GATA1-related leukaemias (Q37114562)

18 August 2017

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title

GATA1-related leukaemias (English)

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18 August 2017

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Ritsuko Shimizu

1

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18 August 2017

James Douglas Engel

series ordinal

2

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18 August 2017

Masayuki Yamamoto

series ordinal

3

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18 August 2017

language of work or name

English

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publication date

1 April 2008

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18 August 2017

Nature Reviews Cancer

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18 August 2017

8

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18 August 2017

4

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18 August 2017

279-287

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https://scigraph.springernature.com/pub.10.1038/nrc2348

18 August 2017

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cites work

Myeloid lineage commitment from the hematopoietic stem cell

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Transcription factor fusions in acute leukemia: variations on a theme.

31 March 2020

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A minigene containing four discrete cis elements recapitulates GATA-1 gene expression in vivo

31 March 2020

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Molecular evolution of the GATA family of transcription factors: conservation within the DNA-binding domain

31 March 2020

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Transcriptional regulation of erythropoiesis: an affair involving multiple partners

31 March 2020

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The GATA family (vertebrates and invertebrates).

31 March 2020

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The zinc finger-containing transcription factors GATA-4, -5, and -6. Ubiquitously expressed regulators of tissue-specific gene expression.

31 March 2020

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GATA-5: a transcriptional activator expressed in a novel temporally and spatially-restricted pattern during embryonic development

31 March 2020

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T helper cell differentiation: on again, off again

31 March 2020

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Gene expression regulation and domain function of hematopoietic GATA factors

31 March 2020

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Developmental control via GATA factor interplay at chromatin domains

31 March 2020

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In vivo requirements for GATA-1 functional domains during primitive and definitive erythropoiesis

31 March 2020

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GATA-4 incompletely substitutes for GATA-1 in promoting both primitive and definitive erythropoiesis in vivo.

31 March 2020

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GATA-1-mediated proliferation arrest during erythroid maturation.

31 March 2020

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Familial dyserythropoietic anaemia and thrombocytopenia due to an inherited mutation in GATA1

31 March 2020

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X-linked thrombocytopenia caused by a novel mutation of GATA-1

31 March 2020

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Platelet characteristics in patients with X-linked macrothrombocytopenia because of a novel GATA1 mutation

31 March 2020

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Different substitutions at residue D218 of the X-linked transcription factor GATA1 lead to altered clinical severity of macrothrombocytopenia and anemia and are associated with variable skewed X inactivation

31 March 2020

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X-linked thrombocytopenia with thalassemia from a mutation in the amino finger of GATA-1 affecting DNA binding rather than FOG-1 interaction

31 March 2020

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Congenital erythropoietic porphyria due to a mutation in GATA1: the first trans-acting mutation causative for a human porphyria

31 March 2020

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Erythroid transcription factor GATA-1 is abundantly transcribed in mouse testis

31 March 2020

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Arrest in primitive erythroid cell development caused by promoter-specific disruption of the GATA-1 gene

31 March 2020

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Arrested development of embryonic red cell precursors in mouse embryos lacking transcription factor GATA-1

31 March 2020

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Gene action in the X-chromosome of the mouse (Mus musculus L.)

31 March 2020

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Leukemogenesis caused by incapacitated GATA-1 function

31 March 2020

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GATA-1 transcription is controlled by distinct regulatory mechanisms during primitive and definitive erythropoiesis

31 March 2020

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A GATA box in the GATA-1 gene hematopoietic enhancer is a critical element in the network of GATA factors and sites that regulate this gene

31 March 2020

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Regulation of GATA1 gene expression

31 March 2020

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Identification and characterization of 2 types of erythroid progenitors that express GATA-1 at distinct levels

31 March 2020

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Disruption of the Cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and blocks definitive hematopoiesis

31 March 2020

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Haploinsufficiency of CBFA2 causes familial thrombocytopenia with propensity to develop acute myelogenous leukaemia

31 March 2020

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AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis

31 March 2020

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Runx1 protects hematopoietic stem/progenitor cells from oncogenic insult

31 March 2020

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The key role of PU.1/SPI-1 in B cells, myeloid cells and macrophages.

31 March 2020

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Requirement of transcription factor PU.1 in the development of multiple hematopoietic lineages.

31 March 2020

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PU.1 regulates the commitment of adult hematopoietic progenitors and restricts granulopoiesis

31 March 2020

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A distal single nucleotide polymorphism alters long-range regulation of the PU.1 gene in acute myeloid leukemia.

31 March 2020

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Acute myeloid leukemia induced by graded reduction of a lineage-specific transcription factor, PU.1.

31 March 2020

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Inactivation of PU.1 in adult mice leads to the development of myeloid leukemia

31 March 2020

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In vitro development of primitive and definitive erythrocytes from different precursors

31 March 2020

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Graded levels of GATA-1 expression modulate survival, proliferation, and differentiation of erythroid progenitors

31 March 2020

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Transcription factor GATA-2 gene is located near 3q21 breakpoints in myeloid leukemia.

