MPTP mechanisms of neurotoxicity and their implications for Parkinson's disease (Q37045190)

17 August 2017

1 reference

title

MPTP mechanisms of neurotoxicity and their implications for Parkinson's disease (English)

1 reference

17 August 2017

1 reference

1 reference

1 reference

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1815982

1 December 2022

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

1 December 2022

author name string

M. Gerlach

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1815982

1 December 2022

P. Riederer

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1815982

1 December 2022

H. Przuntek

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1815982

1 December 2022

M. B. Youdim

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1815982

1 December 2022

language of work or name

English

0 references

publication date

1 December 1991

1 reference

17 August 2017

12 December 1991

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=1815982

full work available at URL

1 December 2022

https://api.elsevier.com/content/article/PII:092241069190073Q?httpAccept=text/xml

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

https://api.elsevier.com/content/article/PII:092241069190073Q?httpAccept=text/plain

1 December 2022

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

European Journal of Pharmacology

1 December 2022

published in

1 reference

17 August 2017

208

1 reference

17 August 2017

4

1 reference

17 August 2017

273-286

1 reference

Induction by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine of lipid peroxidation in vivo in vitamin E deficient mice.

17 August 2017

1

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Enhancement by tetraphenylboron of inhibition of mitochondrial respiration induced by 1-methyl-4-phenylpyridinium ion (MPP(+))

1 December 2022

2

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Evaluation of a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated C57 black mouse model for parkinsonism

1 December 2022

3

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Structure-neurotoxicity trends of analogues of 1-methyl-4-phenylpyridinium (MPP+), the cytotoxic metabolite of the dopaminergic neurotoxin MPTP

1 December 2022

4

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

The iron chelator desferrioxamine (Desferal) retards 6-hydroxydopamine-induced degeneration of nigrostriatal dopamine neurons.

1 December 2022

5

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

A primate model of parkinsonism: selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

1 December 2022

8

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Chemically induced Parkinson's disease: intermediates in the oxidation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine to the 1-methyl-4-phenyl-pyridinium ion

1 December 2022

9

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Metabolism of the neurotoxic tertiary amine, MPTP, by brain monoamine oxidase.

1 December 2022

10

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Active uptake of MPP+, a metabolite of MPTP, by brain synaptosomes.

1 December 2022

12

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) neurotoxicity in mice is enhanced by pretreatment with diethyldithiocarbamate.

1 December 2022

14

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Selectivity of the parkinsonian neurotoxin MPTP: toxic metabolite MPP+ binds to neuromelanin.

1 December 2022

15

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Long-term effect of MPTP in the mouse brain in relation to aging: neurochemical and immunocytochemical analysis.

1 December 2022

16

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Chronic parkinsonism secondary to intravenous injection of meperidine analogues

1 December 2022

17

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

A dopaminergic cell line variant resistant to the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.

1 December 2022

18

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and 1-methyl-4-phenylpyridine (MPP+) cause rapid ATP depletion in isolated hepatocytes

1 December 2022

19

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Role of 1-methyl-4-phenylpyridinium ion formation and accumulation in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity to isolated hepatocytes

1 December 2022

20

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Fructose prevents 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced ATP depletion and toxicity in isolated hepatocytes

1 December 2022

21

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Diethyldithiocarbamate and disulfiram inhibit MPP+ and dopamine uptake by striatal synaptosomes

1 December 2022

22

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Variability and functional recovery in the N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of parkinsonism in monkeys.

1 December 2022

23

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Symptomatic and asymptomatic 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated primates: biochemical changes in striatal regions

1 December 2022

25

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Locus ceruleus lesions and eosinophilic inclusions in MPTP-treated monkeys.

1 December 2022

28

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

An electron microscopic study of MPTP-induced inclusion bodies in an old monkey

1 December 2022

29

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

N-methyl-4-phenylpyridine (MMP+) together with 6-hydroxydopamine or dopamine stimulates Ca2+ release from mitochondria

1 December 2022

30

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Metabolism of the neurotoxin in MPTP by human liver monoamine oxidase B.

