Rat Urinary Bladder Carcinogenesis by Dual-Acting PPARalpha + gamma Agonists (Q37077098)

18 August 2017

1 reference

title

Rat Urinary Bladder Carcinogenesis by Dual-Acting PPARalpha + gamma Agonists (English)

1 reference

18 August 2017

1 reference

Jennifer Southgate

2

0 references

author name string

Martin B Oleksiewicz

series ordinal

1

1 reference

PMCID

2632771

18 August 2017

Lars Iversen

series ordinal

3

1 reference

PMCID

2632771

18 August 2017

Frederikke L Egerod

series ordinal

4

1 reference

18 August 2017

1 January 2008

1 reference

18 August 2017

1 reference

18 August 2017

2008

1 reference

18 August 2017

103167

1 reference

Creative Commons Attribution 3.0 Unported

18 August 2017

start time

1 January 2008

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

1 reference

April 2022 Public Data File from Crossref

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Mechanisms of epithelial development and neoplasia in the metanephric kidney

29 September 2017

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29 September 2017

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29 September 2017

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Peroxisome proliferator-activated receptor gene expression in human tissues. Effects of obesity, weight loss, and regulation by insulin and glucocorticoids

29 September 2017

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Urea-inducible Egr-1 transcription in renal inner medullary collecting duct (mIMCD3) cells is mediated by extracellular signal-regulated kinase activation

29 September 2017

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The effects of dietary fatty acids on the proliferation of normal human urothelial cells in vitro.

29 September 2017

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Luteinizing hormone deficiency and female infertility in mice lacking the transcription factor NGFI-A (Egr-1)

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Promoting effect of the peroxisome proliferator, clofibrate, but not di(2-ethylhexyl)phthalate, on urinary bladder carcinogenesis in F344 rats initiated by N-butyl-N-(4-hydroxybutyl)nitrosamine

29 September 2017

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Synergistic vascular protective effects of combined low doses of PPARalpha and PPARgamma activators in angiotensin II-induced hypertension in rats

29 September 2017

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Spatial and isoform specific p63 expression in the male human urogenital tract

27 June 2018

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Gender differences in renal nuclear receptors and aryl hydrocarbon receptor in 5/6 nephrectomized rats

27 June 2018

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Intragranular pH rapidly modulates exocytosis in adrenal chromaffin cells

27 June 2018

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Akt promotes increased mammalian cell size by stimulating protein synthesis and inhibiting protein degradation

27 June 2018

1 reference

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Expression of peroxisome proliferator-activated receptors in urinary tract of rabbits and humans.

27 June 2018

1 reference

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Effects of pH on nonenzymatic oxidation of phenylhydroquinone: potential role in urinary bladder carcinogenesis induced by o-phenylphenol in Fischer 344 rats

27 June 2018

1 reference

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Normal human urothelial cells in vitro: proliferation and induction of stratification.

27 June 2018

1 reference

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Effects of a dietary load of acid or base on changes induced by lactose in rats

27 June 2018

1 reference

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The influence of pH on the vesicular traffic to the surface of the polarized epithelial cell, MDCK.

27 June 2018

1 reference

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Rosiglitazone, a PPAR gamma agonist: potent promoter of hydroxybutyl(butyl)nitrosamine-induced urinary bladder cancers

27 June 2018

1 reference

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Urothelial carcinogenesis in the urinary bladder of rats treated with naveglitazar, a gamma-dominant PPAR alpha/gamma agonist: lack of evidence for urolithiasis as an inciting event

4 September 2018

1 reference

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Trans-species comparison of PPAR and RXR expression by rat and human urothelial tissues.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2632771

PPAR-gamma ligand promotes the growth of APC-mutated HT-29 human colon cancer cells in vitro and in vivo

4 September 2018

1 reference

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Urine acidification has no effect on peroxisome proliferator-activated receptor (PPAR) signaling or epidermal growth factor (EGF) expression in rat urinary bladder urothelium.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2632771

Urinary tract diseases and bladder cancer risk: a case-control study.

4 September 2018

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Ameliorative effect of combination of fenofibrate and rosiglitazone in pressure overload-induced cardiac hypertrophy in rats.

4 September 2018

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Gender and genetic differences in bladder smooth muscle PPAR mRNA in a porcine model of the metabolic syndrome.

4 September 2018

1 reference

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Urothelial carcinogenesis in the urinary bladder of male rats treated with muraglitazar, a PPAR alpha/gamma agonist: Evidence for urolithiasis as the inciting event in the mode of action.

