BRCA1 methylation: a significant role in tumour development? (Q34793004)

4 August 2017

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title

BRCA1 methylation: a significant role in tumour development? (English)

1 reference

4 August 2017

Aurélie Catteau

1

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PubMed ID

12191635

4 August 2017

Joanna R Morris

series ordinal

2

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4 August 2017

1 October 2002

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Seminars in Cancer Biology

4 August 2017

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4 August 2017

12

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4 August 2017

5

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4 August 2017

359-371

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A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1

4 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

7 January 2021

Confirmation of BRCA1 by analysis of germline mutations linked to breast and ovarian cancer in ten families

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

7 January 2021

Genetic heterogeneity and penetrance analysis of the BRCA1 and BRCA2 genes in breast cancer families. The Breast Cancer Linkage Consortium

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

7 January 2021

Germ line mutations associated with breast cancer susceptibility

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

7 January 2021

Somatic mutations in the BRCA1 gene in sporadic ovarian tumours.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

7 January 2021

Allele losses in the region 17q12-21 in familial breast and ovarian cancer involve the wild-type chromosome

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

7 January 2021

Cancer susceptibility and the functions of BRCA1 and BRCA2

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

7 January 2021

New complexities for BRCA1 and BRCA2.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

7 January 2021

A targeted disruption of the murine Brca1 gene causes gamma-irradiation hypersensitivity and genetic instability.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

7 January 2021

Gamma-rays-induced death of human cells carrying mutations of BRCA1 or BRCA2

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

7 January 2021

Conditional mutation of Brca1 in mammary epithelial cells results in blunted ductal morphogenesis and tumour formation.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

7 January 2021

Brca1 controls homology-directed DNA repair

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

7 January 2021

Direct DNA binding by Brca1

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

7 January 2021

p53 mutations in BRCA1-associated familial breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

7 January 2021

Genetic interactions between tumor suppressors Brca1 and p53 in apoptosis, cell cycle and tumorigenesis.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

7 January 2021

Transcriptional activation by BRCA1

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

7 January 2021

Evidence for a transcriptional activation function of BRCA1 C-terminal region

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

7 January 2021

Sequence-specific transcriptional corepressor function for BRCA1 through a novel zinc finger protein, ZBRK1

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

7 January 2021

BRCA1 regulates p53-dependent gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

7 January 2021

BRCA1 Inhibition of Estrogen Receptor Signaling in Transfected Cells

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

7 January 2021

A mechanism for exon skipping caused by nonsense or missense mutations in BRCA1 and other genes

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

7 January 2021

Complete genomic sequence and analysis of 117 kb of human DNA containing the gene BRCA1

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

7 January 2021

BRCA1 genomic deletions are major founder mutations in Dutch breast cancer patients

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

7 January 2021

Screening for genomic rearrangements in families with breast and ovarian cancer identifies BRCA1 mutations previously missed by conformation-sensitive gel electrophoresis or sequencing

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

7 January 2021

Identification of a large rearrangement of the BRCA1 gene using colour bar code on combed DNA in an American breast/ovarian cancer family previously studied by direct sequencing

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

7 January 2021

BRCA1 mutations in primary breast and ovarian carcinomas.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

7 January 2021

A somatic BRCA1 mutation in an ovarian tumour.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

7 January 2021

Somatic mutations in the BRCA1 gene in Chinese sporadic breast and ovarian cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

7 January 2021

A sporadic breast tumor with a somatically acquired complex genomic rearrangement in BRCA1

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

7 January 2021

Risks of cancer in BRCA1-mutation carriers. Breast Cancer Linkage Consortium

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

7 January 2021

Decreased expression of BRCA1 accelerates growth and is often present during sporadic breast cancer progression

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

7 January 2021

Decreased BRCA1 expression levels may arrest the cell cycle through activation of p53 checkpoint in human sporadic breast tumors

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

7 January 2021

Down-regulation of BRCA1 in human sporadic breast cancer; analysis of DNA methylation patterns of the putative promoter region

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

7 January 2021

Preferential allelic expression can lead to reduced expression of BRCA1 in sporadic breast cancers.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

7 January 2021

Frequent loss of BRCA1 mRNA and protein expression in sporadic ovarian cancers

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

7 January 2021

Identification of a C/G polymorphism in the promoter region of the BRCA1 gene and its use as a marker for rapid detection of promoter deletions

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

7 January 2021

Localization of human BRCA1 and its loss in high-grade, non-inherited breast carcinomas

