work or name

English

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publication date

1 January 2006

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15 January 2020

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15 January 2020

volume

25

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15 January 2020

issue

3

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15 January 2020

page(s)

329-337

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Activation of beta-catenin in prostate epithelium induces hyperplasias and squamous transdifferentiation

15 January 2020

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Increased insulin-like growth factor I receptor expression and signaling are components of androgen-independent progression in a lineage-derived prostate cancer progression model

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Akt suppresses androgen-induced apoptosis by phosphorylating and inhibiting androgen receptor

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Recruitment of beta-catenin by wild-type or mutant androgen receptors correlates with ligand-stimulated growth of prostate cancer cells

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Bicalutamide (Casodex)-induced prostate regression involves increased expression of genes encoding insulin-like growth factor binding proteins

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Liganded androgen receptor interaction with beta-catenin: nuclear co-localization and modulation of transcriptional activity in neuronal cells

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Inhibition of integrin-linked kinase (ILK) suppresses activation of protein kinase B/Akt and induces cell cycle arrest and apoptosis of PTEN-mutant prostate cancer cells

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Regulation of protein kinase B/Akt-serine 473 phosphorylation by integrin-linked kinase: critical roles for kinase activity and amino acids arginine 211 and serine 343

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Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

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Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers

21 April 2017

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The transcriptional coactivator CBP interacts with beta-catenin to activate gene expression

21 April 2017

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Prostate-specific deletion of the murine Pten tumor suppressor gene leads to metastatic prostate cancer

21 April 2017

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Evidence for regulation of the PTEN tumor suppressor by a membrane-localized multi-PDZ domain containing scaffold protein MAGI-2

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Linking beta-catenin to androgen-signaling pathway

21 April 2017

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Cloning and characterization of a specific coactivator, ARA70, for the androgen receptor in human prostate cells

21 April 2017

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The phosphatidylinositol 3-Kinase AKT pathway in human cancer

21 April 2017

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Wnt proteins are lipid-modified and can act as stem cell growth factors

21 April 2017

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Androgen receptor regulates expression of skeletal muscle-specific proteins and muscle cell types

21 April 2017

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7 January 2021

Expression of potential beta-catenin targets, cyclin D1, c-Jun, c-Myc, E-cadherin, and EGFR in chemically induced hepatocellular neoplasms from B6C3F1 mice.

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7 January 2021

Deletion, methylation, and expression of the NKX3.1 suppressor gene in primary human prostate cancer

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7 January 2021

Myc confers androgen-independent prostate cancer cell growth

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7 January 2021

Promoter deletion and loss of retinoblastoma gene expression in human prostate carcinoma

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7 January 2021

Up-regulation of Wnt-1 and beta-catenin production in patients with advanced metastatic prostate carcinoma: potential pathogenetic and prognostic implications.

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7 January 2021

In vitro evidence for complex modes of nuclear beta-catenin signaling during prostate growth and tumorigenesis

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7 January 2021

Post-transcriptional regulation of the androgen receptor by Mammalian target of rapamycin

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7 January 2021

The transcriptional co-activator cAMP response element-binding protein-binding protein is expressed in prostate cancer and enhances androgen- and anti-androgen-induced androgen receptor function

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7 January 2021

Differential regulation of glycogen synthase kinase 3beta by insulin and Wnt signaling

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7 January 2021

PI 3-kinase, Akt and cell survival

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7 January 2021

Reduction of PTEN and p27kip1 expression correlates with tumor grade in prostate cancer. Analysis in radical prostatectomy specimens and needle biopsies.

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7 January 2021

Myc-driven murine prostate cancer shares molecular features with human prostate tumors

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7 January 2021

Acetylation of androgen receptor enhances coactivator binding and promotes prostate cancer cell growth

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7 January 2021

Nuclear receptor modifications and endocrine cell proliferation

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7 January 2021

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7 January 2021

Role of PI3K/AKT/mTOR signaling in the cell cycle progression of human prostate cancer

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7 January 2021

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7 January 2021

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Stabilization of beta-catenin induces lesions reminiscent of prostatic intraepithelial neoplasia, but terminal squamous transdifferentiation of other secretory epithelia

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7 January 2021

Increased AKT activity contributes to prostate cancer progression by dramatically accelerating prostate tumor growth and diminishing p27Kip1 expression

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7 January 2021

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A novel human prostate-specific, androgen-regulated homeobox gene (NKX3.1) that maps to 8p21, a region frequently deleted in prostate cancer

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7 January 2021

Androgen-dependent cell cycle arrest and apoptotic death in PC-3 prostatic cell cultures expressing a full-length human androgen receptor

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7 January 2021

Androgens negatively regulate forkhead transcription factor FKHR (FOXO1) through a proteolytic mechanism in prostate cancer cells

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7 January 2021

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7 January 2021

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7 January 2021

Prostate specific antigen gene regulation by androgen receptor

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7 January 2021

The assessment of PTEN tumor suppressor gene in combination with Gleason scoring and serum PSA to evaluate progression of prostate carcinoma.

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7 January 2021

Phosphorylation of Akt (Ser473) is an excellent predictor of poor clinical outcome in prostate cancer.

