Rare MTNR1B variants impairing melatonin receptor 1B function contribute to type 2 diabetes (Q37173576)

18 August 2017

Rare MTNR1B variants impairing melatonin receptor 1B function contribute to type 2 diabetes (English)

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18 August 2017

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28

Philippe Froguel

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Inês Barroso

26

Inês Barroso

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Claudia Langenberg

16

Claudia Langenberg

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Loic Yengo

4

Loïc Yengo

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Katherine Fawcett

Katherine Fawcett

3

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Robert Sladek

Robert Sladek

23

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Amélie Bonnefond

Amélie Bonnefond

1

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Michel Marre

Michel Marre

14

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Serge Hercberg

Serge Hercberg

11

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Sébastien Czernichow

10

Sébastien Czernichow

1 reference

18 August 2017

Mark I McCarthy

24

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Nicholas J. Wareham

22

Nicholas J Wareham

1 reference

18 August 2017

Nathalie Clément

2

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18 August 2017

Emmanuel Vaillant

5

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Jean-Luc Guillaume

6

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18 August 2017

Aurélie Dechaume

7

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18 August 2017

Ronan Roussel

9

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18 August 2017

Samy Hadjadj

12

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Beverley Balkau

13

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18 August 2017

Olivier Lantieri

15

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18 August 2017

Meta-Analysis of Glucose and Insulin-Related Traits Consortium (MAGIC)

18

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18 August 2017

Guillaume Charpentier

19

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18 August 2017

Martine Vaxillaire

20

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18 August 2017

Ghislain Rocheleau

21

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18 August 2017

Christian Dina

25

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Ralf Jockers

27

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18 August 2017

language of work or name

English

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publication date

29 January 2012

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44

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3

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297-301

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https://scigraph.springernature.com/pub.10.1038/ng.1053

18 August 2017

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cites work

Circadian integration of metabolism and energetics

1 reference

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New evidence for a role of melatonin in glucose regulation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3773908

A novel adaptive method for the analysis of next-generation sequencing data to detect complex trait associations with rare variants due to gene main effects and interactions

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3773908

Reduced expression of IFIH1 is protective for type 1 diabetes

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3773908

Excess of rare variants in genes identified by genome-wide association study of hypertriglyceridemia

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3773908

International Union of Basic and Clinical Pharmacology. LXXV. Nomenclature, classification, and pharmacology of G protein-coupled melatonin receptors

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3773908

Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3773908

Disruption of the clock components CLOCK and BMAL1 leads to hypoinsulinaemia and diabetes

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3773908

A method and server for predicting damaging missense mutations

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3773908

MTNR1B G24E variant associates With BMI and fasting plasma glucose in the general population in studies of 22,142 Europeans

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3773908

Finding the missing heritability of complex diseases

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3773908

Agomelatine, a melatonin agonist with antidepressant properties

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3773908

Common vs. rare allele hypotheses for complex diseases

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3773908

Ligand binding and micro-switches in 7TM receptor structures

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3773908

Rare variants of IFIH1, a gene implicated in antiviral responses, protect against type 1 diabetes

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3773908

A variant near MTNR1B is associated with increased fasting plasma glucose levels and type 2 diabetes risk

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3773908

Common variant in MTNR1B associated with increased risk of type 2 diabetes and impaired early insulin secretion

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3773908

Variants in MTNR1B influence fasting glucose levels

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3773908

Prognostic value of the insertion/deletion polymorphism of the ACE gene in type 2 diabetic subjects: results from the Non-insulin-dependent Diabetes, Hypertension, Microalbuminuria or Proteinuria, Cardiovascular Events, and Ramipril (DIABHYCAR), Dia

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3773908

Melatonin receptors, heterodimerization, signal transduction and binding sites: what's new?

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3773908

A genome-wide association study identifies novel risk loci for type 2 diabetes

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3773908

Cohort profile: the Hertfordshire cohort study.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3773908

A genome-wide scan for childhood obesity-associated traits in French families shows significant linkage on chromosome 6q22.31-q23.2.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3773908

Monitoring of ligand-independent dimerization and ligand-induced conformational changes of melatonin receptors in living cells by bioluminescence resonance energy transfer

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3773908

A primary prevention trial using nutritional doses of antioxidant vitamins and minerals in cardiovascular diseases and cancers in a general population: the SU.VI.MAX study--design, methods, and participant characteristics. SUpplementation en VItamin

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3773908

Deep resequencing reveals excess rare recent variants consistent with explosive population growth

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3773908

Standards of medical care in diabetes--2008.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3773908

[An epidemiologic survey from a network of French Health Examination Centres, (D.E.S.I.R.): epidemiologic data on the insulin resistance syndrome]

3 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22286214

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Undiagnosed glucose intolerance in the community: the Isle of Ely Diabetes Project

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22286214

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NG.1053

1 reference

Dimensions Publication ID

18 August 2017

0 references

1 reference

18 August 2017

1 reference