Withaferin A: a proteasomal inhibitor promotes healing after injury and exerts anabolic effect on osteoporotic bone (Q37148287)

18 August 2017

Withaferin A: a proteasomal inhibitor promotes healing after injury and exerts anabolic effect on osteoporotic bone (English)

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18 August 2017

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V Khedgikar

1

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18 August 2017

P Kushwaha

2

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18 August 2017

J Gautam

3

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18 August 2017

A Verma

4

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18 August 2017

B Changkija

5

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18 August 2017

A Kumar

6

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18 August 2017

S Sharma

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18 August 2017

G K Nagar

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18 August 2017

D Singh

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18 August 2017

P K Trivedi

10

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18 August 2017

N S Sangwan

11

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18 August 2017

P R Mishra

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18 August 2017

R Trivedi

13

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18 August 2017

22 August 2013

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18 August 2017

Cell Death and Disease

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18 August 2017

4

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18 August 2017

e778

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https://scigraph.springernature.com/pub.10.1038/cddis.2013.294

18 August 2017

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Probing the anticancer mechanism of prospective herbal drug Withaferin A on mammals: a case study on human and bovine proteasomes

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6 September 2017

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6 September 2017

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6 September 2017

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Anabolics in osteoporosis: the emerging therapeutic tool.

6 September 2017

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6 September 2017

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6 September 2017

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The tumor proteasome is a primary target for the natural anticancer compound Withaferin A isolated from "Indian winter cherry".

6 September 2017

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Mechanisms of disease: is osteoporosis the obesity of bone?

6 September 2017

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Estrogen deficiency and bone loss: an inflammatory tale

6 September 2017

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Tumor necrosis factor promotes Runx2 degradation through up-regulation of Smurf1 and Smurf2 in osteoblasts.

6 September 2017

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The BMP signaling and in vivo bone formation

6 September 2017

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Bone morphogenetic proteins

6 September 2017

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Withaferin A is a potent inhibitor of angiogenesis

6 September 2017

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Expression of bone morphogenetic proteins, receptors, and tissue inhibitors in human fetal, adult, and osteoarthritic articular cartilage

6 September 2017

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Selective inhibitors of the osteoblast proteasome stimulate bone formation in vivo and in vitro

6 September 2017

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6 September 2017

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Regulatory mechanisms of osteoblast and osteoclast differentiation

6 September 2017

1 reference

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Transcriptional program of mouse osteoclast differentiation governed by the macrophage colony-stimulating factor and the ligand for the receptor activator of NFkappa B.

6 September 2017

1 reference

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Regulation of Smad degradation and activity by Smurf2, an E3 ubiquitin ligase

6 September 2017

1 reference

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Runx2 is a common target of transforming growth factor beta1 and bone morphogenetic protein 2, and cooperation between Runx2 and Smad5 induces osteoblast-specific gene expression in the pluripotent mesenchymal precursor cell line C2C12.

6 September 2017

1 reference

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Bone resorption by osteoclasts

6 September 2017

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Direct effects of 17 beta-estradiol on trabecular bone in ovariectomized rats

6 September 2017

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Lactacystin, a proteasome inhibitor, enhances BMP-induced osteoblastic differentiation by increasing active Smads

6 September 2017

1 reference

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Proteasome inhibition with bortezomib suppresses growth and induces apoptosis in osteosarcoma

14 September 2017

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Heparin inhibits osteoclastic differentiation and function

14 September 2017

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Bone morphogenetic protein-2 stimulates Runx2 acetylation

14 September 2017

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The effects of lovastatin on proteasome activities in highly purified rabbit 20 S proteasome preparations and mouse MC3T3-E1 osteoblastic cells

14 September 2017

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Increased expression of the receptor for activation of NF-κB and decreased runt-related transcription factor 2 expression in bone of rats with streptozotocin-induced diabetes

29 September 2017

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Bone loss and bone size after menopause

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3763455

Proinflammatory cytokines tumor necrosis factor-alpha and IL-6, but not IL-1, down-regulate the osteocalcin gene promoter

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3763455

Osteogenic efficacy enhancement of kaempferol through an engineered layer-by-layer matrix: a study in ovariectomized rats.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3763455

Discovery of coumarin-dihydropyridine hybrids as bone anabolic agents

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3763455

In vivo efficacy studies of layer-by-layer nano-matrix bearing kaempferol for the conditions of osteoporosis: a study in ovariectomized rat model.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3763455

Constituents of Dalbergia sissoo Roxb. leaves with osteogenic activity.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3763455

A novel quercetin analogue from a medicinal plant promotes peak bone mass achievement and bone healing after injury and exerts an anabolic effect on osteoporotic bone: the role of aryl hydrocarbon receptor as a mediator of osteogenic action.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3763455

Impaired bone healing pattern in mice with ovariectomy-induced osteoporosis: A drill-hole defect model.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3763455

A naturally occurring rare analog of quercetin promotes peak bone mass achievement and exerts anabolic effect on osteoporotic bone.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3763455

Deficiency of vitamin A delays bone healing process in association with reduced BMP2 expression after drill-hole injury in mice

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3763455

Medicarpin inhibits osteoclastogenesis and has nonestrogenic bone conserving effect in ovariectomized mice

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3763455

Identification of kaempferol-regulated proteins in rat calvarial osteoblasts during mineralization by proteomics

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3763455

Inhibition of NFkappaB by the natural product Withaferin A in cellular models of Cystic Fibrosis inflammation

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3763455

Effects of Egb 761 on bone mineral density, bone microstructure, and osteoblast function: Possible roles of quercetin and kaempferol

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3763455

Bone Loss and Bone Size after Menopause

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3763455

Expression of the osteoblast differentiation factor RUNX2 (Cbfa1/AML3/Pebp2alpha A) is inhibited by tumor necrosis factor-alpha

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3763455

Withdrawal of hormone replacement therapy is associated with significant vertebral bone loss in postmenopausal women

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3763455

Structures of withanosides I, II, III, IV, V, VI, and VII, new withanolide glycosides, from the roots of Indian Withania somnifera DUNAL. and inhibitory activity for tachyphylaxis to clonidine in isolated guinea-pig ileum

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3763455

Proteasome inhibitor and lymphocyte function: partial inhibition of cell-mediated cytotoxicity and implication that the lymphocyte proteasome may contain multiple chymotryptic domains

3 September 2018

1 reference

12 December 2020

A standardized phytopreparation from an Indian medicinal plant (Dalbergia sissoo) has antiresorptive and bone-forming effects on a postmenopausal osteoporosis model of rat

1 reference

12 December 2020

Quantification of Bone Microarchitecture with the Structure Model Index

1 reference

12 December 2020

The proteasome inhibitor bortezomib affects osteoblast differentiation in vitro and in vivo in multiple myeloma patients

1 reference

12 December 2020

Bisphosphonate (YM529) delays the repair of cortical bone defect after drill-hole injury by reducing terminal differentiation of osteoblasts in the mouse femur

1 reference

12 December 2020

Identifiers

DOI

10.1038/CDDIS.2013.294

1 reference

Dimensions Publication ID

18 August 2017

0 references

1 reference

18 August 2017

PubMed publication ID

23969857

1 reference