Ppp1r15 gene knockout reveals an essential role for translation initiation factor 2 alpha (eIF2alpha) dephosphorylation in mammalian development (Q37100863)

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scholarly article

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English	Ppp1r15 gene knockout reveals an essential role for translation initiation factor 2 alpha (eIF2alpha) dephosphorylation in mammalian development	scholarly article

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scholarly article

1 reference

Europe PubMed Central

18 August 2017

Ppp1r15 gene knockout reveals an essential role for translation initiation factor 2 alpha (eIF2alpha) dephosphorylation in mammalian development (English)

1 reference

Europe PubMed Central

18 August 2017

6

1 reference

Europe PubMed Central

18 August 2017

Heather P Harding

object named as

Heather P Harding

1

0 references

Randal J Kaufman

5

object named as

Randal J Kaufman

1 reference

Europe PubMed Central

18 August 2017

Donalyn Scheuner

3

object named as

Donalyn Scheuner

1 reference

Europe PubMed Central

18 August 2017

author name string

Yuhong Zhang

2

1 reference

Europe PubMed Central

18 August 2017

Jane-Jane Chen

4

1 reference

Europe PubMed Central

18 August 2017

language of work or name

0 references

publication date

30 January 2009

1 reference

Europe PubMed Central

18 August 2017

Proceedings of the National Academy of Sciences of the United States of America

1 reference

Europe PubMed Central

18 August 2017

106

1 reference

Europe PubMed Central

18 August 2017

6

1 reference

Europe PubMed Central

18 August 2017

1832-1837

1 reference

Europe PubMed Central

18 August 2017

The TSC1-TSC2 complex: a molecular switchboard controlling cell growth

1 reference

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Ontogeny of erythropoiesis in the mammalian embryo.

1 reference

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Structure and function of the protein kinase R.

1 reference

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Tgf-Beta signaling in development

1 reference

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Regulation of protein synthesis by the heme-regulated eIF2alpha kinase: relevance to anemias

1 reference

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Adaptation to ER stress is mediated by differential stabilities of pro-survival and pro-apoptotic mRNAs and proteins

1 reference

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Double-stranded RNA-dependent protein kinase phosphorylation of the alpha-subunit of eukaryotic translation initiation factor 2 mediates apoptosis

1 reference

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Nutritional control of gene expression: how mammalian cells respond to amino acid limitation

1 reference

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A selective inhibitor of eIF2alpha dephosphorylation protects cells from ER stress

1 reference

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CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum

1 reference

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GADD34-PP1c recruited by Smad7 dephosphorylates TGFbeta type I receptor

1 reference

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Cytoprotection by pre-emptive conditional phosphorylation of translation initiation factor 2

1 reference

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Inhibition of a constitutive translation initiation factor 2alpha phosphatase, CReP, promotes survival of stressed cells

1 reference

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GADD34 induces p53 phosphorylation and p21/WAF1 transcription

1 reference

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Stress-induced gene expression requires programmed recovery from translational repression

1 reference

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14 September 2017

Growth arrest and DNA damage-inducible protein GADD34 targets protein phosphatase 1 alpha to the endoplasmic reticulum and promotes dephosphorylation of the alpha subunit of eukaryotic translation initiation factor 2

1 reference

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Orchestrating the unfolded protein response in health and disease

1 reference

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Heme-regulated eIF2alpha kinase (HRI) is required for translational regulation and survival of erythroid precursors in iron deficiency

1 reference

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Ineffective erythropoiesis in Stat5a(-/-)5b(-/-) mice due to decreased survival of early erythroblasts

1 reference

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Growth arrest and DNA damage-inducible protein GADD34 assembles a novel signaling complex containing protein phosphatase 1 and inhibitor 1.

1 reference

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A germ-line Tsc1 mutation causes tumor development and embryonic lethality that are similar, but not identical to, those caused by Tsc2 mutation in mice

1 reference

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Translational control is required for the unfolded protein response and in vivo glucose homeostasis

1 reference

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Diabetes mellitus and exocrine pancreatic dysfunction in perk-/- mice reveals a role for translational control in secretory cell survival

1 reference

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Feedback inhibition of the unfolded protein response by GADD34-mediated dephosphorylation of eIF2alpha

1 reference

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Regulation of antioxidant metabolism by translation initiation factor 2alpha

1 reference

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E2F4 is essential for normal erythrocyte maturation and neonatal viability

1 reference

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Fetal anemia and apoptosis of red cell progenitors in Stat5a-/-5b-/- mice: a direct role for Stat5 in Bcl-X(L) induction

1 reference

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Renal carcinogenesis, hepatic hemangiomatosis, and embryonic lethality caused by a germ-line Tsc2 mutation in mice

1 reference

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Targeted disruption of the ubiquitous CNC-bZIP transcription factor, Nrf-1, results in anemia and embryonic lethality in mice

1 reference

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The phosphorylation state of eucaryotic initiation factor 2 alters translational efficiency of specific mRNAs

1 reference

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Gadd34 requirement for normal hemoglobin synthesis

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Delineation of a negative feedback regulatory loop that controls protein translation during endoplasmic reticulum stress

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Phosphorylation of eukaryotic translation initiation factor 2 mediates apoptosis in response to activation of the double-stranded RNA-dependent protein kinase

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Transcript profiling during preimplantation mouse development.

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1 reference

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12 December 2020

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10.1073/PNAS.0809632106

1 reference

Europe PubMed Central

18 August 2017

2009PNAS..106.1832H

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1 reference

Europe PubMed Central

18 August 2017

1 reference

Europe PubMed Central

18 August 2017

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