Cyclooxygenase-1 inhibition reduces amyloid pathology and improves memory deficits in a mouse model of Alzheimer's disease. (Q37190465)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23083210%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

title

Cyclooxygenase-1 inhibition reduces amyloid pathology and improves memory deficits in a mouse model of Alzheimer's disease (English)

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15 February 2020

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0 references

1 reference

ChEBI release 2020-05-28

2

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15 February 2020

Raymond Turner

7

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15 February 2020

8

Mark P Mattson

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15 February 2020

author name string

Sang-Ho Choi

1

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15 February 2020

Luca Caracciolo

3

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15 February 2020

S Sakura Minami

4

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15 February 2020

Takako Niikura

5

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15 February 2020

Yasuji Matsuoka

6

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15 February 2020

Francesca Bosetti

9

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15 February 2020

language of work or name

English

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publication date

21 November 2012

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Journal of Neurochemistry

15 February 2020

published in

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15 February 2020

volume

124

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15 February 2020

issue

1

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15 February 2020

page(s)

59-68

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ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse models

15 February 2020

cites work

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6 September 2017

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6 September 2017

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Modulation of nuclear factor-kappa B activity by indomethacin influences A beta levels but not A beta precursor protein metabolism in a model of Alzheimer's disease

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6 September 2017

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14 September 2017

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26 June 2018

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26 June 2018

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26 June 2018

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Identification of Fc gamma RI, II and III on normal human brain ramified microglia and on microglia in senile plaques in Alzheimer's disease

26 June 2018

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Reactive microglia in patients with senile dementia of the Alzheimer type are positive for the histocompatibility glycoprotein HLA-DR.

26 June 2018

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Ultrastructural studies of the cells forming amyloid in the cortical vessel wall in Alzheimer's disease

26 June 2018

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Cyclooxygenase (COX)-1 activity precedes the COX-2 induction in Aβ-induced neuroinflammation

26 June 2018

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Triflusal reduces dense-core plaque load, associated axonal alterations and inflammatory changes, and rescues cognition in a transgenic mouse model of Alzheimer's disease.

3 September 2018

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Blocking Abeta42 accumulation delays the onset and progression of tau pathology via the C terminus of heat shock protein70-interacting protein: a mechanistic link between Abeta and tau pathology.

3 September 2018

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3 September 2018

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Cyclooxygenase-2 inhibition improves amyloid-beta-mediated suppression of memory and synaptic plasticity

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3780364

Quantification of cerebral amyloid angiopathy and parenchymal amyloid plaques with Congo red histochemical stain.

3 September 2018

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Reduction of soluble Abeta and tau, but not soluble Abeta alone, ameliorates cognitive decline in transgenic mice with plaques and tangles

3 September 2018

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Temporal profile of amyloid-beta (Abeta) oligomerization in an in vivo model of Alzheimer disease. A link between Abeta and tau pathology

3 September 2018

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Deletion of the prostaglandin E2 EP2 receptor reduces oxidative damage and amyloid burden in a model of Alzheimer's disease.

3 September 2018

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Microglial phagocytosis induced by fibrillar beta-amyloid and IgGs are differentially regulated by proinflammatory cytokines.

3 September 2018

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Acute treatment with the PPARgamma agonist pioglitazone and ibuprofen reduces glial inflammation and Abeta1-42 levels in APPV717I transgenic mice

3 September 2018

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The role of cyclo-oxygenase 1 and 2 activity in prostaglandin E(2) secretion by cultured human adult microglia: implications for Alzheimer's disease

3 September 2018

1 reference

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Microglial activation and beta -amyloid deposit reduction caused by a nitric oxide-releasing nonsteroidal anti-inflammatory drug in amyloid precursor protein plus presenilin-1 transgenic mice.

3 September 2018

1 reference

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Activation of the JNK/p38 pathway occurs in diseases characterized by tau protein pathology and is related to tau phosphorylation but not to apoptosis.

3 September 2018

1 reference

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Ibuprofen effects on Alzheimer pathology and open field activity in APPsw transgenic mice

3 September 2018

1 reference

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Cyclooxygenase expression in microglia and neurons in Alzheimer's disease and control brain.

3 September 2018

1 reference

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Cyclooxygenase-1 in human Alzheimer and control brain: quantitative analysis of expression by microglia and CA3 hippocampal neurons.

3 September 2018

1 reference

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Monoclonal antibody AT8 recognises tau protein phosphorylated at both serine 202 and threonine 205.

3 September 2018

1 reference

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Altered neuronal and microglial responses to excitotoxic and ischemic brain injury in mice lacking TNF receptors

3 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23083210

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1111/JNC.12059

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23083210%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23083210%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23083210%20AND%20SRC:MED&resulttype=core&format=json