1 reference

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7 January 2021

Synergistic effects of coactivators GRIP1 and beta-catenin on gene activation: cross-talk between androgen receptor and Wnt signaling pathways

1 reference

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7 January 2021

Antagonism between PTEN/MMAC1/TEP-1 and androgen receptor in growth and apoptosis of prostatic cancer cells

1 reference

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7 January 2021

Glycogen synthase kinase-3beta activity is required for androgen-stimulated gene expression in prostate cancer

1 reference

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7 January 2021

Suppression versus induction of androgen receptor functions by the phosphatidylinositol 3-kinase/Akt pathway in prostate cancer LNCaP cells with different passage numbers.

1 reference

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7 January 2021

Carboxyl-terminal modulator protein (CTMP), a negative regulator of PKB/Akt and v-Akt at the plasma membrane

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7 January 2021

mTOR inhibition reverses Akt-dependent prostate intraepithelial neoplasia through regulation of apoptotic and HIF-1-dependent pathways

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7 January 2021

Prostate intraepithelial neoplasia induced by prostate restricted Akt activation: the MPAKT model

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7 January 2021

Prostate cancer incidence and mortality rates and trends in the United States and Canada

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7 January 2021

Pharmacological inhibitors of glycogen synthase kinase 3.

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7 January 2021

The androgen axis in recurrent prostate cancer

1 reference

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7 January 2021

The androgen receptor can promote beta-catenin nuclear translocation independently of adenomatous polyposis coli

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7 January 2021

Role of PI3K signaling in survival and progression of LNCaP prostate cancer cells to the androgen refractory state

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7 January 2021

The PTEN tumor suppressor is a negative modulator of androgen receptor transcriptional activity

1 reference

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7 January 2021

A C619Y mutation in the human androgen receptor causes inactivation and mislocalization of the receptor with concomitant sequestration of SRC-1 (steroid receptor coactivator 1)

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7 January 2021

Molecular modeling in the design of peptidomimetics and peptide surrogates

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7 January 2021

Tumor suppressor PTEN inhibits nuclear accumulation of beta-catenin and T cell/lymphoid enhancer factor 1-mediated transcriptional activation

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7 January 2021

Loss of heterozygosity of the retinoblastoma and adenomatous polyposis susceptibility gene loci and in chromosomes 10p, 10q and 16q in human prostate cancer

1 reference

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7 January 2021

PTEN induces cell cycle arrest by decreasing the level and nuclear localization of cyclin D1.

1 reference

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7 January 2021

Tamm-Horsfall glycoprotein links innate immune cell activation with adaptive immunity via a toll-like receptor-4-dependent mechanism

1 reference

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7 January 2021

Glycogen synthase kinase-3 beta is involved in the phosphorylation and suppression of androgen receptor activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209020

7 January 2021

Phosphatidylinositol 3-kinase/Akt stimulates androgen pathway through GSK3beta inhibition and nuclear beta-catenin accumulation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209020

7 January 2021

Evidence for down-regulation of phosphoinositide 3-kinase/Akt/mammalian target of rapamycin (PI3K/Akt/mTOR)-dependent translation regulatory signaling pathways in Ames dwarf mice

1 reference

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7 January 2021

Beta-catenin binds to the activation function 2 region of the androgen receptor and modulates the effects of the N-terminal domain and TIF2 on ligand-dependent transcription

1 reference

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7 January 2021

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209020

1 reference

7 January 2021

Synergy in tumor suppression by direct interaction of Neutral Endopeptidase with PTEN

1 reference

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7 January 2021

Regulation of tumor angiogenesis by integrin-linked kinase (ILK).

1 reference

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7 January 2021

Mammalian target of rapamycin and 3-phosphatidylinositol 3-kinase pathway inhibition enhances growth inhibition of transforming growth factor-beta1 in prostate cancer cells

1 reference

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7 January 2021

You Wnt some, you lose some: oncogenes in the Wnt signaling pathway

1 reference

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7 January 2021

Wnt3a growth factor induces androgen receptor-mediated transcription and enhances cell growth in human prostate cancer cells.

1 reference

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7 January 2021

Beta-catenin is involved in insulin-like growth factor 1-mediated transactivation of the androgen receptor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209020

7 January 2021

Interleukin-6 inhibits the growth of prostate cancer xenografts in mice by the process of neuroendocrine differentiation

1 reference

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7 January 2021

Phosphorylation of androgen receptor isoforms

1 reference

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7 January 2021

Effects of the mammalian target of rapamycin inhibitor CCI-779 used alone or with chemotherapy on human prostate cancer cells and xenografts

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7 January 2021

In vivo regeneration of murine prostate from dissociated cell populations of postnatal epithelia and urogenital sinus mesenchyme

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7 January 2021

Prostatic neoplasia in transgenic mice with prostate-directed overexpression of the c-myc oncoprotein

1 reference

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7 January 2021

PTEN inhibits cell proliferation and induces apoptosis by downregulating cell surface IGF-IR expression in prostate cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209020

7 January 2021

Analysis of Wnt gene expression in prostate cancer: mutual inhibition by WNT11 and the androgen receptor

1 reference

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7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1209020

2 references

Consolidated OpenCitations Corpus – April 2017

4279108

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Dimensions Publication ID

15 January 2020

1016164983

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Fatcat ID

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24 November 2022

mapped directly with Wikidata item

4279108

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Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

2 references

4279108

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16421604%20AND%20SRC:MED&resulttype=core&format=json