PIK3CA mutations in human solid tumors: role in sensitivity to various therapeutic approaches (Q37192606)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19305151%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

review article

1 reference

title

PIK3CA mutations in human solid tumors: role in sensitivity to various therapeutic approaches (English)

1 reference

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24 January 2020

2

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24 January 2020

Ferdinando Nicoletti

6

1 reference

ORCID Public Data File 2021

Linda S Steelman

3

object named as

Linda S Steelman

1 reference

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24 January 2020

8

James A McCubrey

1 reference

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24 January 2020

9

Massimo Libra

1 reference

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24 January 2020

7

Franca Stivala

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24 January 2020

author name string

Giovanni Ligresti

1

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24 January 2020

Andrea Cavallaro

4

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24 January 2020

Francesco Basile

5

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24 January 2020

publication date

23 May 2009

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24 January 2020

number of pages

7

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based on heuristic

inferred from page(s)

published in

Cell Cycle

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24 January 2020

volume

8

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24 January 2020

issue

9

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24 January 2020

page(s)

1352-1358

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19305151%20AND%20SRC:MED&resulttype=core&format=json

PIK3CA-activating mutations and chemotherapy sensitivity in stage II-III breast cancer

24 January 2020

cites work

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PIK3CA, KRAS, and BRAF mutations in intraductal papillary mucinous neoplasm/carcinoma (IPMN/C) of the pancreas.

6 September 2017

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PIK3CA mutation/PTEN expression status predicts response of colon cancer cells to the epidermal growth factor receptor inhibitor cetuximab

6 September 2017

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The structure of a human p110alpha/p85alpha complex elucidates the effects of oncogenic PI3Kalpha mutations

6 September 2017

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A functional genetic approach identifies the PI3K pathway as a major determinant of trastuzumab resistance in breast cancer

6 September 2017

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Mechanism of two classes of cancer mutations in the phosphoinositide 3-kinase catalytic subunit

6 September 2017

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6 September 2017

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New functions for PI3K in the control of cell division.

6 September 2017

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Regulation of PTEN function as a PIP3 gatekeeper through membrane interaction

6 September 2017

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Akt/PKB signaling in cancer: a function in cell motility and invasion

6 September 2017

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Cancer-specific mutations in PIK3CA are oncogenic in vivo

6 September 2017

1 reference

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PIK3CA mutations correlate with hormone receptors, node metastasis, and ERBB2, and are mutually exclusive with PTEN loss in human breast carcinoma

6 September 2017

1 reference

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Phosphatidylinositol 3-kinase mutations identified in human cancer are oncogenic

6 September 2017

1 reference

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PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients.

6 September 2017

1 reference

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PTEN function: how normal cells control it and tumour cells lose it

6 September 2017

1 reference

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High frequency of mutations of the PIK3CA gene in human cancers

6 September 2017

1 reference

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6 September 2017

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Roles of the PI-3K and MEK pathways in Ras-mediated chemoresistance in breast cancer cells.

6 September 2017

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PKB binding proteins. Getting in on the Akt.

6 September 2017

1 reference

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The phosphoinositide 3-kinase pathway

6 September 2017

1 reference

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Efficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancer

6 September 2017

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PTEN: life as a tumor suppressor

6 September 2017

1 reference

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A role of the kinase mTOR in cellular transformation induced by the oncoproteins P3k and Akt.

6 September 2017

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Signaling by distinct classes of phosphoinositide 3-kinases

6 September 2017

1 reference

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Ribosomal S6 kinase signaling and the control of translation

6 September 2017

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Regulation of the p85/p110alpha phosphatidylinositol 3'-kinase. Distinct roles for the n-terminal and c-terminal SH2 domains

6 September 2017

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The interaction of small domains between the subunits of phosphatidylinositol 3-kinase determines enzyme activity

6 September 2017

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PIK3CA mutation is an oncogenic aberration at advanced stages of oral squamous cell carcinoma

6 September 2017

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PIK3CA mutations in head and neck squamous cell carcinoma

14 September 2017

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High frequency of coexistent mutations of PIK3CA and PTEN genes in endometrial carcinoma

14 September 2017

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Mutant PIK3CA promotes cell growth and invasion of human cancer cells

14 September 2017

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14 September 2017

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PI 3-kinase: structural and functional analysis of intersubunit interactions

28 September 2017

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The mRNA 5' cap-binding protein eIF4E and control of cell growth

28 September 2017

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Frequent mutation of the PIK3CA gene in ovarian and breast cancers.

26 June 2018

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HER2/PI-3K/Akt activation leads to a multidrug resistance in human breast adenocarcinoma cells.

3 September 2018

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Overexpression of Akt/AKT can modulate chemotherapy-induced apoptosis.

3 September 2018

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Mutations of PIK3CA in Anaplastic Oligodendrogliomas, High-Grade Astrocytomas, and Medulloblastomas

3 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.4161%2FCC.8.9.8255

Direct targets of phosphoinositide 3-kinase products in membrane traffic and signal transduction

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19305151

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Mutation of the PIK3CA gene in ovarian and breast cancer

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19305151

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.4161/CC.8.9.8255

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19305151%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19305151%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

1 reference