Hypoxia in adipose tissue: a basis for the dysregulation of tissue function in obesity? (Q37132401)

18 August 2017

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title

Hypoxia in adipose tissue: a basis for the dysregulation of tissue function in obesity? (English)

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18 August 2017

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Paul Trayhurn

1

1 reference

PubMed ID

18397542

18 August 2017

Bohan Wang

series ordinal

2

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PubMed ID

18397542

18 August 2017

I Stuart Wood

series ordinal

3

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18 August 2017

9 April 2008

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British Journal of Nutrition

18 August 2017

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18 August 2017

100

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18 August 2017

227-235

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18 August 2017

2

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Expression of metallothionein-III induced by hypoxia attenuates hypoxia-induced cell death in vitro

18 August 2017

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

Metallothionein gene expression in human adipose tissue from lean and obese subjects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

PCR arrays identify metallothionein-3 as a highly hypoxia-inducible gene in human adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

Reduction of macrophage infiltration and chemoattractant gene expression changes in white adipose tissue of morbidly obese subjects after surgery-induced weight loss

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

HIF-1 regulates hypoxia- and insulin-induced expression of apelin in adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

Hypoxic induction of human visfatin gene is directly mediated by hypoxia-inducible factor-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

Dysregulation of the expression and secretion of inflammation-related adipokines by hypoxia in human adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

Visfatin in adipocytes is upregulated by hypoxia through HIF1alpha-dependent mechanism

21 January 2018

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https://api.crossref.org/works/10.1017%2FS0007114508971282

Hypoxia dysregulates the production of adiponectin and plasminogen activator inhibitor-1 independent of reactive oxygen species in adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

Adiponectin gene expression is inhibited by beta-adrenergic stimulation via protein kinase A in 3T3-L1 adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

Expression of ob gene in adipose cells. Regulation by insulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

Adipose tissue hypoxia in obesity and its impact on adipocytokine dysregulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

Sequence and structure of a human glucose transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

Hypoxia is a potential risk factor for chronic inflammation and adiponectin reduction in adipose tissue of ob/ob and dietary obese mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

Gene regulation under low oxygen: holding your breath for transcription.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

Hypoxia-responsive transcription factors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

Regulation of oxygen sensing by ion channels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

HIFs and tumors--causes and consequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

HIF-1 and mechanisms of hypoxia sensing

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

Tissue oxygenation in obese and non-obese patients during laparoscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

Tissue oxygen tension and brain sensitivity to hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

Retinal degeneration and local oxygen metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

Targeting HIF-1 for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

Why do cancers have high aerobic glycolysis?

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

Oxygen, a source of life and stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

Relationship between adipocyte size and adipokine expression and secretion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

Impaired postprandial adipose tissue blood flow response is related to aspects of insulin sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

Obesity decreases perioperative tissue oxygenation

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

Chemokines control fat accumulation and leptin secretion by cultured human adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

Activation of hypoxia-inducible factor 1 during macrophage differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

Mitochondrial reactive oxygen species control the transcription factor CHOP-10/GADD153 and adipocyte differentiation: a mechanism for hypoxia-dependent effect

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

Hypoxia selectively inhibits monocyte chemoattractant protein-1 production by macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

Release of interleukins and other inflammatory cytokines by human adipose tissue is enhanced in obesity and primarily due to the nonfat cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

Comparison of the release of adipokines by adipose tissue, adipose tissue matrix, and adipocytes from visceral and subcutaneous abdominal adipose tissues of obese humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

Regulation of protein synthesis by hypoxia via activation of the endoplasmic reticulum kinase PERK and phosphorylation of the translation initiation factor eIF2alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

Reactive oxygen species have a causal role in multiple forms of insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

Thematic review series: Adipocyte Biology. Adipocyte stress: the endoplasmic reticulum and metabolic disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

Intermittent hypoxia causes insulin resistance in lean mice independent of autonomic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

Obesity is associated with macrophage accumulation in adipose tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

Intermittent hypoxia increases insulin resistance in genetically obese mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

Hypoxia causes glucose intolerance in humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

