Methods for meta-analysis in genetic association studies: a review of their potential and pitfalls (Q37008455)

17 August 2017

1 reference

title

Methods for meta-analysis in genetic association studies: a review of their potential and pitfalls (English)

1 reference

17 August 2017

0 references

2

John P A Ioannidis

0 references

author name string

Fotini K Kavvoura

series ordinal

1

1 reference

17 August 2017

publication date

17 November 2007

1 reference

17 August 2017

1 reference

17 August 2017

volume

123

1 reference

17 August 2017

issue

1

1 reference

17 August 2017

page(s)

1-14

1 reference

Sample bias among women with retained DNA samples for future genetic studies

17 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1007%2FS00439-007-0445-9

5,10-Methylenetetrahydrofolate reductase gene variants and congenital anomalies: a HuGE review

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00439-007-0445-9

N-acetyltransferase polymorphisms and colorectal cancer: a HuGE review

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00439-007-0445-9

Homocysteine and stroke: evidence on a causal link from mendelian randomisation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00439-007-0445-9

Outcome reporting bias in randomized trials funded by the Canadian Institutes of Health Research

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00439-007-0445-9

Glutathione S-transferase polymorphisms and colorectal cancer: a HuGE review

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00439-007-0445-9

Bias in meta-analysis detected by a simple, graphical test

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00439-007-0445-9

The appropriateness of asymmetry tests for publication bias in meta-analyses: a large survey

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00439-007-0445-9

Effects of CCR5-Delta32, CCR2-64I, and SDF-1 3'A alleles on HIV-1 disease progression: An international meta-analysis of individual-patient data.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00439-007-0445-9

Reporting, appraising, and integrating data on genotype prevalence and gene-disease associations

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00439-007-0445-9

Random-effects meta-analyses are not always conservative.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00439-007-0445-9

The association between common vitamin D receptor gene variations and osteoporosis: a participant-level meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00439-007-0445-9

Welcome to the genomic era.

21 January 2018

1 reference

12 December 2020

Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels

1 reference

12 December 2020

Comparison of DNA- and RNA-based methods for detection of truncating BRCA1 mutations

1 reference

12 December 2020

Genome-wide association studies for common diseases and complex traits

1 reference

12 December 2020

Uncertainty in heterogeneity estimates in meta-analyses

1 reference

12 December 2020

Gene-environment interactions in human diseases

1 reference

12 December 2020

Identifying outcome reporting bias in randomised trials on PubMed: review of publications and survey of authors

1 reference

12 December 2020

Relative citation impact of various study designs in the health sciences

1 reference

12 December 2020

Meta-analysis in genome-wide association datasets: strategies and application in Parkinson disease

1 reference

12 December 2020

Principal components analysis corrects for stratification in genome-wide association studies

1 reference

12 December 2020

Quantifying heterogeneity in a meta-analysis

1 reference

12 December 2020

A Bayesian measure of the probability of false discovery in genetic epidemiology studies

1 reference

12 December 2020

Detecting and describing heterogeneity in meta-analysis

1 reference

12 December 2020

How vague is vague? A simulation study of the impact of the use of vague prior distributions in MCMC using WinBUGS.

1 reference

12 December 2020

Counterpoint: bias from population stratification is not a major threat to the validity of conclusions from epidemiological studies of common polymorphisms and cancer.

1 reference

12 December 2020

The case of the misleading funnel plot

1 reference

12 December 2020

Data trawling: to fish or not to fish

1 reference

12 December 2020

Meta-analyses of molecular association studies: methodologic lessons for genetic epidemiology

1 reference

12 December 2020

Clinical epidemiological quality in molecular genetic research: the need for methodological standards

1 reference

12 December 2020

New models of collaboration in genome-wide association studies: the Genetic Association Information Network

1 reference

12 December 2020

Case-control association tests correcting for population stratification

1 reference

12 December 2020

Genome-wide association study identifies novel breast cancer susceptibility loci

1 reference

12 December 2020

The Human Genome Epidemiology Network

1 reference

12 December 2020

Invited commentary: a critical look at some popular meta-analytic methods

1 reference

12 December 2020

Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes

1 reference

12 December 2020

Operating characteristics of a rank correlation test for publication bias

1 reference

12 December 2020

Large-scale evidence for the effect of the COLIA1 Sp1 polymorphism on osteoporosis outcomes: the GENOMOS study

1 reference

12 December 2020

Sifting the evidence-what's wrong with significance tests?

