The role of PACT in the RNA silencing pathway (Q24301564)

Protein activator of interferon induced protein kinase EIF2AK2

1 reference

Argonaute RISC catalytic component 2

1 reference

pre-miRNA processing

1 reference

6

V Narry Kim

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author name string

Yoontae Lee

1

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Inha Hur

2

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Seong-Yeon Park

3

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Young-Kook Kim

4

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Mi Ra Suh

A human, ATP-independent, RISC assembly machine fueled by pre-miRNA

5

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language of work or name

English

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publication date

8 February 2006

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published in

The EMBO Journal

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volume

25

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issue

3

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page(s)

522-32

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cites work

1 reference

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TRBP, a regulator of cellular PKR and HIV-1 virus expression, interacts with Dicer and functions in RNA silencing

19 March 2017

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TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing

19 March 2017

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Normal microRNA maturation and germ-line stem cell maintenance requires Loquacious, a double-stranded RNA-binding domain protein

19 March 2017

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Processing of pre-microRNAs by the Dicer-1-Loquacious complex in Drosophila cells

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The Drosha-DGCR8 complex in primary microRNA processing

19 March 2017

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The Microprocessor complex mediates the genesis of microRNAs

19 March 2017

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Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAs

19 March 2017

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MicroRNA genes are transcribed by RNA polymerase II

19 March 2017

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Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs

19 March 2017

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Exportin 5 is a RanGTP-dependent dsRNA-binding protein that mediates nuclear export of pre-miRNAs

19 March 2017

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Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs

19 March 2017

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The nuclear RNase III Drosha initiates microRNA processing

19 March 2017

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Short-interfering-RNA-mediated gene silencing in mammalian cells requires Dicer and eIF2C translation initiation factors

19 March 2017

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MicroRNA maturation: stepwise processing and subcellular localization

19 March 2017

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Modular structure of PACT: distinct domains for binding and activating PKR

19 March 2017

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The B56alpha regulatory subunit of protein phosphatase 2A is a target for regulation by double-stranded RNA-dependent protein kinase PKR

19 March 2017

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PACT, a protein activator of the interferon-induced protein kinase, PKR.

19 March 2017

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The crystal structure of the Argonaute2 PAZ domain reveals an RNA binding motif in RNAi effector complexes

19 March 2017

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Structure and conserved RNA binding of the PAZ domain

19 March 2017

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Processing of primary microRNAs by the Microprocessor complex

19 March 2017

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Argonaute2 is the catalytic engine of mammalian RNAi

19 March 2017

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MicroRNAs: genomics, biogenesis, mechanism, and function

19 March 2017

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Nuclear export of microRNA precursors

19 March 2017

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Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing

19 March 2017

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A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA

19 March 2017

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Role for a bidentate ribonuclease in the initiation step of RNA interference

19 March 2017

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Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans

19 March 2017

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Human RISC couples microRNA biogenesis and posttranscriptional gene silencing

19 March 2017

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Purified Argonaute2 and an siRNA form recombinant human RISC

7 April 2017

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The human DiGeorge syndrome critical region gene 8 and Its D. melanogaster homolog are required for miRNA biogenesis

19 March 2017

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Structural basis for overhang-specific small interfering RNA recognition by the PAZ domain

19 March 2017

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Dicer is essential for mouse development

19 March 2017

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The Argonaute family: tentacles that reach into RNAi, developmental control, stem cell maintenance, and tumorigenesis

19 March 2017

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Characterization of two evolutionarily conserved, alternatively spliced nuclear phosphoproteins, NFAR-1 and -2, that function in mRNA processing and interact with the double-stranded RNA-dependent protein kinase, PKR

19 March 2017

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A double-stranded RNA binding protein required for activation of repressed messages in mammalian germ cells

19 March 2017

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MicroRNA biogenesis: coordinated cropping and dicing

19 March 2017

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Ribo-gnome: the big world of small RNAs

7 April 2017

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Perspective: machines for RNAi

7 April 2017

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Crystal structure of Argonaute and its implications for RISC slicer activity

7 April 2017

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Distinct roles for Drosophila Dicer-1 and Dicer-2 in the siRNA/miRNA silencing pathways

7 April 2017

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R2D2, a Bridge Between the Initiation and Effector Steps of the Drosophila RNAi Pathway

7 April 2017

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Argonaute2, a link between genetic and biochemical analyses of RNAi

7 April 2017

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PKR and eIF2alpha: integration of kinase dimerization, activation, and substrate docking

7 April 2017

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Crystal structure of A. aeolicus argonaute, a site-specific DNA-guided endoribonuclease, provides insights into RISC-mediated mRNA cleavage

27 September 2017

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RNAi: the nuts and bolts of the RISC machine

27 September 2017

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Dicer-1 and R3D1-L catalyze microRNA maturation in Drosophila

27 September 2017

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Structural basis for 5'-end-specific recognition of guide RNA by the A. fulgidus Piwi protein

27 September 2017

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27 September 2017

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Assembly and function of RNA silencing complexes

27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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RISC assembly defects in the Drosophila RNAi mutant armitage.

27 September 2017

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27 September 2017

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Molecular requirements for RNA-induced silencing complex assembly in the Drosophila RNA interference pathway.

30 May 2018

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A Dicer-2-dependent 80s complex cleaves targeted mRNAs during RNAi in Drosophila

29 November 2018

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The carboxy-terminal, M3 motifs of PACT and TRBP have opposite effects on PKR activity

29 November 2018

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Regulation of apoptosis by alternative pre-mRNA splicing

29 November 2018

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Crossref

https://api.crossref.org/works/10.1038%2FSJ.EMBOJ.7600942

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/SJ.EMBOJ.7600942

1 reference

1 reference

1 reference

PubMed publication ID

16424907

1 reference