Human immunodeficiency virus type 2 (HIV-2)/HIV-1 envelope chimeras detect high titers of broadly reactive HIV-1 V3-specific antibodies in human plasma (Q37051645)

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English	Human immunodeficiency virus type 2 (HIV-2)/HIV-1 envelope chimeras detect high titers of broadly reactive HIV-1 V3-specific antibodies in human plasma	scientific article

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Europe PubMed Central

PMC publication ID

17 August 2017

Human immunodeficiency virus type 2 (HIV-2)/HIV-1 envelope chimeras detect high titers of broadly reactive HIV-1 V3-specific antibodies in human plasma (English)

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Europe PubMed Central

PMC publication ID

17 August 2017

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Frederic Bibollet-Ruche

2

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Frederic Bibollet-Ruche

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Beatrice H. Hahn

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Beatrice H Hahn

10

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5

object named as

Olaf Kutsch

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Europe PubMed Central

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17 August 2017

6

object named as

Lynn Morris

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17 August 2017

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12

object named as

George M Shaw

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Europe PubMed Central

17 August 2017

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11

object named as

Peter D Kwong

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Europe PubMed Central

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17 August 2017

9

object named as

James A Hoxie

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Europe PubMed Central

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17 August 2017

author name string

Katie L Davis

1

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17 August 2017

Hui Li

3

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17 August 2017

Julie M Decker

4

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Europe PubMed Central

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17 August 2017

Aidy Salomon

7

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Europe PubMed Central

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17 August 2017

Abraham Pinter

8

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17 August 2017

language of work or name

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publication date

19 November 2008

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17 August 2017

Journal of Virology

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Europe PubMed Central

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17 August 2017

83

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Europe PubMed Central

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17 August 2017

3

1 reference

Europe PubMed Central

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17 August 2017

1240-1259

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Europe PubMed Central

PMC publication ID

17 August 2017

Analysis of neutralization specificities in polyclonal sera derived from human immunodeficiency virus type 1-infected individuals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2620909

29 September 2017

B cell recognition of the conserved HIV-1 co-receptor binding site is altered by endogenous primate CD4.

1 reference

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29 September 2017

Neutralizing activity of antibodies to the V3 loop region of HIV-1 gp120 relative to their epitope fine specificity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2620909

29 September 2017

Profiling the specificity of neutralizing antibodies in a large panel of plasmas from patients chronically infected with human immunodeficiency virus type 1 subtypes B and C.

1 reference

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29 September 2017

Soluble CD4 broadens neutralization of V3-directed monoclonal antibodies and guinea pig vaccine sera against HIV-1 subtype B and C reference viruses

1 reference

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29 September 2017

Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection

1 reference

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29 September 2017

Selection of T1249-resistant human immunodeficiency virus type 1 variants

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29 September 2017

Deciphering human immunodeficiency virus type 1 transmission and early envelope diversification by single-genome amplification and sequencing

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The challenges of eliciting neutralizing antibodies to HIV-1 and to influenza virus.

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4E10-resistant variants in a human immunodeficiency virus type 1 subtype C-infected individual with an anti-membrane-proximal external region-neutralizing antibody response

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29 September 2017

Structure of Antibody F425-B4e8 in Complex with a V3 Peptide Reveals a New Binding Mode for HIV-1 Neutralization

1 reference

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29 September 2017

The c3-v4 region is a major target of autologous neutralizing antibodies in human immunodeficiency virus type 1 subtype C infection

1 reference

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29 September 2017

Roles of HIV-1 Env variable regions in viral neutralization and vaccine development

1 reference

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29 September 2017

Subtype-specific conformational differences within the V3 region of subtype B and subtype C human immunodeficiency virus type 1 Env proteins

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29 September 2017

Structures of the CCR5 N Terminus and of a Tyrosine-Sulfated Antibody with HIV-1 gp120 and CD4

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29 September 2017

V3 loop truncations in HIV-1 envelope impart resistance to coreceptor inhibitors and enhanced sensitivity to neutralizing antibodies

