Tumor necrosis factor promotes Runx2 degradation through up-regulation of Smurf1 and Smurf2 in osteoblasts. (Q37109228)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16373342%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

title

Tumor necrosis factor promotes Runx2 degradation through up-regulation of Smurf1 and Smurf2 in osteoblasts (English)

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14 January 2020

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6

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14 January 2020

author name string

Hiroyuki Kaneki

1

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14 January 2020

Ruolin Guo

2

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14 January 2020

Di Chen

3

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14 January 2020

Zhenqiang Yao

4

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14 January 2020

Edward M Schwarz

5

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14 January 2020

Brendan F Boyce

7

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14 January 2020

Lianping Xing

8

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14 January 2020

language of work or name

English

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publication date

22 December 2005

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Journal of Biological Chemistry

14 January 2020

published in

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14 January 2020

volume

281

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14 January 2020

issue

7

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14 January 2020

page(s)

4326-4333

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Ubiquitin ligase Smurf1 controls osteoblast activity and bone homeostasis by targeting MEKK2 for degradation

14 January 2020

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TNF-alpha acts via p38 MAPK to stimulate expression of the ubiquitin ligase atrogin1/MAFbx in skeletal muscle

14 September 2017

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The p55 TNF receptor mediates TNF inhibition of osteoblast differentiation independently of apoptosis

14 September 2017

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14 September 2017

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Smurf1 inhibits osteoblast differentiation and bone formation in vitro and in vivo

14 September 2017

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Regulation of cell polarity and protrusion formation by targeting RhoA for degradation

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Smurf1 facilitates myogenic differentiation and antagonizes the bone morphogenetic protein-2-induced osteoblast conversion by targeting Smad5 for degradation

14 September 2017

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14 September 2017

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Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF beta receptor for degradation

14 September 2017

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Regulation of Smad degradation and activity by Smurf2, an E3 ubiquitin ligase

14 September 2017

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Genetic evidence for a role for Src family kinases in TNF family receptor signaling and cell survival

14 September 2017

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Smurf2 is a ubiquitin E3 ligase mediating proteasome-dependent degradation of Smad2 in transforming growth factor-beta signaling

14 September 2017

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Advances in our understanding of the bone and joint pathology caused by Staphylococcus aureus infection.

14 September 2017

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Pathogenesis of bone erosions in rheumatoid arthritis

14 September 2017

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Tumor necrosis factor-alpha and interleukin-1beta increase the Fas-mediated apoptosis of human osteoblasts

14 September 2017

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A SMAD ubiquitin ligase targets the BMP pathway and affects embryonic pattern formation

14 September 2017

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Estrogen decreases TNF gene expression by blocking JNK activity and the resulting production of c-Jun and JunD.

14 September 2017

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Transgenic mice expressing human tumour necrosis factor: a predictive genetic model of arthritis

14 September 2017

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Effects of interleukin-1 beta and tumor necrosis factor-alpha on osteoblastic expression of osteocalcin and mineralized extracellular matrix in vitro

14 September 2017

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E3 Ubiquitin Ligase Smurf1 Mediates Core-binding Factor α1/Runx2 Degradation and Plays A Specific Role in Osteoblast Differentiation

14 September 2017

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29 September 2017

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29 September 2017

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Induction of apoptosis in murine clonal osteoblasts expressed by human T-cell leukemia virus type I tax by NF-kappa B and TNF-alpha

29 September 2017

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3 September 2018

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Expression of the osteoblast differentiation factor RUNX2 (Cbfa1/AML3/Pebp2alpha A) is inhibited by tumor necrosis factor-alpha

3 September 2018

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3 September 2018

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12 December 2020

Tumor necrosis factor-alpha inhibits pre-osteoblast differentiation through its type-1 receptor

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12 December 2020

Ceramide-induced nuclear translocation of NF-kappa B is a potential mediator of the apoptotic response to TNF-alpha in murine clonal osteoblasts

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12 December 2020

Ubiquitin-mediated degradation a mechanism for fine-tuning TGF-beta signaling

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12 December 2020

Identifiers

DOI

10.1074/JBC.M509430200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16373342%20AND%20SRC:MED&resulttype=core&format=json

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14 January 2020

Fatcat ID

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24 November 2022

mapped directly with Wikidata item

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16373342%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

PubMed publication ID

16373342

1 reference