GGAP2/PIKE-a directly activates both the Akt and nuclear factor-kappaB pathways and promotes prostate cancer progression. (Q37158111)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19176382%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

title

GGAP2/PIKE-a directly activates both the Akt and nuclear factor-kappaB pathways and promotes prostate cancer progression (English)

1 reference

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20 January 2020

1 reference

6

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20 January 2020

author name string

Yi Cai

1

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20 January 2020

Jianghua Wang

2

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20 January 2020

Rile Li

3

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20 January 2020

Gustavo Ayala

4

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20 January 2020

Michael Ittmann

5

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20 January 2020

language of work or name

English

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publication date

27 January 2009

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20 January 2020

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20 January 2020

volume

69

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20 January 2020

issue

3

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20 January 2020

page(s)

819-827

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Clonogenic assay of cells in vitro.

20 January 2020

cites work

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PIKE-A is a proto-oncogene promoting cell growth, transformation and invasion

6 September 2017

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6 September 2017

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Phosphoinositol lipids bind to phosphatidylinositol 3 (PI3)-kinase enhancer GTPase and mediate its stimulatory effect on PI3-kinase and Akt signalings

6 September 2017

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Genetic alteration and expression of the phosphoinositol-3-kinase/Akt pathway genes PIK3CA and PIKE in human glioblastomas

6 September 2017

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PIKE (phosphatidylinositol 3-kinase enhancer)-A GTPase stimulates Akt activity and mediates cellular invasion

6 September 2017

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NF-kappaB activation in human prostate cancer: important mediator or epiphenomenon?

6 September 2017

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NF??B: A Pivotal Transcription Factor in Prostate Cancer Metastasis to Bone

6 September 2017

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PI3 kinase enhancer–Homer complex couples mGluRI to PI3 kinase, preventing neuronal apoptosis

6 September 2017

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GGAPs, a new family of bifunctional GTP-binding and GTPase-activating proteins

6 September 2017

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Interleukin-6 is an autocrine growth factor in human prostate cancer.

6 September 2017

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Interleukin-8 is a paracrine inducer of fibroblast growth factor 2, a stromal and epithelial growth factor in benign prostatic hyperplasia

6 September 2017

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Pike. A nuclear gtpase that enhances PI3kinase activity and is regulated by protein 4.1N

6 September 2017

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Modulation of hypoxia-inducible factor 1alpha expression by the epidermal growth factor/phosphatidylinositol 3-kinase/PTEN/AKT/FRAP pathway in human prostate cancer cells: implications for tumor angiogenesis and therapeutics

6 September 2017

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6 September 2017

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NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling

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6 September 2017

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Steroid receptor coactivator-3 and activator protein-1 coordinately regulate the transcription of components of the insulin-like growth factor/AKT signaling pathway

6 September 2017

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14 September 2017

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3 September 2018

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3 September 2018

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Myc-driven murine prostate cancer shares molecular features with human prostate tumors

3 September 2018

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Nuclear Factor- B Nuclear Localization Is Predictive of Biochemical Recurrence in Patients with Positive Margin Prostate Cancer

3 September 2018

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4 December 2018

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Homozygous deletion of the PTEN tumor suppressor gene in a subset of prostate adenocarcinomas

4 December 2018

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12 December 2020

Comparative genomic hybridization reveals DNA copy number gains to frequently occur in human prostate cancer

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12 December 2020

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12 December 2020

Inactivation of the PTEN tumor suppressor gene is associated with increased angiogenesis in clinically localized prostate carcinoma

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12 December 2020

10.1158/0008-5472.CAN-08-2537

Identifiers

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19176382%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

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20 January 2020

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