Molecular mechanism of hepatic stellate cell activation and antifibrotic therapeutic strategies. (Q37207064)

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10 January 2020

review article

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title

Molecular mechanism of hepatic stellate cell activation and antifibrotic therapeutic strategies (English)

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10 January 2020

1

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10 January 2020

author name string

Zhang-Xiu Liao

2

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10 January 2020

Jie Ping

3

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10 January 2020

Dan Xu

4

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10 January 2020

Hui Wang

5

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10 January 2020

publication date

4 July 2008

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Journal of Gastroenterology

10 January 2020

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18600385%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

volume

43

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10 January 2020

issue

6

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10 January 2020

page(s)

419-428

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10 January 2020

1 reference

https://api.crossref.org/works/10.1007%2FS00535-008-2180-Y

Posttranscriptional regulation of collagen alpha1(I) mRNA in hepatic stellate cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-008-2180-Y

Leptin stimulates alpha1(I) collagen expression in human hepatic stellate cells via the phosphatidylinositol 3-kinase/Akt signalling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-008-2180-Y

The future of GI and liver research: editorial perspectives. III. JNK/AP-1 regulation of hepatocyte death

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-008-2180-Y

Activation of peroxisome proliferator-activated receptor-gamma contributes to the inhibitory effects of curcumin on rat hepatic stellate cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-008-2180-Y

Growth inhibition and apoptosis in liver myofibroblasts promoted by hepatocyte growth factor leads to resolution from liver cirrhosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-008-2180-Y

Prevention of rat hepatic fibrosis by the protease inhibitor, camostat mesilate, via reduced generation of active TGF-beta

21 January 2018

1 reference

12 December 2020

Targeted inhibition of the KLF6 splice variant, KLF6 SV1, suppresses prostate cancer cell growth and spread.

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Therapeutic efficacy of an angiotensin II receptor antagonist in patients with nonalcoholic steatohepatitis

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Stimulation of hepatic lipocyte collagen production by Kupffer cell-derived transforming growth factor beta: implication for a pathogenetic role in alcoholic liver fibrogenesis

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The bone marrow functionally contributes to liver fibrosis.

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12 December 2020

Urokinase-type plasminogen activator gene therapy in liver cirrhosis is mediated by collagens gene expression down-regulation and up-regulation of MMPs, HGF and VEGF.

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SMAD and p38 MAPK signaling pathways independently regulate alpha1(I) collagen gene expression in unstimulated and transforming growth factor-beta-stimulated hepatic stellate cells.

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Regulation of endothelin-1 synthesis by endothelin-converting enzyme-1 during wound healing

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Enhanced interstitial collagenase (matrix metalloproteinase-13) production of Kupffer cell by gadolinium chloride prevents pig serum-induced rat liver fibrosis

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The DNA binding protein BTEB mediates acetaldehyde-induced, jun N-terminal kinase-dependent alphaI(I) collagen gene expression in rat hepatic stellate cells

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Mechanisms of spontaneous resolution of rat liver fibrosis. Hepatic stellate cell apoptosis and reduced hepatic expression of metalloproteinase inhibitors

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Kupffer cell–derived 95-kd type IV collagenase/gelatinase B: Characterization and expression in cultured cells

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12 December 2020

Wnt antagonism inhibits hepatic stellate cell activation and liver fibrosis

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Cytokines and cellular crosstalk involved in the activation of fat-storing cells

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Toll-like receptor 4 mediates inflammatory signaling by bacterial lipopolysaccharide in human hepatic stellate cells

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Scar-associated macrophages are a major source of hepatic matrix metalloproteinase-13 and facilitate the resolution of murine hepatic fibrosis

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Successful Targeting to Rat Hepatic Stellate Cells Using Albumin Modified with Cyclic Peptides That Recognize the Collagen Type VI Receptor

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TAK1/JNK and p38 have opposite effects on rat hepatic stellate cells

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12 December 2020

Cirrhotic rat livers with extensive fibrosis can be safely transduced with clinical-grade adenoviral vectors. Evidence of cirrhosis reversion

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12 December 2020

Inhibition of transforming growth factor beta prevents progression of liver fibrosis and enhances hepatocyte regeneration in dimethylnitrosamine-treated rats

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A Germline DNA Polymorphism Enhances Alternative Splicing of theKLF6Tumor Suppressor Gene and Is Associated with Increased Prostate Cancer Risk

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Discoidin domain receptor 2 interacts with Src and Shc following its activation by type I collagen

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Cooperation of liver cells in health and disease

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12 December 2020

Antifibrotic effects of a tissue inhibitor of metalloproteinase-1 antibody on established liver fibrosis in rats

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12 December 2020

Neutrophil-derived superoxide anion induces lipid peroxidation and stimulates collagen synthesis in human hepatic stellate cells: role of nitric oxide

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Bone marrow-derived stem cells and "plasticity".

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Fibrogenesis II. Metalloproteinases and their inhibitors in liver fibrosis

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12 December 2020

How can transforming growth factor beta be targeted usefully to combat liver fibrosis?

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12 December 2020

Proteasome inhibition induces hepatic stellate cell apoptosis

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12 December 2020

Increased expression of monocyte chemotactic protein-1 during active hepatic fibrogenesis: correlation with monocyte infiltration.

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12 December 2020

Krüppel-like factors: three fingers in many pies

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12 December 2020

Gliotoxin stimulates the apoptosis of human and rat hepatic stellate cells and enhances the resolution of liver fibrosis in rats

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12 December 2020

Apoptotic body engulfment by a human stellate cell line is profibrogenic.

