Genetics and epigenetics of the multifunctional protein CTCF. (Q36976477)

17 August 2017

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title

Genetics and epigenetics of the multifunctional protein CTCF. (English)

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17 August 2017

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Galina N Filippova

1

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17 August 2017

1 January 2008

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Current Topics in Developmental Biology

17 August 2017

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17 August 2017

80

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17 August 2017

337-360

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The insulator protein CTCF represses transcription on binding to the (gt)(22)(ga)(15) microsatellite in intron 2 of the HLA-DRB1(*)0401 gene

17 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

Negative transcriptional regulation mediated by thyroid hormone response element 144 requires binding of the multivalent factor CTCF to a novel target DNA sequence

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

High-resolution profiling of histone methylations in the human genome

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

Mechanisms underlying epigenetically mediated gene silencing in cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

Epigenetic gene silencing in cancer – a mechanism for early oncogenic pathway addiction?

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

Methylation of a CTCF-dependent boundary controls imprinted expression of the Igf2 gene

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

The protein CTCF is required for the enhancer blocking activity of vertebrate insulators

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

Insulators and boundaries: versatile regulatory elements in the eukaryotic genome

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

CTCF regulates asynchronous replication of the imprinted H19/Igf2 domain

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

Negative protein 1, which is required for function of the chicken lysozyme gene silencer in conjunction with hormone receptors, is identical to the multivalent zinc finger repressor CTCF.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

Molecular cloning and expression of the chromatin insulator protein CTCF in Xenopus laevis.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

CTCF binding and higher order chromatin structure of the H19 locus are maintained in mitotic chromatin

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

Epigenetic inactivation of BRCA1 is associated with aberrant expression of CTCF and DNA methyltransferase (DNMT3B) in some sporadic breast tumours.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

DNA binding sites for putative methylation boundaries in the unmethylated region of the BRCA1 promoter.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

BRCA1 methylation: a significant role in tumour development?

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

Chromatin of the Barr body: histone and non-histone proteins associated with or excluded from the inactive X chromosome.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

CTCF, a candidate trans-acting factor for X-inactivation choice

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

CTCF interacts with and recruits the largest subunit of RNA polymerase II to CTCF target sites genome-wide

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

Physical and functional interaction between two pluripotent proteins, the Y-box DNA/RNA-binding factor, YB-1, and the multivalent zinc finger factor, CTCF

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https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

Antisense transcription and heterochromatin at the DM1 CTG repeats are constrained by CTCF.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

Physical basis of a protein-DNA recognition code

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

At least two different regions are involved in allelic imbalance on chromosome arm 16q in breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

Comprehensive Genome Sequence Analysis of a Breast Cancer Amplicon

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

The human enhancer blocker CTC-binding factor interacts with the transcription factor Kaiso

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

Capturing chromosome conformation

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

Epigenetic regulation of the human retinoblastoma tumor suppressor gene promoter by CTCF

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

Escape from X inactivation

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https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

Heightened expression of CTCF in breast cancer cells is associated with resistance to apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

Identification of a Ctcf cofactor, Yy1, for the X chromosome binary switch.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

The insulator binding protein CTCF associates with the nuclear matrix

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https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

CTCF binding sites promote transcription initiation and prevent DNA methylation on the maternal allele at the imprinted H19/Igf2 locus

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

Epigenetics provides a new generation of oncogenes and tumour-suppressor genes

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

Cancer epigenomics: DNA methylomes and histone-modification maps

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

Transgenic RNAi reveals essential function for CTCF in H19 gene imprinting

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

Cancer epigenetics takes center stage.

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https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

Hypomethylation distinguishes genes of some human cancers from their normal counterparts

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

DNA methylation and genomic imprinting: insights from cancer into epigenetic mechanisms

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

The epigenetic progenitor origin of human cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

An exceptionally conserved transcriptional repressor, CTCF, employs different combinations of zinc fingers to bind diverged promoter sequences of avian and mammalian c-myc oncogenes

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

A widely expressed transcription factor with multiple DNA sequence specificity, CTCF, is localized at chromosome segment 16q22.1 within one of the smallest regions of overlap for common deletions in breast and prostate cancers

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

CTCF-binding sites flank CTG/CAG repeats and form a methylation-sensitive insulator at the DM1 locus

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

Boundaries between chromosomal domains of X inactivation and escape bind CTCF and lack CpG methylation during early development

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

Allele-specific binding of CTCF to the multipartite imprinting control region KvDMR1

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

High-resolution integrated map encompassing the breast cancer loss of heterozygosity region on human chromosome 16q22.1.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

Insulators: exploiting transcriptional and epigenetic mechanisms

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

A chromatin insulator determines the nuclear localization of DNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

Chromatin insulators and boundaries: effects on transcription and nuclear organization

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

Cloning and characterization of cDNAs encoding putative CTCFs in the mosquitoes, Aedes aegypti and Anopheles gambiae

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

CTCF mediates methylation-sensitive enhancer-blocking activity at the H19/Igf2 locus

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

CpG methylation regulates the Igf2/H19 insulator

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https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

CTCF-dependent chromatin insulator is linked to epigenetic remodeling

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https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

CpG island methylator phenotype in cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

The testis-specific factor CTCFL cooperates with the protein methyltransferase PRMT7 in H19 imprinting control region methylation

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

DNA methylation and cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

Functional association of CTCF with the insulator upstream of the H19 gene is parent of origin-specific and methylation-sensitive

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

Multiple nucleosome positioning sites regulate the CTCF-mediated insulator function of the H19 imprinting control region

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

Analysis of the vertebrate insulator protein CTCF-binding sites in the human genome

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

Poly(ADP-ribosyl)ation and epigenetics. Is CTCF PARt of the plot?

