ASK1 and ASK2 differentially regulate the counteracting roles of apoptosis and inflammation in tumorigenesis. (Q37163034)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19214184%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

title

ASK1 and ASK2 differentially regulate the counteracting roles of apoptosis and inflammation in tumorigenesis (English)

1 reference

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21 January 2020

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2

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21 January 2020

Takuya Noguchi

8

1 reference

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21 January 2020

Hideki Nishitoh

10

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21 January 2020

Hidenori Ichijō

24

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21 January 2020

22

Yuji Taketani

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21 January 2020

15

Hitoshi Tsuda

1 reference

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21 January 2020

3

Hiromi Nakamura

1 reference

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21 January 2020

author name string

Takayuki Iriyama

1

1 reference

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21 January 2020

Yoshifumi Morimoto

4

1 reference

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21 January 2020

Takumi Kuroiwa

5

1 reference

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21 January 2020

Junya Mizukami

6

1 reference

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21 January 2020

Tsuyoshi Umeda

7

1 reference

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21 January 2020

Isao Naguro

9

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21 January 2020

Kaoru Saegusa

11

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21 January 2020

Kei Tobiume

12

1 reference

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21 January 2020

Toshiki Homma

13

1 reference

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21 January 2020

Yutaka Shimada

14

1 reference

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21 January 2020

Satoshi Aiko

16

1 reference

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21 January 2020

Issei Imoto

17

1 reference

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21 January 2020

Johji Inazawa

18

1 reference

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21 January 2020

Kazuhiro Chida

19

1 reference

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21 January 2020

Yoshimasa Kamei

20

1 reference

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21 January 2020

Shiro Kozuma

21

1 reference

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21 January 2020

Atsushi Matsuzawa

23

1 reference

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21 January 2020

language of work or name

English

0 references

publication date

12 February 2009

1 reference

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21 January 2020

1 reference

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21 January 2020

volume

28

1 reference

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21 January 2020

issue

7

1 reference

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21 January 2020

page(s)

843-853

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Oxidative stress in ulcerative colitis-associated carcinogenesis

21 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670860

Inflammation and lung cancer: roles of reactive oxygen/nitrogen species

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670860

Apoptosis signal-regulating kinase 1 in stress and immune response

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670860

Thioredoxin and TRAF family proteins regulate reactive oxygen species-dependent activation of ASK1 through reciprocal modulation of the N-terminal homophilic interaction of ASK1

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670860

Stress signaling in cancer.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670860

The pathways to tumor suppression via route p38.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670860

PRAK is essential for ras-induced senescence and tumor suppression

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670860

Apoptosis signal-regulating kinase (ASK) 2 functions as a mitogen-activated protein kinase kinase kinase in a heteromeric complex with ASK1

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670860

Targeting signal transduction as a strategy to treat inflammatory diseases.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670860

Inflammation in epithelial skin tumours: old stories and new ideas

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670860

Recruitment of tumor necrosis factor receptor-associated factor family proteins to apoptosis signal-regulating kinase 1 signalosome is essential for oxidative stress-induced cell death

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670860

Regulation of MAP kinase-dependent apoptotic pathway: implication of reactive oxygen and nitrogen species

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670860

Role of JNK activation in apoptosis: a double-edged sword

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670860

Activation and signaling of the p38 MAP kinase pathway

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670860

The basal layer in human squamous tumors harbors more UVA than UVB fingerprint mutations: a role for UVA in human skin carcinogenesis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670860

Mitogen-activated protein kinase activation in UV-induced signal transduction

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670860

6 September 2017

Inflammation and cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670860

ROS, stress-activated kinases and stress signaling in cancer

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670860

Activation of apoptosis signal-regulating kinase 1 by the stress-induced activating phosphorylation of pre-formed oligomer

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670860

Proliferation, cell cycle and apoptosis in cancer

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670860

Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670860

Activator protein 1 (AP-1)- and nuclear factor kappaB (NF-kappaB)-dependent transcriptional events in carcinogenesis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670860

Oxyradicals and DNA damage

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670860

Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670860

Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670860

Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670860

Oncogenic Ras-induced secretion of IL6 is required for tumorigenesis.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670860

ROS-dependent activation of the TRAF6-ASK1-p38 pathway is selectively required for TLR4-mediated innate immunity.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670860

Essential role of tumor necrosis factor alpha (TNF-alpha) in tumor promotion as revealed by TNF-alpha-deficient mice.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670860

Inhibition of the TPA-induced cutaneous inflammation and hyperplasia by EC-SOD.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670860

Suppression of skin tumorigenesis in c-Jun NH(2)-terminal kinase-2-deficient mice.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670860

7,12-dimethylbenz[a]anthracene induces oxidative DNA modification in vivo.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670860

p38alpha MAP kinase as a sensor of reactive oxygen species in tumorigenesis.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670860

Ultraviolet A induces apoptosis via reactive oxygen species in a model for Smith-Lemli-Opitz syndrome

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670860

Mice deficient in tumor necrosis factor-alpha are resistant to skin carcinogenesis.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670860

ASK1 is required for sustained activations of JNK/p38 MAP kinases and apoptosis

3 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FEMBOJ.2009.32

p38α suppresses normal and cancer cell proliferation by antagonizing the JNK–c-Jun pathway

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FEMBOJ.2009.32

Suppression of tumor promoter-induced oxidative stress and inflammatory responses in mouse skin by a superoxide generation inhibitor 1'-acetoxychavicol acetate

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19214184

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Prior exposure to restraint stress enhances 7,12-dimethylbenz(a)anthracene (DMBA) induced DNA damage in rats

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19214184

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

p38α MAP kinase is essential in lung stem and progenitor cell proliferation and differentiation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19214184

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/EMBOJ.2009.32

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19214184%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19214184%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

1 reference