Re-emergence of interferon-α in the treatment of chronic myeloid leukemia (Q36989407)

17 August 2017

2 references

3 April 2019

20 November 2019

Re-emergence of interferon-α in the treatment of chronic myeloid leukemia (English)

1 reference

17 August 2017

chronic myeloid leukemia

2 references

3 April 2019

20 November 2019

1 reference

20 November 2019

1 reference

M Talpaz

1

1 reference

17 August 2017

R Hehlmann

2

1 reference

17 August 2017

A Quintás-Cardama

3

1 reference

17 August 2017

J Mercer

4

1 reference

17 August 2017

J Cortes

5

1 reference

17 August 2017

language of work or name

1 reference

7 November 2012

1 reference

17 August 2017

1 April 2013

2 references

3 April 2019

20 November 2019

3 references

17 August 2017

3 April 2019

20 November 2019

27

1 reference

17 August 2017

803-812

1 reference

17 August 2017

4

1 reference

Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

17 August 2017

2 references

3 April 2019

on focus list of Wikimedia project

20 November 2019

ScienceSource

0 references

exact match

https://scigraph.springernature.com/pub.10.1038/leu.2012.313

0 references

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Immune modulation of minimal residual disease in early chronic phase chronic myelogenous leukemia: a randomized trial of frontline high-dose imatinib mesylate with or without pegylated interferon alpha-2b and granulocyte-macrophage colony-stimulatin

29 September 2017

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Long-term prognostic significance of early molecular response to imatinib in newly diagnosed chronic myeloid leukemia: an analysis from the International Randomized Study of Interferon and STI571 (IRIS)

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29 September 2017

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High rates of durable response are achieved with imatinib after treatment with interferon alpha plus cytarabine: results from the International Randomized Study of Interferon and STI571 (IRIS) trial

29 September 2017

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Effects of imatinib and interferon on primitive chronic myeloid leukaemia progenitors

29 September 2017

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The development of imatinib as a therapeutic agent for chronic myeloid leukemia

29 September 2017

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Imatinib mesylate therapy improves survival in patients with newly diagnosed Philadelphia chromosome-positive chronic myelogenous leukemia in the chronic phase: comparison with historic data

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29 September 2017

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29 September 2017

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The p38 MAPK pathway mediates the growth inhibitory effects of interferon-alpha in BCR-ABL-expressing cells

29 September 2017

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29 September 2017

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Identification of genes differentially regulated by interferon alpha, beta, or gamma using oligonucleotide arrays

29 September 2017

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29 September 2017

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Type I interferon induction of the Cdk-inhibitor p21WAF1 is accompanied by ordered G1 arrest, differentiation and apoptosis of the Daudi B-cell line

29 September 2017

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29 September 2017

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Targeted T-cell therapy for human leukemia: cytotoxic T lymphocytes specific for a peptide derived from proteinase 3 preferentially lyse human myeloid leukemia cells

29 September 2017

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Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells

29 September 2017

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Treatment of myelogenous leukemia: current status and investigational options

29 September 2017

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Chronic myelogenous leukemia: a concise update

29 September 2017

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Persistence of dormant leukemic progenitors during interferon-induced remission in chronic myelogenous leukemia. Analysis by polymerase chain reaction of individual colonies

29 September 2017

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Interferon-alpha therapy for chronic myelogenous leukemia

29 September 2017

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Letter: A new consistent chromosomal abnormality in chronic myelogenous leukaemia identified by quinacrine fluorescence and Giemsa staining

29 September 2017

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Chronic myelogenous leukemia: a multivariate analysis of the associations of patient characteristics and therapy with survival

29 September 2017

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Diagnosis of chronic myeloid and acute lymphocytic leukemias by detection of leukemia-specific mRNA sequences amplified in vitro

29 September 2017

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Interferon alpha-2b as therapy for patients with Ph'-positive chronic myelogenous leukemia

29 September 2017

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Interferon alpha induces the expression of retinoblastoma gene product in human Burkitt lymphoma Daudi cells: role in growth regulation

29 September 2017

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Human chronic myeloid leukemia stem cells are insensitive to imatinib despite inhibition of BCR-ABL activity

29 September 2017

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Influence of interferon-alpha on cytokine expression by the bone marrow microenvironment--impact on treatment of myeloproliferative disorders

29 September 2017

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UK Medical Research Council randomised, multicentre trial of interferon-alpha n1 for chronic myeloid leukaemia: improved survival irrespective of cytogenetic response. The UK Medical Research Council's Working Parties for Therapeutic Trials in Adult

29 September 2017

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Long-term persistence of molecular response after discontinuation of interferon-alpha in two patients with chronic myeloid leukaemia

29 September 2017

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Discontinuation of imatinib in patients with chronic myeloid leukaemia who have maintained complete molecular remission for at least 2 years: the prospective, multicentre Stop Imatinib (STIM) trial

27 June 2018

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Hematologic and cytogenetic responses to imatinib mesylate in chronic myelogenous leukemia

27 June 2018

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The effect of interferon-alpha on beta-1 integrin mediated adhesion and growth regulation in chronic myelogenous leukemia

27 June 2018

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Clinical investigation of human alpha interferon in chronic myelogenous leukemia.