Hypoxia increases expression of selective facilitative glucose transporters (GLUT) and 2-deoxy-D-glucose uptake in human adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

Inflammation and metabolic disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

Expression of Class III facilitative glucose transporter genes (GLUT-10 and GLUT-12) in mouse and human adipose tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

Glucose transporters (GLUT and SGLT): expanded families of sugar transport proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

Proliferation and differentiation of bone marrow stromal cells under hypoxic conditions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

Differentiation arrest by hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

Hypoxia inhibits adipocyte differentiation in a HDAC-independent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

Hypoxia inhibition of adipocytogenesis in human bone marrow stromal cells requires transforming growth factor-beta/Smad3 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

Inhibition of PPAR gamma 2 gene expression by the HIF-1-regulated gene DEC1/Stra13: a mechanism for regulation of adipogenesis by hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

The adipocyte-secreted protein Acrp30 enhances hepatic insulin action

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

Adiponectin, an adipocyte-derived plasma protein, inhibits endothelial NF-kappaB signaling through a cAMP-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

Novel modulator for endothelial adhesion molecules: adipocyte-derived plasma protein adiponectin

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

Angiopoietin-like 4 is a proangiogenic factor produced during ischemia and in conventional renal cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

Leptin, the product of Ob gene, promotes angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

Biological action of leptin as an angiogenic factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

Severely impaired adipsin expression in genetic and acquired obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

Adipsin: a circulating serine protease homolog secreted by adipose tissue and sciatic nerve

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

Positional cloning of the mouse obese gene and its human homologue

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

Adipocytes as regulators of energy balance and glucose homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

Adipokines: inflammation and the pleiotropic role of white adipose tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

Adipose tissue as an endocrine organ

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

Minireview: The adipocyte--at the crossroads of energy homeostasis, inflammation, and atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

Preadipocytes mediate lipopolysaccharide-induced inflammation and insulin resistance in primary cultures of newly differentiated human adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

7 January 2021

Expression of interleukin-6 is greater in preadipocytes than in adipocytes of 3T3-L1 cells and C57BL/6J and ob/ob mice

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

7 January 2021

Macrophage responses to hypoxia: relevance to disease mechanisms.

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

7 January 2021

The effect of altitude hypoxia on glucose homeostasis in men

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

7 January 2021

Regulation of leptin production: a dominant role for the sympathetic nervous system?

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

7 January 2021

Regional blood flow in genetically obese (ob/ob) mice. The importance of brown adipose tissue to the reduced energy expenditure on non-shivering thermogenesis

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

7 January 2021

Cancer: looking outside the genome

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

7 January 2021

Glucose uptake and perfusion in subcutaneous and visceral adipose tissue during insulin stimulation in nonobese and obese humans

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

7 January 2021

Effects of hypoxia on the expression of proangiogenic factors in differentiated 3T3-F442A adipocytes

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

7 January 2021

Inflammation, stress, and diabetes

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

7 January 2021

Adipocyte blood flow is decreased in obese Zucker rats

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

7 January 2021

Expression and secretion of inflammation-related adipokines by human adipocytes differentiated in culture: integrated response to TNF-alpha

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

7 January 2021

Physiological role of adipose tissue: white adipose tissue as an endocrine and secretory organ.

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

7 January 2021

Hypoxia inducible factor regulates the cardiac expression and secretion of apelin

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

7 January 2021

Production and release of macrophage migration inhibitory factor from human adipocytes

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

7 January 2021

Relationship of adipose tissue blood flow to fat cell size and number.

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

7 January 2021

Vascular endothelial growth factor is the major angiogenic factor in omentum: mechanism of the omentum-mediated angiogenesis

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

7 January 2021

Adipose tissue, insulin action and vascular disease: inflammatory signals

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

7 January 2021

Comparison of tumor and normal tissue oxygen tension measurements using OxyLite or microelectrodes in rodents

1 reference

https://api.crossref.org/works/10.1017%2FS0007114508971282

7 January 2021

10.1017/S0007114508971282

Identifiers

DOI

1 reference

18 August 2017

1 reference

PubMed ID

18397542