dsRNA binding properties of RDE-4 and TRBP reflect their distinct roles in RNAi (Q37020940)

17 August 2017

dsRNA binding properties of RDE-4 and TRBP reflect their distinct roles in RNAi (English)

1 reference

17 August 2017

Greg S Parker

1

1 reference

17 August 2017

Tuhin Subhra Maity

series ordinal

2

1 reference

17 August 2017

Brenda L Bass

series ordinal

3

1 reference

17 August 2017

language of work or name

English

0 references

publication date

11 October 2008

1 reference

Journal of Molecular Biology

17 August 2017

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17 August 2017

384

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17 August 2017

967-979

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17 August 2017

4

1 reference

describes a project that uses

17 August 2017

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2605707/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

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Two molecular features contribute to the Argonaute specificity for the microRNA and RNAi pathways in C. elegans

29 September 2017

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Role of Dicer in posttranscriptional RNA silencing

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Drosophila microRNAs are sorted into functionally distinct argonaute complexes after production by dicer-1.

29 September 2017

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Genes misregulated in C. elegans deficient in Dicer, RDE-4, or RDE-1 are enriched for innate immunity genes

29 September 2017

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Human TRBP and PACT directly interact with each other and associate with dicer to facilitate the production of small interfering RNA

29 September 2017

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Dicer-2 and R2D2 coordinately bind siRNA to promote assembly of the siRISC complexes

29 September 2017

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RDE-4 preferentially binds long dsRNA and its dimerization is necessary for cleavage of dsRNA to siRNA.

29 September 2017

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29 September 2017

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A human, ATP-independent, RISC assembly machine fueled by pre-miRNA

29 September 2017

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TRBP, a regulator of cellular PKR and HIV-1 virus expression, interacts with Dicer and functions in RNA silencing

29 September 2017

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TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing

29 September 2017

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Oligomerization activity of a double-stranded RNA-binding domain

29 September 2017

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R2D2, a Bridge Between the Initiation and Effector Steps of the Drosophila RNAi Pathway

29 September 2017

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The dsRNA binding protein family: critical roles, diverse cellular functions

29 September 2017

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Human Dicer preferentially cleaves dsRNAs at their termini without a requirement for ATP

29 September 2017

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Ribonuclease activity and RNA binding of recombinant human Dicer

29 September 2017

1 reference

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The dsRNA binding protein RDE-4 interacts with RDE-1, DCR-1, and a DExH-box helicase to direct RNAi in C. elegans

29 September 2017

1 reference

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Distinct roles for RDE-1 and RDE-4 during RNA interference in Caenorhabditis elegans

29 September 2017

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Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans

29 September 2017

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A role for the RNase III enzyme DCR-1 in RNA interference and germ line development in Caenorhabditis elegans

29 September 2017

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A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA

29 September 2017

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Two dimerization domains in the trans-activation response RNA-binding protein (TRBP) individually reverse the protein kinase R inhibition of HIV-1 long terminal repeat expression

29 September 2017

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Modular structure of PACT: distinct domains for binding and activating PKR

29 September 2017

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Analysis of a binding difference between the two dsRNA-binding domains in TRBP reveals the modular function of a KR-helix motif

29 September 2017

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The rde-1 gene, RNA interference, and transposon silencing in C. elegans

29 September 2017

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PACT, a protein activator of the interferon-induced protein kinase, PKR.

29 September 2017

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29 September 2017

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Double-stranded-RNA-dependent protein kinase and TAR RNA-binding protein form homo- and heterodimers in vivo

29 September 2017

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On the thermodynamics and kinetics of the cooperative binding of bacteriophage T4-coded gene 32 (helix destabilizing) protein to nucleic acid lattices

29 September 2017

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DNA "melting" proteins. IV. Fluorescence measurements of binding parameters for bacteriophage T4 gene 32-protein to mono-, oligo-, and polynucleotides

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Cooperative and noncooperative binding of protein ligands to nucleic acid lattices: experimental approaches to the determination of thermodynamic parameters.

27 June 2018

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Interactions between the double-stranded RNA-binding proteins TRBP and PACT define the Medipal domain that mediates protein-protein interactions

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605707

A differential cytolocalization assay for analysis of macromolecular assemblies in the eukaryotic cytoplasm

4 September 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605707

A Dicer-2-dependent 80s complex cleaves targeted mRNAs during RNAi in Drosophila

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605707

The carboxy-terminal, M3 motifs of PACT and TRBP have opposite effects on PKR activity

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605707

Structural features of small RNA precursors determine Argonaute loading in Caenorhabditis elegans

4 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18948111

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.JMB.2008.10.002

1 reference

17 August 2017

1 reference

17 August 2017

1 reference