27 June 2018

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Induction of chronic myelogenous leukemia in mice by the P210bcr/abl gene of the Philadelphia chromosome

27 June 2018

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Acute leukaemia in bcr/abl transgenic mice

27 June 2018

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Early molecular and cytogenetic response is predictive for long-term progression-free and overall survival in chronic myeloid leukemia (CML).

27 June 2018

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Assessment of BCR-ABL1 transcript levels at 3 months is the only requirement for predicting outcome for patients with chronic myeloid leukemia treated with tyrosine kinase inhibitors.

4 September 2018

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Impact of additional cytogenetic aberrations at diagnosis on prognosis of CML: long-term observation of 1151 patients from the randomized CML Study IV.

4 September 2018

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Predicting complete cytogenetic response and subsequent progression-free survival in 2060 patients with CML on imatinib treatment: the EUTOS score

4 September 2018

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Tolerability-adapted imatinib 800 mg/d versus 400 mg/d versus 400 mg/d plus interferon-α in newly diagnosed chronic myeloid leukemia.

4 September 2018

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Patients with chronic myeloid leukemia who maintain a complete molecular response after stopping imatinib treatment have evidence of persistent leukemia by DNA PCR.

4 September 2018

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Dasatinib versus imatinib in newly diagnosed chronic-phase chronic myeloid leukemia

4 September 2018

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Sustained molecular response with interferon alfa maintenance after induction therapy with imatinib plus interferon alfa in patients with chronic myeloid leukemia

4 September 2018

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IFNalpha activates dormant haematopoietic stem cells in vivo.

4 September 2018

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Front-line treatment of Philadelphia positive chronic myeloid leukemia with imatinib and interferon-alpha: 5-year outcome

4 September 2018

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Imatinib mesylate discontinuation in patients with chronic myelogenous leukemia in complete molecular remission for more than 2 years.

4 September 2018

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Dasatinib (BMS-354825) targets an earlier progenitor population than imatinib in primary CML but does not eliminate the quiescent fraction

4 September 2018

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Phase I evaluation of a 40-kDa branched-chain long-acting pegylated IFN-alpha-2a with and without cytarabine in patients with chronic myelogenous leukemia

4 September 2018

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Discontinuation of imatinib therapy after achieving a molecular response

4 September 2018

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Imatinib and pegylated human recombinant interferon-alpha2b in early chronic-phase chronic myeloid leukemia

4 September 2018

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Pegylated recombinant interferon alpha-2b vs recombinant interferon alpha-2b for the initial treatment of chronic-phase chronic myelogenous leukemia: a phase III study.

4 September 2018

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Frequency of major molecular responses to imatinib or interferon alfa plus cytarabine in newly diagnosed chronic myeloid leukemia

4 September 2018

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Randomized comparison of interferon alpha and hydroxyurea with hydroxyurea monotherapy in chronic myeloid leukemia (CML-study II): prolongation of survival by the combination of interferon alpha and hydroxyurea

4 September 2018

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Persistence of malignant hematopoietic progenitors in chronic myelogenous leukemia patients in complete cytogenetic remission following imatinib mesylate treatment

4 September 2018

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Complete cytogenetic and molecular responses to interferon-alpha-based therapy for chronic myelogenous leukemia are associated with excellent long-term prognosis

4 September 2018

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Interferon-alpha, but not the ABL-kinase inhibitor imatinib (STI571), induces expression of myeloblastin and a specific T-cell response in chronic myeloid leukemia

4 September 2018

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Interferon-alpha induces dendritic cell differentiation of CML mononuclear cells in vitro and in vivo.

4 September 2018

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A randomized study of interferon-alpha versus interferon-alpha and low-dose arabinosyl cytosine in chronic myeloid leukemia

4 September 2018

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Follow-up of complete cytogenetic remission in patients with chronic myeloid leukemia after cessation of interferon alfa

4 September 2018

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Primitive, quiescent, Philadelphia-positive stem cells from patients with chronic myeloid leukemia are insensitive to STI571 in vitro

4 September 2018

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Phase 1 study of polyethylene glycol formulation of interferon alpha-2B (Schering 54031) in Philadelphia chromosome-positive chronic myelogenous leukemia.

4 September 2018

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GM-CSF can improve the cytogenetic response obtained with interferon-alpha therapy in patients with chronic myelogenous leukemia.

4 September 2018

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Long-term treatment of chronic myelogenous leukemia with different interferons: results from three studies.