1 December 2022

31

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Tissue concentrations of MPTP and MPP+ in relation to catecholamine depletion after the oral or subcutaneous administration of MPTP to mice

1 December 2022

33

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonian syndrome in Macaca fascicularis: which midbrain dopaminergic neurons are lost?

1 December 2022

34

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Aged mice are more sensitive to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine treatment than young adults.

1 December 2022

35

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) accelerates the accumulation of lipofuscin in mouse adrenal gland

1 December 2022

36

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

1-Methyl-4-phenylpyridinium (MPP+) induces NADH-dependent superoxide formation and enhances NADH-dependent lipid peroxidation in bovine heart submitochondrial particles

1 December 2022

37

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Protection against the dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine by monoamine oxidase inhibitors

1 December 2022

38

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Dopaminergic toxicity after the stereotaxic administration of the 1-methyl-4-phenylpyridinium ion (MPP+) to rats.

1 December 2022

39

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Dopaminergic toxicity of rotenone and the 1-methyl-4-phenylpyridinium ion after their stereotaxic administration to rats: implication for the mechanism of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity.

1 December 2022

40

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Some features of the nigrostriatal dopaminergic neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in the mouse

1 December 2022

41

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Inhibition of mitochondrial respiration by analogs of 4-phenylpyridine and 1-methyl-4-phenylpyridinium cation (MPP+), the neurotoxic metabolite of MPTP

1 December 2022

42

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Selective accumulation of MPP+ in the substantia nigra: a key to neurotoxicity?

1 December 2022

43

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

The evolution of nigrostriatal neurochemical changes in the MPTP-treated squirrel monkey.

1 December 2022

44

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Uptake of MPP(+) by dopamine neurons explains selectivity of parkinsonism-inducing neurotoxin, MPTP.

1 December 2022

45

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonism in the common marmoset.

1 December 2022

48

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Differences in the metabolism of MPTP in the rodent and primate parallel differences in sensitivity to its neurotoxic effects.

1 December 2022

50

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Blood-brain barrier monoamine oxidase: enzyme characterization in cerebral microvessels and other tissues from six mammalian species, including human.

1 December 2022

51

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

The mechanism of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity: role of intracellular calcium

1 December 2022

52

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

The neurotoxicity of 1-methyl-4-phenyl-1,2,3,6,-tetrahydropyridine (mptp) and its relevance to parkinson's disease

1 December 2022

53

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Demonstration of monoamine oxidase-A and -B in the human brainstem by a histochemical technique

1 December 2022

54

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Evidence for the one-electron oxidation of 1-methyl-4-phenyl-2,3-dihydropyridinium (MPDP+).

1 December 2022

56

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Oxygen activation during the interaction between MPTP metabolites and synthetic neuromelanin--an ESR-spin trapping, optical, and oxidase electrode study

1 December 2022

57

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Evidence that the blockade of mitochondrial respiration by the neurotoxin 1-methyl-4-phenylpyridinium (MPP+) involves binding at the same site as the respiratory inhibitor, rotenone

1 December 2022

58

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

MPTP-induced ATP depletion and cell death in neuroblastoma X glioma hybrid NG 108-15 cells: protection by glucose and sensitization by tetraphenylborate

1 December 2022

59

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis

1 December 2022

61

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Selective nigral toxicity after systemic administration of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyrine (MPTP) in the squirrel monkey

1 December 2022

62

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Pargyline Prevents MPTP-Induced Parkinsonism in Primates

1 December 2022

63

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Normal mitochondrial genome in brain from patients with Parkinson's disease and complex I defect

1 December 2022

64

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Intraneuronal generation of a pyridinium metabolite may cause drug-induced parkinsonism.

1 December 2022

66

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Evaluation of the toxicity of the dopaminergic neurotoxins MPTP and MPP+ in PC12 pheochromocytoma cells: binding and biological studies

1 December 2022

67

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Systemic administration of antioxidants does not protect mice against the dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine (MPTP).

1 December 2022

68

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Dopamine but not norepinephrine or serotonin uptake inhibitors protect mice against neurotoxicity of MPTP.