1 reference

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Broad HIV-1 neutralization mediated by CD4-binding site antibodies

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29 September 2017

Analysis of the neutralization breadth of the anti-V3 antibody F425-B4e8 and re-assessment of its epitope fine specificity by scanning mutagenesis

1 reference

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Neutralizing antibody responses in acute human immunodeficiency virus type 1 subtype C infection

1 reference

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Dissecting the neutralizing antibody specificities of broadly neutralizing sera from human immunodeficiency virus type 1-infected donors

1 reference

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29 September 2017

Unique mutational patterns in the envelope alpha 2 amphipathic helix and acquisition of length in gp120 hypervariable domains are associated with resistance to autologous neutralization of subtype C human immunodeficiency virus type 1.

1 reference

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29 September 2017

Structural definition of a conserved neutralization epitope on HIV-1 gp120

1 reference

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Type-specific epitopes targeted by monoclonal antibodies with exceptionally potent neutralizing activities for selected strains of human immunodeficiency virus type 1 map to a common region of the V2 domain of gp120 and differ only at single positio

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29 September 2017

Role of V1V2 and other human immunodeficiency virus type 1 envelope domains in resistance to autologous neutralization during clade C infection

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The HIV Env variant N283 enhances macrophage tropism and is associated with brain infection and dementia.

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Human immunodeficiency virus type 1 V1-V2 envelope loop sequences expand and add glycosylation sites over the course of infection, and these modifications affect antibody neutralization sensitivity

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Factors determining the breadth and potency of neutralization by V3-specific human monoclonal antibodies derived from subjects infected with clade A or clade B strains of human immunodeficiency virus type 1

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29 September 2017

Cross-clade neutralizing activity of human anti-V3 monoclonal antibodies derived from the cells of individuals infected with non-B clades of human immunodeficiency virus type 1.

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29 September 2017

Improving on nature: focusing the immune response on the V3 loop.

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29 September 2017

Evidence for potent autologous neutralizing antibody titers and compact envelopes in early infection with subtype C human immunodeficiency virus type 1

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29 September 2017

GP120: target for neutralizing HIV-1 antibodies

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29 September 2017

Simian immunodeficiency virus engrafted with human immunodeficiency virus type 1 (HIV-1)-specific epitopes: replication, neutralization, and survey of HIV-1-positive plasma

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Neutralizing antibody responses drive the evolution of human immunodeficiency virus type 1 envelope during recent HIV infection

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29 September 2017

Structure of a V3-containing HIV-1 gp120 core

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Human immunodeficiency virus type 1 env clones from acute and early subtype B infections for standardized assessments of vaccine-elicited neutralizing antibodies

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Cryptic nature of a conserved, CD4-inducible V3 loop neutralization epitope in the native envelope glycoprotein oligomer of CCR5-restricted, but not CXCR4-using, primary human immunodeficiency virus type 1 strains

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Antigenic conservation and immunogenicity of the HIV coreceptor binding site

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Cardiolipin polyspecific autoreactivity in two broadly neutralizing HIV-1 antibodies.

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Structure of an unliganded simian immunodeficiency virus gp120 core

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29 September 2017

V3: HIV's switch-hitter

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Antibodies that are cross-reactive for human immunodeficiency virus type 1 clade a and clade B v3 domains are common in patient sera from Cameroon, but their neutralization activity is usually restricted by epitope masking

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Determinants of human immunodeficiency virus type 1 escape from the primary CD8+ cytotoxic T lymphocyte response

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Structure and mechanistic analysis of the anti-human immunodeficiency virus type 1 antibody 2F5 in complex with its gp41 epitope

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The V1/V2 domain of gp120 is a global regulator of the sensitivity of primary human immunodeficiency virus type 1 isolates to neutralization by antibodies commonly induced upon infection

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Structural rationale for the broad neutralization of HIV-1 by human monoclonal antibody 447-52D

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Access of antibody molecules to the conserved coreceptor binding site on glycoprotein gp120 is sterically restricted on primary human immunodeficiency virus type 1

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Antibody neutralization and escape by HIV-1

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Rapid evolution of the neutralizing antibody response to HIV type 1 infection

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Human monoclonal antibodies specific for conformation-sensitive epitopes of V3 neutralize human immunodeficiency virus type 1 primary isolates from various clades.