4 September 2018

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4 September 2018

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Intensive chemotherapy induction followed by interferon-alpha maintenance in patients with Philadelphia chromosome-positive chronic myelogenous leukemia

4 September 2018

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21 January 2018

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Survival advantage from imatinib compared with the combination interferon- plus cytarabine in chronic-phase chronic myelogenous leukemia: historical comparison between two phase 3 trials

20 October 2018

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A cellular oncogene is translocated to the Philadelphia chromosome in chronic myelocytic leukaemia

21 January 2018

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Crossref

https://api.crossref.org/works/10.1038%2FLEU.2012.313

Imatinib mesylate therapy in chronic myeloid leukemia patients in stable complete cytogenic response after interferon-alpha results in a very high complete molecular response rate

21 January 2018

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12 December 2020

Phase II, randomized, multicenter, comparative study of peginterferon-alpha-2a (40 kD) (Pegasys) versus interferon alpha-2a (Roferon-A) in patients with treatment-naïve, chronic-phase chronic myelogenous leukemia

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12 December 2020

Detection of two alternative bcr/abl mRNA junctions and minimal residual disease in Philadelphia chromosome positive chronic myelogenous leukemia by polymerase chain reaction

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12 December 2020

Molecular heterogeneity in complete cytogenetic responders after interferon-alpha therapy for chronic myelogenous leukemia: low levels of minimal residual disease are associated with continuing remission. German CML Study Group and the UK MRC CML St

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12 December 2020

Treatment of Philadelphia chromosome-positive early chronic phase chronic myelogenous leukemia with daily doses of interferon alpha and low-dose cytarabine

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12 December 2020

Involvement of Fas-mediated apoptosis in the inhibitory effects of interferon-alpha in chronic myelogenous leukemia

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12 December 2020

Dasatinib combined with interferon-alfa induces a complete cytogenetic response and major molecular response in a patient with chronic myelogenous leukemia harboring the T315I BCR-ABL1 mutation

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12 December 2020

NCCN clinical practice guidelines in oncology: chronic myelogenous leukemia

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12 December 2020

Immune-mediated and unusual complications during interferon alfa therapy in chronic myelogenous leukemia

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12 December 2020

Detection of minimal residual bcr/abl transcripts by a modified polymerase chain reaction

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12 December 2020

Response at three months is a good predictive factor for newly diagnosed chronic myeloid leukemia patients treated by recombinant interferon-alpha

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12 December 2020

Effect of recombinant alpha-interferon on the expression of the bcr-abl fusion gene in human chronic myelogenous human leukemia cell lines

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12 December 2020

Detection of minimal residual disease by polymerase chain reaction in Philadelphia chromosome-positive chronic myelogenous leukemia following interferon therapy

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12 December 2020

Treatment of advanced stages of Philadelphia chromosome-positive chronic myelogenous leukemia with interferon-alpha and low-dose cytarabine

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12 December 2020

Combined interferon alfa-2a and cytosine arabinoside as first-line treatment for chronic myeloid leukemia

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12 December 2020

Leukocyte interferon-induced myeloid cytoreduction in chronic myelogenous leukemia

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12 December 2020

Interferon-alpha produces sustained cytogenetic responses in chronic myelogenous leukemia. Philadelphia chromosome-positive patients

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12 December 2020

Interferon alfa-2b combined with cytarabine versus interferon alone in chronic myelogenous leukemia. French Chronic Myeloid Leukemia Study Group

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12 December 2020

Evidence that specific T lymphocytes may participate in the elimination of chronic myelogenous leukemia

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12 December 2020

Interferon alfa-2a as compared with conventional chemotherapy for the treatment of chronic myeloid leukemia

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12 December 2020

Survival benefit with imatinib mesylate versus interferon-alpha-based regimens in newly diagnosed chronic-phase chronic myelogenous leukemia

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12 December 2020

Prolonged subcutaneous administration of recombinant alpha 2b interferon in patients with previously untreated Philadelphia chromosome-positive chronic-phase chronic myelogenous leukemia: effect on remission duration and survival: Cancer and Leukemi

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12 December 2020

Successful treatment of a chronic-phase T-315I-mutated chronic myelogenous leukemia patient with a combination of imatinib and interferon-alfa

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12 December 2020

Treatment with interferon alpha prior to discontinuation of imatinib in patients with chronic myeloid leukemia

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12 December 2020

The minute chromosome (Phl) in chronic granulocytic leukemia

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12 December 2020

Interferon alfa versus chemotherapy for chronic myeloid leukemia: a meta-analysis of seven randomized trials: Chronic Myeloid Leukemia Trialists' Collaborative Group

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12 December 2020

Efficacy and safety of imatinib in patients with chronic myeloid leukemia and complete or near-complete cytogenetic response to interferon-alpha

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12 December 2020

A randomized trial comparing interferon-alpha with busulfan for newly diagnosed chronic myelogenous leukemia in chronic phase

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12 December 2020

Identifiers

DOI

10.1038/LEU.2012.313

1 reference

17 August 2017

1 reference

17 August 2017

1 reference