1 December 2022

69

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Immunity of fetal mice to prenatal administration of the dopaminergic neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.

1 December 2022

70

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Toxicity of 1-methyl-4-phenylpyridinium for rat dopaminergic neurons in culture: selectivity and irreversibility

1 December 2022

71

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Treatment with antioxidants does not prevent loss of dopamine in the striatum of MPTP-treated common marmosets: preliminary observations

1 December 2022

72

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Sites of the neurotoxic action of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in the macaque monkey include the ventral tegmental area and the locus coeruleus.

1 December 2022

73

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and 1-methyl-4-phenylpyridinium ion on activities of the enzymes in the electron transport system in mouse brain

1 December 2022

74

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Deprenyl protects dopamine neurons from the neurotoxic effect of 1-methyl-4-phenylpyridinium ion.

1 December 2022

75

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

1-Methyl-4-phenylpyridine (MPP+) is toxic to mesencephalic dopamine neurons in culture

1 December 2022

76

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Histochemistry of MPTP oxidation in the rat brain: sites of synthesis of the parkinsonism-inducing toxin MPP+.

1 December 2022

77

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Inhibition of aromatic L-aminoacid decarboxylase in clonal pheochromocytoma PC12h cells by N-methyl-4-phenylpyridinium ion (MPP+).

1 December 2022

78

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Inhibition of NADH-linked oxidation in brain mitochondria by 1-methyl-4-phenyl-pyridine, a metabolite of the neurotoxin, 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine.

1 December 2022

79

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Inactivation of tyrosine hydroxylase in rat striatum by 1-methyl-4-phenylpyridinium ion (MPP+).

1 December 2022

80

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Evidence for a defect in NADH: ubiquinone oxidoreductase (complex I) in Huntington's disease

1 December 2022

81

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Partial protection from the dopaminergic neurotoxin N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine by four different antioxidants in the mouse.

1 December 2022

82

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Extrastriatal dopamine in symptomatic and asymptomatic rhesus monkeys treated with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).

1 December 2022

83

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

The specific vulnerability of the substantia nigra to MPTP is related to the presence of transition metals

1 December 2022

84

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

The protective effect of 1-tert.butyl-4,4-diphenylpiperidine against the nigrostriatal neurodegeneration caused by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

1 December 2022

85

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Energy-driven uptake of N-methyl-4-phenylpyridine by brain mitochondria mediates the neurotoxicity of MPTP.

1 December 2022

86

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Inhibition of mitochondrial NADH dehydrogenase by pyridine derivatives and its possible relation to experimental and idiopathic parkinsonism

1 December 2022

87

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

The inhibition site of MPP+, the neurotoxic bioactivation product of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine is near the Q-binding site of NADH dehydrogenase

1 December 2022

88

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Inhibition of NADH oxidation by pyridine derivatives

1 December 2022

89

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Evidence that the inhibition sites of the neurotoxic amine 1-methyl-4-phenylpyridinium (MPP+) and of the respiratory chain inhibitor piericidin A are the same

1 December 2022

90

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Astrocytes convert the parkinsonism inducing neurotoxin, MPTP, to its active metabolite, MPP+

1 December 2022

91

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Strain differences in systemic 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity in mice correlate best with monoamine oxidase activity at the blood-brain barrier

1 December 2022

93

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Fate of nigrostriatal neurons in young mature mice given 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine: a neurochemical and morphological reassessment.

1 December 2022

94

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

MPTP induced dopaminergic neurotoxicity-a useful model in the study of parkinson's disease?

1 December 2022

95

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Changes in lipid peroxidation induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and 1-methyl-4-phenylpyridinium in mouse brain homogenates

1 December 2022

97

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

The role of striatopallidal neurones utilizing gamma-aminobutyric acid in the pathophysiology of MPTP-induced parkinsonism in the primate: evidence from [3H]flunitrazepam autoradiography

1 December 2022

98

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

1-Methyl-4-(2'-methylphenyl)-1,2,3,6-tetrahydropyridine (2'-methyl-MPTP) is less neurotoxic than MPTP in the common marmoset

1 December 2022

99

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Neurochemical and behavioural features induced by chronic low dose treatment with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in the common marmoset: implications for Parkinson's disease?