1 reference

12 December 2020

Joint effect of genes and environment distorted by selection biases: implications for hospital-based case-control studies.

1 reference

12 December 2020

A modified test for small-study effects in meta-analyses of controlled trials with binary endpoints

1 reference

12 December 2020

In an empirical evaluation of the funnel plot, researchers could not visually identify publication bias.

1 reference

12 December 2020

Estimation of magnitude in gene-environment interactions in the presence of measurement error.

1 reference

12 December 2020

Empirical evidence for selective reporting of outcomes in randomized trials: comparison of protocols to published articles

1 reference

12 December 2020

The publication process itself was the major cause of publication bias in genetic epidemiology

1 reference

12 December 2020

Bayesian meta-analysis and meta-regression for gene-disease associations and deviations from Hardy-Weinberg equilibrium.

1 reference

12 December 2020

Association mapping in structured populations

1 reference

12 December 2020

Make it HuGE: human genome epidemiology reviews, population health, and the IJE

1 reference

12 December 2020

A comprehensive review of genetic association studies

1 reference

12 December 2020

Misleading funnel plot for detection of bias in meta-analysis

1 reference

12 December 2020

Meta-analysis in clinical trials

1 reference

12 December 2020

Design and analysis of admixture mapping studies

1 reference

12 December 2020

The path from genome-based research to population health: development of an international public health genomics network

1 reference

12 December 2020

A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity

1 reference

12 December 2020

Assessing the probability that a positive report is false: an approach for molecular epidemiology studies

1 reference

12 December 2020

Selective reporting biases in cancer prognostic factor studies

1 reference

12 December 2020

Why most published research findings are false

1 reference

12 December 2020

Mendelian randomisation: a new spin or real progress?

1 reference

12 December 2020

Trim and fill: A simple funnel-plot-based method of testing and adjusting for publication bias in meta-analysis

1 reference

12 December 2020

Commentary: meta-analysis of individual participants' data in genetic epidemiology

1 reference

12 December 2020

The Emergence of Networks in Human Genome Epidemiology

1 reference

12 December 2020

The hazards of scoring the quality of clinical trials for meta-analysis

1 reference

12 December 2020

How should meta-regression analyses be undertaken and interpreted?

1 reference

12 December 2020

Heterogeneity in meta-analyses of genome-wide association investigations

1 reference

12 December 2020

Commentary: grading the credibility of molecular evidence for complex diseases

1 reference

12 December 2020

Accounting for unmeasured population substructure in case-control studies of genetic association using a novel latent-class model

1 reference

12 December 2020

Misclassification of genetic susceptibility biomarkers: implications for case-control studies and cross-population comparisons.

1 reference

12 December 2020

Genotyping errors: causes, consequences and solutions

1 reference

12 December 2020

Local literature bias in genetic epidemiology: an empirical evaluation of the Chinese literature

1 reference

12 December 2020

Selection in reported epidemiological risks: an empirical assessment

1 reference

12 December 2020

Assessing heterogeneity in meta-analysis: Q statistic or I2 index?

1 reference

12 December 2020

An exploratory test for an excess of significant findings

1 reference

12 December 2020

Meta-analysis of Observational Studies in Epidemiology: A Proposal for Reporting

1 reference

12 December 2020

Measuring inconsistency in meta-analyses

1 reference

12 December 2020

1 reference

12 December 2020

Joint analysis is more efficient than replication-based analysis for two-stage genome-wide association studies

1 reference

12 December 2020

Population stratification and spurious allelic association

1 reference

12 December 2020

The Breast Cancer Family Registry: an infrastructure for cooperative multinational, interdisciplinary and translational studies of the genetic epidemiology of breast cancer

1 reference

12 December 2020

A candidate gene approach to searching for low-penetrance breast and prostate cancer genes

1 reference

12 December 2020

Sources of evidence for systematic reviews of interventions in diabetes

1 reference

12 December 2020

Comparison of two methods to detect publication bias in meta-analysis

1 reference

12 December 2020

Meta-analysis of the literature or of individual patient data: is there a difference?

1 reference

12 December 2020

Factors influencing publication of research results. Follow-up of applications submitted to two institutional review boards

1 reference

12 December 2020

Statistical heterogeneity in systematic reviews of clinical trials: a critical appraisal of guidelines and practice.