4 September 2018

1 reference

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Biomarkers for early effects of carcinogenic dual-acting PPAR agonists in rat urinary bladder urothelium in vivo

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2632771

Selling safety--lessons from muraglitazar

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2632771

The PROactive study: some answers, many questions

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2632771

Urothelial differentiation in chronically urine-deprived bladders of patients with end-stage renal disease

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2632771

Generalized cellular hypertrophy is induced by a dual-acting PPAR agonist in rat urinary bladder urothelium in vivo

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2632771

Attenuation of extracellular acidic pH-induced cyclooxygenase-2 expression by nitric oxide.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2632771

Autocrine regulation of human urothelial cell proliferation and migration during regenerative responses in vitro

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2632771

Peroxisome proliferator-activated receptor gamma-independent activation of p38 MAPK by thiazolidinediones involves calcium/calmodulin-dependent protein kinase II and protein kinase R: correlation with endoplasmic reticulum stress

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2632771

Troglitazone acts on cellular pH and DNA synthesis through a peroxisome proliferator-activated receptor gamma-independent mechanism in breast cancer-derived cell lines

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2632771

PPAR-gamma2 expression in response to cafeteria diet: gender- and depot-specific effects

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2632771

Identification of pretreatment agents to enhance adenovirus infection of bladder epithelium

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2632771

Functional characterization of the bladder cancer marker, BLCA-4.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2632771

Sex difference in hepatic peroxisome proliferator-activated receptor alpha expression: influence of pituitary and gonadal hormones

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2632771

Thiazolidinedione activation of peroxisome proliferator-activated receptor gamma can enhance mitochondrial potential and promote cell survival.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2632771

Rodent carcinogenicity with the thiazolidinedione antidiabetic agent troglitazone

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2632771

Troglitazone induces a cellular acidosis by inhibiting acid extrusion in cultured rat mesangial cells

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2632771

Troglitazione affects survival of human osteosarcoma cells

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2632771

Rat PPARs: quantitative analysis in adult rat tissues and regulation in fasting and refeeding.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2632771

(-)3-[4-[2-(Phenoxazin-10-yl)ethoxy]phenyl]-2-ethoxypropanoic acid [(-)DRF 2725]: a dual PPAR agonist with potent antihyperglycemic and lipid modulating activity

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2632771

Drosophila S6 kinase: a regulator of cell size

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2632771

Urothelial tissue culture for bladder reconstruction: an experimental study.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2632771

Effects of pH on the carcinogenicity of o-phenylphenol and sodium o-phenylphenate in the rat urinary bladder

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2632771

Improved skeletal muscle oxidative enzyme activity and restoration of PGC-1α and PPARβ/δ gene expression upon rosiglitazone treatment in obese patients with type 2 diabetes mellitus

4 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1155%2F2008%2F103167

The Transcriptional Coactivator Peroxisome Proliferator Activated Receptor (PPAR) Coactivator-1 and the Nuclear Receptor PPAR Control the Expression of Glycerol Kinase and Metabolism Genes Independently of PPAR Activation in Human White Adipocytes

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1155%2F2008%2F103167

In situ expression of the early growth response gene-1 during murine nephrogenesis

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1155%2F2008%2F103167

Sexual dimorphism in lipid metabolic phenotype associated with old age in Sprague–Dawley rats

21 January 2018

1 reference

12 December 2020

Subchronic urinary bladder effects of muraglitazar in male rats

1 reference

12 December 2020

Acute changes in nucleic acid and protein synthesis in the mouse bladder epithelium induced by three bladder carcinogens

1 reference

12 December 2020

Differential Regulation of Vascular Endothelial Growth Factor Expression by Peroxisome Proliferator-activated Receptors in Bladder Cancer Cells

1 reference

12 December 2020

JTP-426467 acts as a selective antagonist for peroxisome proliferator-activated receptor gamma in vitro and in vivo

1 reference

12 December 2020

Urothelial umbrella cells of human ureter are heterogeneous with respect to their uroplakin composition: different degrees of urothelial maturity in ureter and bladder?

1 reference

12 December 2020

Induction of hyperplasia in the bladder epithelium of rats by a dietary excess of acid or base: implications for toxicity/carcinogenicity testing

1 reference

12 December 2020

Tesaglitazar, a PPARalpha/gamma agonist, induces interstitial mesenchymal cell DNA synthesis and fibrosarcomas in subcutaneous tissues in rats

1 reference

12 December 2020

Altered extracellular matrix expression in the diverted fetal sheep bladder

1 reference

12 December 2020

Transcriptional activation of SHP by PPAR-gamma in liver

1 reference

12 December 2020

Effects of metabolic acidosis on PTH and 1,25(OH)2D3 response to low calcium diet

1 reference

12 December 2020

In situ expression of the early growth response gene-1 during murine nephrogenesis

1 reference

12 December 2020

Comparison of endothelial cell proliferation in normal liver and adipose tissue in B6C3F1 mice, F344 rats, and humans

1 reference

12 December 2020

Expression and prognostic value of Wilms' tumor 1 and early growth response 1 proteins in nephroblastoma

1 reference

12 December 2020

Rat urinary bladder hyperplasia induced by oral administration of carbonic anhydrase inhibitors

1 reference

12 December 2020

Identifiers

DOI

10.1155/2008/103167

1 reference

18 August 2017

1 reference

18 August 2017

1 reference

PMCID

2632771