1 December 2022

100

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Oxidation of the neurotoxic amine 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) by monoamine oxidases A and B and suicide inactivation of the enzymes by MPTP

1 December 2022

101

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Biochemical mechanism of action of the dopaminergic neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).

1 December 2022

102

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Tetraphenylborate potentiates the respiratory inhibition by the dopaminergic neurotoxin MPP+ in both electron transport particles and intact mitochondria

1 December 2022

103

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Mitochondrial complex I deficiency in Parkinson's disease

1 December 2022

104

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Production of a Parkinson-like syndrome in the cat with N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP): behavior, histology, and biochemistry.

1 December 2022

105

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and 1-methyl-4-phenylpyridinium ion on ATP levels of mouse brain synaptosomes.

1 December 2022

106

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Dose-dependent destruction of the coeruleus-cortical and nigral-striatal projections by MPTP.

1 December 2022

107

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Protection against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity by the antioxidant ascorbic acid.

1 December 2022

108

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Serotonergic conversion of MPTP and dopaminergic accumulation of MPP+.

1 December 2022

109

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Cation-exchange high-performance liquid chromatography assay for the nigrostriatal toxicant 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and its monoamine oxidase B generated metabolites in brain tissues

1 December 2022

110

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Calcium in the brain under physiological and pathological conditions

1 December 2022

111

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Reversible inhibition and mechanism-based irreversible inactivation of monoamine oxidases by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).

1 December 2022

112

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Interactions of the neurotoxic amine 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine with monoamine oxidases

1 December 2022

113

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Biochemical events in the development of parkinsonism induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

1 December 2022

114

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

The influence of dose and dosing interval on MPTP-induced dopaminergic neurotoxicity in mice.

1 December 2022

115

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Role for excitatory amino acids in methamphetamine-induced nigrostriatal dopaminergic toxicity.

1 December 2022

116

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Monoamine oxidase, brain ageing and degenerative diseases

1 December 2022

117

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Neurotoxic damage to the nigrostriatal system in rats following intranigral administration of MPDP+ and MPP+

1 December 2022

118

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Chronic neurochemical and behavioral changes in MPTP-lesioned C57BL/6 mice: a model for Parkinson's disease.

1 December 2022

119

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Astroglial ablation prevents MPTP-induced nigrostriatal neuronal death.

1 December 2022

120

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Oxidation and enzyme-activated irreversible inhibition of rat liver monoamine oxidase-B by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).

1 December 2022

121

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Protection of substantia nigra from MPP+ neurotoxicity by N-methyl-D-aspartate antagonists

1 December 2022

122

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Further treatment with MPTP does not produce parkinsonism in marmosets showing behavioural recovery from motor deficits induced by an earlier exposure to the toxin

1 December 2022

123

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Studies on the neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine: inhibition of NAD-linked substrate oxidation by its metabolite, 1-methyl-4-phenylpyridinium.

1 December 2022

124

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Ascorbic acid reduces the dopamine depletion induced by MPTP.

1 December 2022

125

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

An immunohistochemical study of the acute and long-term effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in the marmoset

1 December 2022

126

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Dissociation between biochemical and behavioral recovery in MPTP-treated mice

1 December 2022

127

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Distinct monoamine oxidase A and B populations in primate brain.

1 December 2022

128

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Interactions of the 1-methyl-4-phenyl-2,3-dihydropyridinium species with synthetic dopamine-melanin

1 December 2022

129

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

Depletion of glutathione in brainstem of mice caused by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine is prevented by antioxidant pretreatment.

1 December 2022

130

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

1-Methyl-4-cyclohexyl-1,2,3,6-tetrahydropyridine (MCTP): an alicyclic MPTP-like neurotoxin

1 December 2022

133

1 reference

https://api.crossref.org/works/10.1016/0922-4106(91)90073-Q

1 December 2022

Identifiers

1 reference

17 August 2017

1 reference