1 reference

12 December 2020

Pentoxifylline downregulates alpha (I) collagen expression by the inhibition of Ikappabalpha degradation in liver stellate cells

1 reference

12 December 2020

Molecular regulation of hepatic fibrogenesis

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12 December 2020

Sp1 binding activity increases in activated Ito cells

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12 December 2020

Stimulation and proliferation of primary rat hepatic stellate cells by cytochrome P450 2E1-derived reactive oxygen species

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12 December 2020

In pursuit of the "Holy Grail"--stem cells, hepatic injury, fibrogenesis and repair

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12 December 2020

Upstream tissue inhibitor of metalloproteinases-1 (TIMP-1) element-1, a novel and essential regulatory DNA motif in the human TIMP-1 gene promoter, directly interacts with a 30-kDa nuclear protein.

1 reference

12 December 2020

Synergism between hepatocytes and Kupffer cells in the activation of fat storing cells (perisinusoidal lipocytes)

1 reference

12 December 2020

The role of focal adhesion kinase-phosphatidylinositol 3-kinase-akt signaling in hepatic stellate cell proliferation and type I collagen expression

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12 December 2020

Inhibition of inhibitor of kappaB kinases stimulates hepatic stellate cell apoptosis and accelerated recovery from rat liver fibrosis.

1 reference

12 December 2020

Rat hepatic stellate cells become retinoid unresponsive during activation

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12 December 2020

Gliotoxin causes apoptosis and necrosis of rat Kupffer cells in vitro and in vivo in the absence of oxidative stress: exacerbation by caspase and serine protease inhibition

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12 December 2020

Immunomodulation of activated hepatic stellate cells by mesenchymal stem cells

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12 December 2020

Attenuated liver fibrosis in the absence of B cells

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12 December 2020

Loss of MMP 13 attenuates murine hepatic injury and fibrosis during cholestasis

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12 December 2020

Regulation of alpha1(I) collagen messenger RNA decay by interactions with alphaCP at the 3'-untranslated region

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12 December 2020

Cytokine receptors and signaling in hepatic stellate cells

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12 December 2020

Leptin in the field of hepatic fibrosis: a pivotal or an incidental player?

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12 December 2020

Endothelin-1 promotes myofibroblast induction through the ETA receptor via a rac/phosphoinositide 3-kinase/Akt-dependent pathway and is essential for the enhanced contractile phenotype of fibrotic fibroblasts.

1 reference

12 December 2020

Peroxisome proliferator-activated receptor gamma induces a phenotypic switch from activated to quiescent hepatic stellate cells

1 reference

12 December 2020

Apoptosis of hepatic stellate cells: involvement in resolution of biliary fibrosis and regulation by soluble growth factors

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12 December 2020

Cell-specific expression of transforming growth factor-beta in rat liver. Evidence for autocrine regulation of hepatocyte proliferation

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12 December 2020

The role and regulation of hepatic stellate cell apoptosis in reversal of liver fibrosis

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12 December 2020

Pattern recognition receptors: a contemporary view on liver diseases.

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12 December 2020

Antisense strategy against PDGF B-chain proves effective in preventing experimental liver fibrogenesis

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12 December 2020

Strain-specific differences in mouse hepatic wound healing are mediated by divergent T helper cytokine responses

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12 December 2020

DDR2 receptor promotes MMP-2-mediated proliferation and invasion by hepatic stellate cells

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12 December 2020

Expression of Smads during in vitro transdifferentiation of hepatic stellate cells to myofibroblasts

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12 December 2020

An oral endothelin-A receptor antagonist blocks collagen synthesis and deposition in advanced rat liver fibrosis

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12 December 2020

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Human chemokines: an update

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Collagenases and liver fibrosis

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12 December 2020

The cellular pathogenesis of portal hypertension: stellate cell contractility, endothelin, and nitric oxide

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Molecular regulation of hepatic fibrosis, an integrated cellular response to tissue injury

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12 December 2020

The cell biology of liver fibrogenesis - an imbalance of proliferation, growth arrest and apoptosis of myofibroblasts

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12 December 2020

Selective targeting of pentoxifylline to hepatic stellate cells using a novel platinum-based linker technology.

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12 December 2020

Transplantation of bone marrow cells reduces CCl4-induced liver fibrosis in mice

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12 December 2020

Imatinib mesylate (STI-571) attenuates liver fibrosis development in rats.

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12 December 2020

DLPC decreases TGF-beta1-induced collagen mRNA by inhibiting p38 MAPK in hepatic stellate cells

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12 December 2020

Cultured human liver fat-storing cells produce monocyte chemotactic protein-1. Regulation by proinflammatory cytokines.

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12 December 2020

Peroxisome proliferator-activated receptors and hepatic stellate cell activation

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JunD regulates transcription of the tissue inhibitor of metalloproteinases-1 and interleukin-6 genes in activated hepatic stellate cells

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12 December 2020

Inhibition of apoptosis of activated hepatic stellate cells by tissue inhibitor of metalloproteinase-1 is mediated via effects on matrix metalloproteinase inhibition: implications for reversibility of liver fibrosis

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12 December 2020

Rat hepatic stellate cells produce cytokine-induced neutrophil chemoattractant in culture and in vivo

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Fibrotic disease and the T(H)1/T(H)2 paradigm

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Effect of IL-4 and IL-13 on collagen production in cultured LI90 human hepatic stellate cells

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12 December 2020

Systemic infusion of FLK1(+) mesenchymal stem cells ameliorate carbon tetrachloride-induced liver fibrosis in mice

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12 December 2020

NF-kappaB inhibits expression of the alpha1(I) collagen gene.

1 reference

12 December 2020