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

7 January 2021

The Brn-3b POU family transcription factor represses expression of the BRCA-1 anti-oncogene in breast cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

7 January 2021

Regulation of BRCA1 by protein degradation

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

7 January 2021

CpG-rich islands and the function of DNA methylation

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

7 January 2021

A fraction of the mouse genome that is derived from islands of nonmethylated, CpG-rich DNA

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

7 January 2021

The essentials of DNA methylation

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

7 January 2021

Sp1 binding is inhibited by (m)Cp(m)CpG methylation.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

7 January 2021

Methylation-sensitive sequence-specific DNA binding by the c-Myc basic region

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

7 January 2021

Binding of AP-1/CREB proteins and of MDBP to contiguous sites downstream of the human TGF-beta 1 gene

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

7 January 2021

Effect of site-specific DNA methylation and mutagenesis on recognition by methylated DNA-binding protein from human placenta

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

7 January 2021

How does DNA methylation repress transcription?

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https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

7 January 2021

Gene silencing. Methylation meets acetylation.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

7 January 2021

Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

7 January 2021

DNA methylation, chromatin inheritance, and cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

7 January 2021

Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

7 January 2021

Silencing of the VHL tumor-suppressor gene by DNA methylation in renal carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

7 January 2021

Hypermethylation of the APC (adenomatous polyposis coli) gene promoter region in human colorectal carcinoma.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

7 January 2021

Cancer epigenetics comes of age

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

7 January 2021

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

1 reference

7 January 2021

DNA methylation in breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

7 January 2021

Distinct transcription start sites generate two forms of BRCA1 mRNA.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

7 January 2021

Complex regulation of the BRCA1 gene.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

7 January 2021

Positive regulation of the BRCA1 promoter

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

7 January 2021

Transcription of BRCA1 is dependent on the formation of a specific protein-DNA complex on the minimal BRCA1 Bi-directional promoter

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

7 January 2021

Promoter hypermethylation and BRCA1 inactivation in sporadic breast and ovarian tumors

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

7 January 2021

Tumour-specific distribution of BRCA1 promoter region methylation supports a pathogenetic role in breast and ovarian cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

7 January 2021

Methylation of the BRCA1 promoter is associated with decreased BRCA1 mRNA levels in clinical breast cancer specimens

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

7 January 2021

BRCA1 expression status in relation to DNA methylation of the BRCA1 promoter region in sporadic breast cancers.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

7 January 2021

CpG methylation within the 5' regulatory region of the BRCA1 gene is tumor specific and includes a putative CREB binding site

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

7 January 2021

Aberrant methylation of the BRCA1 CpG island promoter is associated with decreased BRCA1 mRNA in sporadic breast cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

7 January 2021

Transcriptional repression of BRCA1 by aberrant cytosine methylation, histone hypoacetylation and chromatin condensation of the BRCA1 promoter

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

7 January 2021

Regional methylation of the 5' end CpG island of BRCA1 is associated with reduced gene expression in human somatic cells

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

7 January 2021

Functional analysis of CpG methylation in the BRCA1 promoter region

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

7 January 2021

A CREB site in the BRCA1 proximal promoter acts as a constitutive transcriptional element

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

7 January 2021

Methylation of the BRCA1 promoter region in sporadic breast and ovarian cancer: correlation with disease characteristics

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

7 January 2021

DNA methylation patterns in hereditary human cancers mimic sporadic tumorigenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

7 January 2021

Gene-Expression Profiles in Hereditary Breast Cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

7 January 2021

Gene-expression profiles in hereditary breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

7 January 2021

Molecular portraits of human breast tumours

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

7 January 2021

Human DNA-(Cytosine-5) Methyltransferase-PCNA Complex as a Target for p21WAF1

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

7 January 2021

Aberrant CpG-island methylation has non-random and tumour-type-specific patterns.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

7 January 2021

Detection of breast cancer cells in ductal lavage fluid by methylation-specific PCR

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

7 January 2021

BRCA1 and BRCA2 and the genetics of breast and ovarian cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

7 January 2021

The role of DNA hypermethylation in human neoplasia

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

7 January 2021

DNA methylation, heterochromatin and epigenetic carcinogens

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

7 January 2021

Aberrant patterns of DNA methylation, chromatin formation and gene expression in cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

7 January 2021

Mutant BRCA1 genes antagonize phenotype of wild-type BRCA1

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900056-1

7 January 2021

10.1016/S1044-579X(02)00056-1

Identifiers

DOI

1 reference

4 August 2017

1 reference

PubMed ID

12191635