Decoding dangerous death: how cytotoxic chemotherapy invokes inflammation, immunity or nothing at all. (Q37002810)

17 August 2017

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title

Decoding dangerous death: how cytotoxic chemotherapy invokes inflammation, immunity or nothing at all. (English)

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17 August 2017

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van der Most RG

1

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17 August 2017

Currie AJ

series ordinal

2

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17 August 2017

Robinson BW

series ordinal

3

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17 August 2017

Lake RA

series ordinal

4

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17 August 2017

16 November 2007

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Cell Death & Differentiation

17 August 2017

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17 August 2017

15

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17 August 2017

1

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17 August 2017

13-20

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https://scigraph.springernature.com/pub.10.1038/sj.cdd.4402255

17 August 2017

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21 January 2018

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The chemotherapeutic agent DMXAA potently and specifically activates the TBK1-IRF-3 signaling axis

21 January 2018

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ROS-dependent activation of the TRAF6-ASK1-p38 pathway is selectively required for TLR4-mediated innate immunity.

21 January 2018

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Toll-like receptor 3 promotes cross-priming to virus-infected cells.

21 January 2018

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Signaling of apoptosis through TLRs critically involves toll/IL-1 receptor domain-containing adapter inducing IFN-beta, but not MyD88, in bacteria-infected murine macrophages

21 January 2018

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TLR3 can directly trigger apoptosis in human cancer cells.

21 January 2018

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Toll-like receptors on tumor cells facilitate evasion of immune surveillance

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Listeria monocytogenes promotes tumor growth via tumor cell toll-like receptor 2 signaling

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Addicted to death: invasive cancer and the immune response to unscheduled cell death

21 January 2018

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Toll-like receptor-independent gene induction program activated by mammalian DNA escaped from apoptotic DNA degradation

21 January 2018

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A Toll-like receptor-independent antiviral response induced by double-stranded B-form DNA.

21 January 2018

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Double-stranded DNA and double-stranded RNA induce a common antiviral signaling pathway in human cells

21 January 2018

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Recognition of cytosolic DNA activates an IRF3-dependent innate immune response

21 January 2018

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RAX, the PKR activator, sensitizes cells to inflammatory cytokines, serum withdrawal, chemotherapy, and viral infection

21 January 2018

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21 January 2018

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Cytolytic cells induce HMGB1 release from melanoma cell lines

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High mobility group box 1 protein interacts with multiple Toll-like receptors

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Toll-like receptor 4-dependent contribution of the immune system to anticancer chemotherapy and radiotherapy

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Toll-like receptor 9-dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE

21 January 2018

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Intracellular and extracellular functions of heat shock proteins: repercussions in cancer therapy.

21 January 2018

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Peptides chaperoned by heat-shock proteins are a necessary and sufficient source of antigen in the cross-priming of CD8+ T cells

21 January 2018

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Heat shock proteins: biological functions and clinical application as personalized vaccines for human cancer.

21 January 2018

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Molecular identification of a danger signal that alerts the immune system to dying cells

21 January 2018

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Cutting edge: elimination of an endogenous adjuvant reduces the activation of CD8 T lymphocytes to transplanted cells and in an autoimmune diabetes model

21 January 2018

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Uric acid promotes tumor immune rejection

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21 January 2018

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The inflammasome: first line of the immune response to cell stress

21 January 2018

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Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3

21 January 2018

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Gout-associated uric acid crystals activate the NALP3 inflammasome

21 January 2018

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Inflammatory caspases and inflammasomes: master switches of inflammation

21 January 2018

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MyD88-dependent IL-1 receptor signaling is essential for gouty inflammation stimulated by monosodium urate crystals

21 January 2018

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Engagement of CD14 mediates the inflammatory potential of monosodium urate crystals.

21 January 2018

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Uric acid stimulates monocyte chemoattractant protein-1 production in vascular smooth muscle cells via mitogen-activated protein kinase and cyclooxygenase-2.

21 January 2018

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Role of peroxide and superoxide anion during tumour cell apoptosis

21 January 2018

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Melphalan-induced expression of IFN-beta in MOPC-315 tumor-bearing mice and its importance for the up-regulation of TNF-alpha expression

21 January 2018

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Mechanism of melphalan-induced B7-1 gene expression in P815 tumor cells

21 January 2018

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The NEMO adaptor bridges the nuclear factor-kappaB and interferon regulatory factor signaling pathways

21 January 2018

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Hypochlorous acid enhances immunogenicity and uptake of allogeneic ovarian tumor cells by dendritic cells to cross-prime tumor-specific T cells.

21 January 2018

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Chemoresistance of endothelial cells induced by basic fibroblast growth factor depends on Raf-1-mediated inhibition of the proapoptotic kinase, ASK1.

21 January 2018

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Metronomic cyclophosphamide regimen selectively depletes CD4+CD25+ regulatory T cells and restores T and NK effector functions in end stage cancer patients

21 January 2018

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Importance of signaling via the IFN-alpha/beta receptor on host cells for the realization of the therapeutic benefits of cyclophosphamide for mice bearing a large MOPC-315 tumor.

21 January 2018

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The DNA damage pathway regulates innate immune system ligands of the NKG2D receptor

21 January 2018

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The DNA damage response arouses the immune system

21 January 2018

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IFN-dependent down-regulation of the NKG2D ligand H60 on tumors

21 January 2018

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Systemic NKG2D down-regulation impairs NK and CD8 T cell responses in vivo

21 January 2018

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Altered NKG2D function in NK cells induced by chronic exposure to NKG2D ligand-expressing tumor cells

21 January 2018

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Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas

21 January 2018

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Induction of tumor cell apoptosis in vivo increases tumor antigen cross-presentation, cross-priming rather than cross-tolerizing host tumor-specific CD8 T cells

21 January 2018

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Cell-associated double-stranded RNA enhances antitumor activity through the production of type I IFN.

21 January 2018

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Identification of a key pathway required for the sterile inflammatory response triggered by dying cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402255

Paradoxical roles of the immune system during cancer development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402255

Inhibition of inducible nitric oxide synthase enhances anti-tumour immune responses in rats immunized with IFN-gamma-secreting glioma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402255

Cyclophosphamide induces the development of early myeloid cells suppressing tumor cell growth by a nitric oxide-dependent mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402255

IL-17 family cytokines and the expanding diversity of effector T cell lineages

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402255

IL-23 promotes tumour incidence and growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402255

Systemic administration of IL-23 induces potent antitumor immunity primarily mediated through Th1-type response in association with the endogenously expressed IL-12.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402255

Inflammatory mediators are insufficient for full dendritic cell activation and promote expansion of CD4+ T cell populations lacking helper function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402255

Immunotherapy and chemotherapy--a practical partnership

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402255

7 January 2021

Another detour on the Toll road to the interferon antiviral response

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402255

7 January 2021

The inflammatory tumor microenvironment and its impact on cancer development

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402255

7 January 2021

Low-Level Monocyte Chemoattractant Protein-1 Stimulation of Monocytes Leads to Tumor Formation in Nontumorigenic Melanoma Cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402255

7 January 2021

Identifiers

DOI

10.1038/SJ.CDD.4402255

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17 August 2017

1 reference