Role of stearoyl-CoA desaturases in obesity and the metabolic syndrome (Q37144096)

18 August 2017

1 reference

title

Role of stearoyl-CoA desaturases in obesity and the metabolic syndrome (English)

1 reference

18 August 2017

0 references

1 reference

H E Popeijus

1

1 reference

18 August 2017

W H M Saris

series ordinal

2

1 reference

18 August 2017

R P Mensink

series ordinal

3

1 reference

18 August 2017

language of work or name

English

0 references

publication date

22 April 2008

1 reference

International Journal of Obesity

18 August 2017

1 reference

18 August 2017

32

1 reference

18 August 2017

7

1 reference

18 August 2017

1076-1082

1 reference

https://scigraph.springernature.com/pub.10.1038/ijo.2008.55

18 August 2017

0 references

cites work

Overweight and obesity: prevalence, consequences, and causes of a growing public health problem

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.55

Increases in morbid obesity in the USA: 2000-2005

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.55

The epidemiology of obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.55

Dietary energy density is associated with obesity and the metabolic syndrome in U.S. adults.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.55

Regulation of gene expression by dietary fat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.55

Substituting dietary saturated fat with polyunsaturated fat changes abdominal fat distribution and improves insulin sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.55

Substituting dietary saturated for monounsaturated fat impairs insulin sensitivity in healthy men and women: The KANWU Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.55

Plasma fatty acid composition and incidence of coronary heart disease in middle aged adults: the Atherosclerosis Risk in Communities (ARIC) Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.55

Peroxisome proliferator activator receptor gamma coactivator-1 expression is reduced in obesity: potential pathogenic role of saturated fatty acids and p38 mitogen-activated protein kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.55

PGC-1alpha: a potent transcriptional cofactor involved in the pathogenesis of type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.55

PGC-1 coactivators: inducible regulators of energy metabolism in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.55

Membrane topology of mouse stearoyl-CoA desaturase 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.55

Purification and properties of rat liver microsomal stearyl coenzyme A desaturase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.55

Troglitazone increases the number of small adipocytes without the change of white adipose tissue mass in obese Zucker rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.55

C. elegans feeding defective mutants have shorter body lengths and increased autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.55

Cold-induced expression of delta 9-desaturase in carp by transcriptional and posttranslational mechanisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.55

Partial characterization of a cDNA for human stearoyl-CoA desaturase and changes in its mRNA expression in some normal and malignant tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.55

Stearoyl-CoA desaturase mRNA is transcribed from a single gene in the ovine genome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.55

The P-OLE1 gene of Pichia angusta encodes a delta 9-fatty acid desaturase and complements the ole1 mutation of Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.55

Sequence analysis and characterization of FAR-17c, an androgen-dependent gene in the flank organs of hamsters

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.55

Identification and characterization of murine SCD4, a novel heart-specific stearoyl-CoA desaturase isoform regulated by leptin and dietary factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.55

Scd3--a novel gene of the stearoyl-CoA desaturase family with restricted expression in skin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.55

Identification of mouse palmitoyl-coenzyme A Delta9-desaturase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.55

Stearoyl-CoA desaturase-2 gene expression is required for lipid synthesis during early skin and liver development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.55

Human stearoyl-CoA desaturase: alternative transcripts generated from a single gene by usage of tandem polyadenylation sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.55

Characterization of HSCD5, a novel human stearoyl-CoA desaturase unique to primates

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.55

Characterization of human SCD2, an oligomeric desaturase with improved stability and enzyme activity by cross-linking in intact cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.55

Elevated stearoyl-CoA desaturase-1 expression in skeletal muscle contributes to abnormal fatty acid partitioning in obese humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.55

Identification of Ras-related nuclear protein, targeting protein for xenopus kinesin-like protein 2, and stearoyl-CoA desaturase 1 as promising cancer targets from an RNAi-based screen.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.55

Regulation of stearoyl-CoA desaturase-1 after central and peripheral nerve lesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.55

Eight histidine residues are catalytically essential in a membrane-associated iron enzyme, stearoyl-CoA desaturase, and are conserved in alkane hydroxylase and xylene monooxygenase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.55

The evolution of desaturases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.55

Control of fatty acid desaturation: a mechanism conserved from bacteria to humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.55

Isolation and characterization of the human stearoyl-CoA desaturase gene promoter: requirement of a conserved CCAAT cis-element

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.55

Cloning and characterization of the human stearoyl-CoA desaturase gene promoter: transcriptional activation by sterol regulatory element binding protein and repression by polyunsaturated fatty acids and cholesterol

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.55

Peroxisome proliferators induce mouse liver stearoyl-CoA desaturase 1 gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.55

