Transforming growth factor beta depletion is the primary determinant of Smad signaling kinetics (Q37156962)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19223462%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

title

Transforming growth factor beta depletion is the primary determinant of Smad signaling kinetics (English)

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21 January 2020

5

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21 January 2020

author name string

David C Clarke

1

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21 January 2020

Meredith L Brown

2

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21 January 2020

Richard A Erickson

3

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21 January 2020

Yigong Shi

4

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21 January 2020

language of work or name

English

0 references

publication date

17 February 2009

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Molecular and Cellular Biology

21 January 2020

published in

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21 January 2020

volume

29

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21 January 2020

issue

9

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21 January 2020

page(s)

2443-2455

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describes a project that uses

21 January 2020

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2668365/fullTextXML

inferred from PubMed Central ID database lookup

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GADD34-PP1c recruited by Smad7 dephosphorylates TGFbeta type I receptor

6 September 2017

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Self-enhanced ligand degradation underlies robustness of morphogen gradients.

6 September 2017

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Mechanisms of TGF-beta signaling from cell membrane to the nucleus

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6 September 2017

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Crystal structure of a phosphorylated Smad2. Recognition of phosphoserine by the MH2 domain and insights on Smad function in TGF-beta signaling

6 September 2017

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Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF beta receptor for degradation

6 September 2017

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6 September 2017

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6 September 2017

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Synergistic cooperation of TFE3 and smad proteins in TGF-beta-induced transcription of the plasminogen activator inhibitor-1 gene

6 September 2017

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14 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Demonstration that mutation of the type II transforming growth factor beta receptor inactivates its tumor suppressor activity in replication error-positive colon carcinoma cells

29 September 2017

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29 September 2017

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27 June 2018

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27 June 2018

1 reference

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27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2668365

Concomitant loss of transforming growth factor (TGF)-beta receptor types I and II in TGF-beta-resistant cell mutants implicates both receptor types in signal transduction.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2668365

Responses of embryonic Xenopus cells to activin and FGF are separated by multiple dose thresholds and correspond to distinct axes of the mesoderm.

27 June 2018

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27 June 2018

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A rate equation approach to elucidate the kinetics and robustness of the TGF-beta pathway

3 September 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2668365

Dual function of the Drosophila Alk1/Alk2 ortholog Saxophone shapes the Bmp activity gradient in the wing imaginal disc

3 September 2018

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Drosophila Dpp morphogen movement is independent of dynamin-mediated endocytosis but regulated by the glypican members of heparan sulfate proteoglycans.

3 September 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2668365

Analysis of Smad nucleocytoplasmic shuttling in living cells.

3 September 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2668365

Attenuation of the TGF-beta-Smad signaling pathway in pancreatic tumor cells confers resistance to TGF-beta-induced growth arrest.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2668365

Distinct endocytic pathways regulate TGF-β receptor signalling and turnover

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2668365

Do morphogen gradients arise by diffusion?

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2668365

A changing morphogen gradient is interpreted by continuous transduction flow.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2668365

The FYVE domain in Smad anchor for receptor activation (SARA) is sufficient for localization of SARA in early endosomes and regulates TGF-beta/Smad signalling

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2668365

Gradient formation of the TGF-beta homolog Dpp.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2668365

The interpretation of position in a morphogen gradient as revealed by occupancy of activin receptors

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2668365

An assay for transforming growth factor-beta using cells transfected with a plasminogen activator inhibitor-1 promoter-luciferase construct

3 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19223462

12 December 2020

inferred from PubMed ID database lookup

Characterization of a 60-kDa cell surface-associated transforming growth factor-beta binding protein that can interfere with transforming growth factor-beta receptor binding

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19223462

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1128/MCB.01443-08

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19223462%20AND%20SRC:MED&resulttype=core&format=json

release_bdvid5yakfbztf3ahk6fhtfwuy

21 January 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/bdvid5yakfbztf3ahk6fhtfwuy

24 November 2022

mapped directly with Wikidata item

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19223462%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19223462%20AND%20SRC:MED&resulttype=core&format=json