31 March 2020

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Mutations in GATA1 in both transient myeloproliferative disorder and acute megakaryoblastic leukemia of Down syndrome

31 March 2020

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Mutations in exon 2 of GATA1 are early events in megakaryocytic malignancies associated with trisomy 21

31 March 2020

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Frequent mutations in the GATA-1 gene in the transient myeloproliferative disorder of Down syndrome

31 March 2020

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Fetal origin of the GATA1 mutation in identical twins with transient myeloproliferative disorder and acute megakaryoblastic leukemia accompanying Down syndrome

31 March 2020

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31 March 2020

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Transient leukaemia--a benign form of leukaemia in newborn infants with trisomy 21.

31 March 2020

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Origins of leukaemia in children with Down syndrome

31 March 2020

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The GATA1 mutation in an adult patient with acute megakaryoblastic leukemia not accompanying Down syndrome.

31 March 2020

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Natural history of GATA1 mutations in Down syndrome

31 March 2020

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GATA1 mutations in transient leukemia and acute megakaryoblastic leukemia of Down syndrome

31 March 2020

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Development of acute megakaryoblastic leukemia from a minor clone in a Down syndrome patient with clinically overt transient myeloproliferative disorder

31 March 2020

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Acute megakaryoblastic leukemia after transient myeloproliferative disorder with clonal karyotype evolution in a phenotypically normal neonate

31 March 2020

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Risk for leukemia in infants without Down syndrome who have transient myeloproliferative disorder

31 March 2020

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Murine models for Down syndrome

31 March 2020

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Chromosome 21 and down syndrome: from genomics to pathophysiology

31 March 2020

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Craniofacial phenotypes in segmentally trisomic mouse models for Down syndrome.

31 March 2020

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A mouse model for Down syndrome exhibits learning and behaviour deficits.

31 March 2020

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Postnatal lethality and cardiac anomalies in the Ts65Dn Down syndrome mouse model

31 March 2020

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Highly penetrant myeloproliferative disease in the Ts65Dn mouse model of Down syndrome

31 March 2020

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Hematological abnormalities during the first week of life among neonates with Down syndrome: data from a multihospital healthcare system

31 March 2020

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Hematopoietic progenitor cell deficiency in fetuses and children affected by Down's syndrome

31 March 2020

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Transgenic expression of BACH1 transcription factor results in megakaryocytic impairment

31 March 2020

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Characterization of GATA-1(+) hemangioblastic cells in the mouse embryo

31 March 2020

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GATA1-mediated megakaryocyte differentiation and growth control can be uncoupled and mapped to different domains in GATA1

31 March 2020

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Differential requirements for the activation domain and FOG-interaction surface of GATA-1 in megakaryocyte gene expression and development

31 March 2020

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GATA-factor dependence of the multitype zinc-finger protein FOG-1 for its essential role in megakaryopoiesis

31 March 2020

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Transgenic rescue of GATA-1-deficient mice with GATA-1 lacking a FOG-1 association site phenocopies patients with X-linked thrombocytopenia

31 March 2020

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Fetal and neonatal leukemia

31 March 2020

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Developmental stage-selective effect of somatically mutated leukemogenic transcription factor GATA1

31 March 2020

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The balance between heritable and environmental aetiology of human disease

31 March 2020

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Activity and tissue-specific expression of the transcription factor NF-E1 multigene family

31 March 2020

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Combinatorial Gata2 and Sca1 expression defines hematopoietic stem cells in the bone marrow niche

31 March 2020

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A Gata2 intronic enhancer confers its pan-endothelia-specific regulation.

31 March 2020

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Targeted disruption of the GATA3 gene causes severe abnormalities in the nervous system and in fetal liver haematopoiesis

31 March 2020

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GATA-1: one protein, many partners.

31 March 2020

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A palindromic regulatory site within vertebrate GATA-1 promoters requires both zinc fingers of the GATA-1 DNA-binding domain for high-affinity interaction

31 March 2020

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GATA-1-dependent transcriptional repression of GATA-2 via disruption of positive autoregulation and domain-wide chromatin remodeling

31 March 2020

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GATA motifs regulate early hematopoietic lineage-specific expression of the Gata2 gene

31 March 2020

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Ineffective erythropoiesis in Stat5a(-/-)5b(-/-) mice due to decreased survival of early erythroblasts

31 March 2020

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Mechanisms of differential transferrin receptor expression in normal hematopoiesis

31 March 2020

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The monoclonal antibody TER-119 recognizes a molecule associated with glycophorin A and specifically marks the late stages of murine erythroid lineage

31 March 2020

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Conserved structure, regulatory elements, and transcriptional regulation from the GATA-1 gene testis promoter

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/NRC2348

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18 August 2017

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