Rosiglitazone increases indexes of stearoyl-CoA desaturase activity in humans: link to insulin sensitization and the role of dominant-negative mutation in peroxisome proliferator-activated receptor-gamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.55

Effects of fenofibrate and insulin on the biosynthesis of unsaturated fatty acids in streptozotocin diabetic rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.55

Degradation of stearoyl-coenzyme A desaturase: endoproteolytic cleavage by an integral membrane protease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.55

The N terminus of microsomal delta 9 stearoyl-CoA desaturase contains the sequence determinant for its rapid degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.55

Ubiquitin-proteasome-dependent degradation of mammalian ER stearoyl-CoA desaturase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.55

Selective mutagenesis of lysyl residues leads to a stable and active form of delta 9 stearoyl-CoA desaturase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.55

Degradation of hepatic stearyl CoA delta 9-desaturase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.55

A microsomal endopeptidase from liver that preferentially degrades stearoyl-CoA desaturase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.55

A plasminogen-like protein selectively degrades stearoyl-CoA desaturase in liver microsomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.55

High stearoyl-CoA desaturase protein and activity levels in simian virus 40 transformed-human lung fibroblasts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.55

The role of desaturases in cold-induced lipid restructuring

21 January 2018

2 references

https://api.crossref.org/works/10.1038%2FIJO.2008.55

21 January 2018

https://api.crossref.org/works/10.1038%2FIJO.2008.55

7 January 2021

Characterization of delta 9 acyl-lipid desaturase homologues from Arabidopsis thaliana.

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.55

CHILLING SENSITIVITY IN PLANTS AND CYANOBACTERIA: The Crucial Contribution of Membrane Lipids

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.55

Overweight, Obesity, and Mortality from Cancer in a Prospectively Studied Cohort of U.S. Adults

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.55

The obesity-cancer link: lessons learned from a fatless mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.55

Loss of stearoyl-CoA desaturase expression is a frequent event in prostate carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.55

Fatty acid synthase and cancer: new application of an old pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.55

Inhibition of fatty acid synthase activity in prostate cancer cells by dutasteride

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.55

Role for stearoyl-CoA desaturase-1 in leptin-mediated weight loss

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.55

Loss of stearoyl-CoA desaturase-1 function protects mice against adiposity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.55

Loss of stearoyl-CoA desaturase-1 improves insulin sensitivity in lean mice but worsens diabetes in leptin-deficient obese mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.55

Prevention of obesity in mice by antisense oligonucleotide inhibitors of stearoyl-CoA desaturase-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.55

Diet-induced changes in stearoyl-CoA desaturase 1 expression in obesity-prone and -resistant mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.55

Effects of leptin, troglitazone, and dietary fat on stearoyl CoA desaturase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.55

Regulation by carbohydrate and clofibric acid of palmitoyl-CoA chain elongation in the liver of rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.55

Analysis of the contribution to type 2 diabetes susceptibility of sequence variation in the gene encoding stearoyl-CoA desaturase, a key regulator of lipid and carbohydrate metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.55

'Striking the Right Balance' in Targeting PPARgamma in the Metabolic Syndrome: Novel Insights from Human Genetic Studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.55

Mucor rouxiiΔ9-Desaturase Gene Is Transcriptionally Regulated during Cell Growth and by Low Temperature

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.55

Obesity is associated with increased risks of prostate cancer metastasis and death after initial cancer diagnosis in middle-aged men

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.55

Prevalence of overweight and obesity in the Netherlands

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.55

7 January 2021

Dietary energy density is associated with overweight status among 5 ethnic groups in the multiethnic cohort study

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.55

7 January 2021

Daily physical activity counts vs structured activity counts in lean and overweight Dutch children

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.55

7 January 2021

Human stearoyl-CoA desaturase: alternative transcripts generated from a single gene by usage of tandem polyadenylation sites

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.55

7 January 2021

Differential expression of cold- and diet-specific genes encoding two carp liver delta 9-acyl-CoA desaturase isoforms

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.55

7 January 2021

The temperature-dependent expression of the desaturase gene desA in Synechocystis PCC6803

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.55

7 January 2021

Immunohistochemical detection of a fatty acid synthase (OA-519) as a predictor of progression of prostate cancer

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.55

7 January 2021

Stearoyl CoA desaturase 1 is elevated in obesity but protects against fatty acid-induced skeletal muscle insulin resistance in vitro

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.55

7 January 2021

Polymorphisms in the SCD1 gene: associations with body fat distribution and insulin sensitivity.

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.55

7 January 2021

Inhibition of RXR and PPARgamma ameliorates diet-induced obesity and type 2 diabetes

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.55

7 January 2021

Identifiers

DOI

10.1038/IJO.2008.55

1 reference

Dimensions Publication ID

18 August 2017

0 references

1 reference