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Emergence of resistant human immunodeficiency virus type 1 in patients receiving fusion inhibitor (T-20) monotherapy.

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A variable region 3 (V3) mutation determines a global neutralization phenotype and CD4-independent infectivity of a human immunodeficiency virus type 1 envelope associated with a broadly cross-reactive, primary virus-neutralizing antibody response

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Neutralizing antibodies associated with viremia control in a subset of individuals after treatment of acute human immunodeficiency virus type 1 infection

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29 September 2017

Relationships between CD4 independence, neutralization sensitivity, and exposure of a CD4-induced epitope in a human immunodeficiency virus type 1 envelope protein

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29 September 2017

Loss of a single N-linked glycan allows CD4-independent human immunodeficiency virus type 1 infection by altering the position of the gp120 V1/V2 variable loops

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Increased neutralization sensitivity of CD4-independent human immunodeficiency virus variants

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Use of inhibitors to evaluate coreceptor usage by simian and simian/human immunodeficiency viruses and human immunodeficiency virus type 2 in primary cells

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29 September 2017

The neutralizing antibody response to HIV-1: viral evasion and escape from humoral immunity

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29 September 2017

Specific interaction of CCR5 amino-terminal domain peptides containing sulfotyrosines with HIV-1 envelope glycoprotein gp120

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Sequential CD4-coreceptor interactions in human immunodeficiency virus type 1 Env function: soluble CD4 activates Env for coreceptor-dependent fusion and reveals blocking activities of antibodies against cryptic conserved epitopes on gp120.

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29 September 2017

Analysis of the critical domain in the V3 loop of human immunodeficiency virus type 1 gp120 involved in CCR5 utilization

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29 September 2017

Stable exposure of the coreceptor-binding site in a CD4-independent HIV-1 envelope protein

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29 September 2017

Neutralizing antibodies have limited effects on the control of established HIV-1 infection in vivo.

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29 September 2017

Determinants of human immunodeficiency virus type 1 envelope glycoprotein activation by soluble CD4 and monoclonal antibodies

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29 September 2017

The antigenic structure of the HIV gp120 envelope glycoprotein

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29 September 2017

A conserved HIV gp120 glycoprotein structure involved in chemokine receptor binding

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29 September 2017

The HIV-1 Envelope Glycoproteins: Fusogens, Antigens, and Immunogens

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29 September 2017

Human monoclonal antibodies to the V3 loop of HIV-1 with intra- and interclade cross-reactivity.

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29 September 2017

Autologous and heterologous neutralizing antibody responses following initial seroconversion in human immunodeficiency virus type 1-infected individuals.

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29 September 2017

Antiviral pressure exerted by HIV-1-specific cytotoxic T lymphocytes (CTLs) during primary infection demonstrated by rapid selection of CTL escape virus

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29 September 2017

Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome

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29 September 2017

Virus-specific CD8+ cytotoxic T-lymphocyte activity associated with control of viremia in primary human immunodeficiency virus type 1 infection

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29 September 2017

Cryptic nature of envelope V3 region epitopes protects primary monocytotropic human immunodeficiency virus type 1 from antibody neutralization

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29 September 2017

Characterization of neutralizing monoclonal antibodies to linear and conformation-dependent epitopes within the first and second variable domains of human immunodeficiency virus type 1 gp120

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29 September 2017

An infectious chimeric human immunodeficiency virus type 2 (HIV-2) expressing the HIV-1 principal neutralizing determinant

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29 September 2017

Presentation of native epitopes in the V1/V2 and V3 regions of human immunodeficiency virus type 1 gp120 by fusion glycoproteins containing isolated gp120 domains