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

CTCF, a conserved nuclear factor required for optimal transcriptional activity of the chicken c-myc gene, is an 11-Zn-finger protein differentially expressed in multiple forms

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

Functional phosphorylation sites in the C-terminal region of the multivalent multifunctional transcriptional factor CTCF

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

The novel BORIS + CTCF gene family is uniquely involved in the epigenetics of normal biology and cancer

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https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

Raising the curtains on interchromosomal interactions

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https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

CTCF binding at the H19 imprinting control region mediates maternally inherited higher-order chromatin conformation to restrict enhancer access to Igf2

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

Genomic imprinting: CTCF protects the boundaries

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

CTCF mediates interchromosomal colocalization between Igf2/H19 and Wsb1/Nf1.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

Escape from X inactivation of Smcx is preceded by silencing during mouse development

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

BORIS, a novel male germ-line-specific protein associated with epigenetic reprogramming events, shares the same 11-zinc-finger domain with CTCF, the insulator protein involved in reading imprinting marks in the soma

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

Thyroid hormone-regulated enhancer blocking: cooperation of CTCF and thyroid hormone receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

The profile of repeat-associated histone lysine methylation states in the mouse epigenome

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

CTCF is conserved from Drosophila to humans and confers enhancer blocking of the Fab-8 insulator

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

The binding sites for the chromatin insulator protein CTCF map to DNA methylation-free domains genome-wide

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

Association of chromosome arm 16q loss with loss of imprinting of insulin-like growth factor-II in Wilms tumor.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

Interaction between differentially methylated regions partitions the imprinted genes Igf2 and H19 into parent-specific chromatin loops

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

Tsix-mediated epigenetic switch of a CTCF-flanked region of the Xist promoter determines the Xist transcription program

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

Relaxation of insulin-like growth factor II gene imprinting implicated in Wilms' tumour

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

Triplet repeat expansion in myotonic dystrophy alters the adjacent chromatin structure

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

Mutation of a single CTCF target site within the H19 imprinting control region leads to loss of Igf2 imprinting and complex patterns of de novo methylation upon maternal inheritance.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

Familial cases of point mutations in the XIST promoter reveal a correlation between CTCF binding and pre-emptive choices of X chromosome inactivation

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

Cloning and characterization of zebrafish CTCF: Developmental expression patterns, regulation of the promoter region, and evolutionary aspects of gene organization

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

High-resolution analysis of 16q22.1 in breast carcinoma using DNA amplifiable probes (multiplex amplifiable probe hybridization technique) and immunohistochemistry

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

Position-effect protection and enhancer blocking by the chicken beta-globin insulator are separable activities

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

The complex pathology of trinucleotide repeats

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

CTCF binds the proximal exonic region of hTERT and inhibits its transcription

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

Loss of imprinting of Igf2 alters intestinal maturation and tumorigenesis in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

CTCF maintains differential methylation at the Igf2/H19 locus

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

Molecular biology. Managing associations between different chromosomes

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

CTCF mediates long-range chromatin looping and local histone modification in the beta-globin locus

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

Spreading of silent chromatin: inaction at a distance

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

Perturbations of the Ink4a/Arf gene locus in aflatoxin B1-induced mouse lung tumors.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

Deconstructing myotonic dystrophy

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

Genomic imprinting and cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

Conditional expression of the CTCF-paralogous transcriptional factor BORIS in normal cells results in demethylation and derepression of MAGE-A1 and reactivation of other cancer-testis genes

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

The zinc finger protein CTCF binds to the APBbeta domain of the amyloid beta-protein precursor promoter. Evidence for a role in transcriptional activation

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

Insulators: many functions, many mechanisms.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

CTCF is essential for up-regulating expression from the amyloid precursor protein promoter during differentiation of primary hippocampal neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

Chromosome arm 16q in Wilms tumors: unbalanced chromosomal translocations, loss of heterozygosity, and assessment of the CTCF gene.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

Rasgrf1 imprinting is regulated by a CTCF-dependent methylation-sensitive enhancer blocker

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

Poly(ADP-ribosyl)ation regulates CTCF-dependent chromatin insulation.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

The 5'-HS4 chicken beta-globin insulator is a CTCF-dependent nuclear matrix-associated element

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

CTCF tethers an insulator to subnuclear sites, suggesting shared insulator mechanisms across species

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

An insulator blocks spreading of histone acetylation and interferes with RNA polymerase II transfer between an enhancer and gene

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

A screen for germline mutations in the gene encoding CCCTC-binding factor (CTCF) in familial non-BRCA1/BRCA2 breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980009-3

7 January 2021

10.1016/S0070-2153(07)80009-3

Identifiers

DOI

1 reference

release_qq3vvn5wtndqddj3f4osldj22e

17 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/qq3vvn5wtndqddj3f4osldj22e

24 November 2022

mapped directly with Wikidata item

PubMed ID

17950379

1 reference

PubMed ID

17950379