1 reference

12 December 2020

Recent developments in genomewide association scans: a workshop summary and review

1 reference

12 December 2020

A network of investigator networks in human genome epidemiology

1 reference

12 December 2020

Genetic effects on HIV disease progression

1 reference

12 December 2020

Meta-analysis of genetic studies in ischemic stroke: thirty-two genes involving approximately 18,000 cases and 58,000 controls.

1 reference

12 December 2020

A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants

1 reference

12 December 2020

Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database

1 reference

12 December 2020

Genetic effects versus bias for candidate polymorphisms in myocardial infarction: case study and overview of large-scale evidence

1 reference

12 December 2020

Non-replication and inconsistency in the genome-wide association setting

1 reference

12 December 2020

Establishment of genetic associations for complex diseases is independent of early study findings

1 reference

12 December 2020

The merits of testing Hardy-Weinberg equilibrium in the analysis of unmatched case-control data: a cautionary note

1 reference

12 December 2020

Does apolipoprotein E genotype influence the risk of ischemic stroke, intracerebral hemorrhage, or subarachnoid hemorrhage? Systematic review and meta-analyses of 31 studies among 5961 cases and 17,965 controls.

1 reference

12 December 2020

Selection bias in the assessment of gene-environment interaction in case-control studies.

1 reference

12 December 2020

A road map for efficient and reliable human genome epidemiology

1 reference

12 December 2020

Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease

1 reference

12 December 2020

Statistical aspects of the analysis of data from retrospective studies of disease

1 reference

12 December 2020

Language bias in randomised controlled trials published in English and German.

1 reference

12 December 2020

Journals should publish all "null" results and should sparingly publish "positive" results.

1 reference

12 December 2020

Replication validity of genetic association studies

1 reference

12 December 2020

Assessing publication bias in genetic association studies: evidence from a recent meta-analysis.

1 reference

12 December 2020

Family-based versus unrelated case-control designs for genetic associations

1 reference

12 December 2020

Are vitamin D receptor polymorphisms associated with bone mineral density? A meta-analysis

1 reference

12 December 2020

Publication bias in clinical research

1 reference

12 December 2020

To IPD or not to IPD? Advantages and disadvantages of systematic reviews using individual patient data

1 reference

12 December 2020

Replicating genotype-phenotype associations

1 reference

12 December 2020

Early extreme contradictory estimates may appear in published research: the Proteus phenomenon in molecular genetics research and randomized trials

1 reference

12 December 2020

Flexible design for following up positive findings

1 reference

12 December 2020

Effect of the statistical significance of results on the time to completion and publication of randomized efficacy trials

1 reference

12 December 2020

Tracking the epidemiology of human genes in the literature: the HuGE Published Literature database

1 reference

12 December 2020

An empirical evaluation of multifarious outcomes in pharmacogenetics: beta-2 adrenoceptor gene polymorphisms in asthma treatment

1 reference

12 December 2020

Cumulative meta-analysis of clinical trials builds evidence for exemplary medical care.

1 reference

12 December 2020

Genetics of ischaemic stroke among persons of non-European descent: a meta-analysis of eight genes involving approximately 32,500 individuals

1 reference

12 December 2020

CTLA-4 gene polymorphisms and susceptibility to type 1 diabetes mellitus: a HuGE Review and meta-analysis

1 reference

12 December 2020

Beta blockade during and after myocardial infarction: an overview of the randomized trials

1 reference

12 December 2020

Genetic variation and willingness to participate in epidemiologic research: data from three studies

1 reference

12 December 2020

Population stratification in epidemiologic studies of common genetic variants and cancer: quantification of bias

1 reference

12 December 2020

Turning the Pump Handle: Evolving Methods for Integrating the Evidence on Gene-Disease Association

1 reference

12 December 2020

Genomic control, a new approach to genetic-based association studies

1 reference

12 December 2020

Association of gene polymorphism with genetic susceptibility to stroke in Asian populations: a meta-analysis

1 reference

12 December 2020

Common genetic variants for breast cancer: 32 largely refuted candidates and larger prospects

1 reference

12 December 2020

Molecular evidence-based medicine: evolution and integration of information in the genomic era.

1 reference

12 December 2020

Association of collagen Ialpha 1 Sp1 polymorphism with the risk of prevalent fractures: a meta-analysis.

1 reference

12 December 2020

Summing up evidence: one answer is not always enough.

1 reference

12 December 2020

‘Mendelian randomization’: can genetic epidemiology contribute to understanding environmental determinants of disease?*

1 reference

12 December 2020

10.1007/S00439-007-0445-9

Identifiers

DOI

1 reference

17 August 2017

1 reference