Oxygen, a source of life and stress (Q36857204)

16 August 2017

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title

Oxygen, a source of life and stress (English)

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16 August 2017

2

Jacques Pouysségur

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16 August 2017

M Christiane Brahimi-Horn

series ordinal

1

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PubMed ID

17586500

16 August 2017

language of work or name

English

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publication date

19 June 2007

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16 August 2017

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16 August 2017

581

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16 August 2017

19

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16 August 2017

3582-3591

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Altitude is a phenotypic modifier in hereditary paraganglioma type 1: evidence for an oxygen-sensing defect

16 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.06.018

Angiogenesis as a therapeutic target

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.06.018

Retinal degeneration and local oxygen metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.06.018

Tissue oxygen tension and brain sensitivity to hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.06.018

Why do cancers have high aerobic glycolysis?

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.06.018

Tumor microenvironmental physiology and its implications for radiation oncology

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.06.018

Hypoxia and glucose metabolism in malignant tumors: evaluation by [18F]fluoromisonidazole and [18F]fluorodeoxyglucose positron emission tomography imaging

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.06.018

Hypoxia-inducible nuclear factors bind to an enhancer element located 3' to the human erythropoietin gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.06.018

The hypoxia-inducible-factor hydroxylases bring fresh air into hypoxia signalling

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.06.018

Signalling hypoxia by HIF hydroxylases

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.06.018

Signalling via the hypoxia-inducible factor-1alpha requires multiple posttranslational modifications

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.06.018

RACK1 vs. HSP90: competition for HIF-1 alpha degradation vs. stabilization

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.06.018

Induction of the heat shock pathway during hypoxia requires regulation of heat shock factor by hypoxia-inducible factor-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.06.018

Target gene selectivity of hypoxia-inducible factor-alpha in renal cancer cells is conveyed by post-DNA-binding mechanisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.06.018

Regulation of HIF prolyl hydroxylases by hypoxia-inducible factors

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.06.018

HIF-2alpha promotes hypoxic cell proliferation by enhancing c-myc transcriptional activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.06.018

Hypoxia-inducible factor-2 (HIF-2) regulates hepatic erythropoietin in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.06.018

The hypoxia-inducible factor and tumor progression along the angiogenic pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.06.018

The oxygen sensor factor-inhibiting hypoxia-inducible factor-1 controls expression of distinct genes through the bifunctional transcriptional character of hypoxia-inducible factor-1alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.06.018

Attenuation of LDH-A expression uncovers a link between glycolysis, mitochondrial physiology, and tumor maintenance

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.06.018

Evaluation of myc E-box phylogenetic footprints in glycolytic genes by chromatin immunoprecipitation assays

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.06.018

Coordination and communication between the p53 and IGF-1-AKT-TOR signal transduction pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.06.018

Akt-dependent transformation: there is more to growth than just surviving

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.06.018

TIGAR, a p53-inducible regulator of glycolysis and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.06.018

HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.06.018

HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.06.018

HIF-1 regulates cytochrome oxidase subunits to optimize efficiency of respiration in hypoxic cells

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.06.018

p53 regulates mitochondrial respiration

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.06.018

HIF-1 inhibits mitochondrial biogenesis and cellular respiration in VHL-deficient renal cell carcinoma by repression of C-MYC activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.06.018

Hypoxia-inducible factor 2alpha regulates expression of the mitochondrial aconitase chaperone protein frataxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.06.018

The mammalian target of rapamycin (mTOR) pathway regulates mitochondrial oxygen consumption and oxidative capacity

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.06.018

Hypoxia signalling in cancer and approaches to enforce tumour regression

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.06.018

Ras, PI(3)K and mTOR signalling controls tumour cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.06.018

Structural and mechanistic studies on the inhibition of the hypoxia-inducible transcription factor hydroxylases by tricarboxylic acid cycle intermediates

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.06.018

Mitochondrial tumour suppressors: a genetic and biochemical update

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.06.018

Cell-permeating alpha-ketoglutarate derivatives alleviate pseudohypoxia in succinate dehydrogenase-deficient cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.06.018

Targeted inactivation of fh1 causes proliferative renal cyst development and activation of the hypoxia pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.06.018

Proline hydroxylation and gene expression

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.06.018

JunD reduces tumor angiogenesis by protecting cells from oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.06.018

The role of disturbed pH dynamics and the Na+/H+ exchanger in metastasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.06.018

The expanding family of eucaryotic Na(+)/H(+) exchangers

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.06.018

The plasma membrane lactate transporter MCT4, but not MCT1, is up-regulated by hypoxia through a HIF-1alpha-dependent mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.06.018

HIF-1 regulates hypoxic induction of NHE1 expression and alkalinization of intracellular pH in pulmonary arterial myocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.06.018

The NHERF1 PDZ2 domain regulates PKA-RhoA-p38-mediated NHE1 activation and invasion in breast tumor cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.06.018

Expression of hypoxia-inducible cell-surface transmembrane carbonic anhydrases in human cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.06.018

Regulation of tumor pH and the role of carbonic anhydrase 9.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.06.018

Angiogenesis and hypoxia in lymph node metastases is predicted by the angiogenesis and hypoxia in the primary tumour in patients with breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.06.018

HIF-1alpha and CA IX staining in invasive breast carcinomas: prognosis and treatment outcome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.06.018

Hypoxia-regulated carbonic anhydrase IX expression is associated with poor survival in patients with invasive breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.06.018

Transport activity of MCT1 expressed in Xenopus oocytes is increased by interaction with carbonic anhydrase

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.06.018

Identification of membrane type-1 matrix metalloproteinase as a target of hypoxia-inducible factor-2 alpha in von Hippel-Lindau renal cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.06.018

Lactate: mirror and motor of tumor malignancy

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.06.018

Hypoxia promotes invasive growth by transcriptional activation of the met protooncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.06.018

Chemokine receptor CXCR4 downregulated by von Hippel-Lindau tumour suppressor pVHL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.06.018

Autocrine motility factor signaling enhances pancreatic cancer metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.06.018

The role of hypoxia inducible factor 1 (HIF-1) in hypoxia induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.06.018

Targeting HIF-1 for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.06.018

BNip3 and signal-specific programmed death in the heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.06.018

Hypoxia and acidosis activate cardiac myocyte death through the Bcl-2 family protein BNIP3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.06.018

Death by design: apoptosis, necrosis and autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.06.018

Glycolysis inhibition for anticancer treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2007.06.018

10.1016/J.FEBSLET.2007.06.018

21 January 2018

Identifiers

DOI

1 reference

16 August 2017

1 reference

PubMed ID

17586500