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29 September 2017

Principal neutralizing domain of the human immunodeficiency virus type 1 envelope protein

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29 September 2017

Human immunodeficiency virus type 1 neutralization epitope with conserved architecture elicits early type-specific antibodies in experimentally infected chimpanzees

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2620909

29 September 2017

Antibodies that inhibit fusion of human immunodeficiency virus-infected cells bind a 24-amino acid sequence of the viral envelope, gp120

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2620909

29 September 2017

Type-specific neutralization of the human immunodeficiency virus with antibodies to env-encoded synthetic peptides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2620909

29 September 2017

Emergence of viruses resistant to neutralization by V3-specific antibodies in experimental human immunodeficiency virus type 1 IIIB infection of chimpanzees.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2620909

29 September 2017

Envelope cross-reactivity between human immunodeficiency virus types 1 and 2 detected by different serological methods: correlation between cross-neutralization and reactivity against the main neutralizing site.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2620909

29 September 2017

Production of site-selected neutralizing human monoclonal antibodies against the third variable domain of the human immunodeficiency virus type 1 envelope glycoprotein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2620909

29 September 2017

Identification of the envelope V3 loop as the primary determinant of cell tropism in HIV-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2620909

29 September 2017

Molecular characterization of human immunodeficiency virus type 1 cloned directly from uncultured human brain tissue: identification of replication-competent and -defective viral genomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2620909

29 September 2017

Neutralization of diverse human immunodeficiency virus type 1 variants by an anti-V3 human monoclonal antibody

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2620909

29 September 2017

Complete nucleotide sequence, genome organization, and biological properties of human immunodeficiency virus type 1 in vivo: evidence for limited defectiveness and complementation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2620909

29 September 2017

Envelope sequences of two new United States HIV-1 isolates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2620909

27 June 2018

HIV-2 antisera cross-neutralize HIV-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2620909

27 June 2018

Complete nucleotide sequences of functional clones of the AIDS virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2620909

27 June 2018

Interpretation and use of the western blot assay for serodiagnosis of human immunodeficiency virus type 1 infections

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2620909

27 June 2018

Rapid development of isolate-specific neutralizing antibodies after primary HIV-1 infection and consequent emergence of virus variants which resist neutralization by autologous sera.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2620909

27 June 2018

Epitopes recognized by the neutralizing antibodies of an HIV-1-infected individual

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2620909

27 June 2018

Structural basis of enhanced binding of extended and helically constrained peptide epitopes of the broadly neutralizing HIV-1 antibody 4E10.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2620909

4 September 2018

HIV vaccine design and the neutralizing antibody problem

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2620909

4 September 2018

Neutralizing antibody responses to human immunodeficiency virus type 1 in primary infection and long-term-nonprogressive infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2620909

4 September 2018

Fine definition of a conserved CCR5-binding region on the human immunodeficiency virus type 1 glycoprotein 120

1 reference

https://pubmed.ncbi.nlm.nih.gov/19019969

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Conformational changes in env oligomer induced by an antibody dependent on the V3 loop base

1 reference

https://pubmed.ncbi.nlm.nih.gov/19019969

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Focusing the immune response on the V3 loop, a neutralizing epitope of the HIV-1 gp120 envelope

1 reference

https://pubmed.ncbi.nlm.nih.gov/19019969

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Repertoire of neutralizing human monoclonal antibodies specific for the V3 domain of HIV-1 gp120

1 reference

https://pubmed.ncbi.nlm.nih.gov/19019969

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Principal neutralizing domain of HIV-1 is highly immunogenic when expressed on the surface of hepatitis B core particles

1 reference

https://pubmed.ncbi.nlm.nih.gov/19019969

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The cross-clade neutralizing activity of a human monoclonal antibody is determined by the GPGR V3 motif of HIV type 1

1 reference

https://pubmed.ncbi.nlm.nih.gov/19019969

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/JVI.01743-08

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

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