Multiple P-TEFbs cooperatively regulate the release of promoter-proximally paused RNA polymerase II. (Q37211018)

19 August 2017

Multiple P-TEFbs cooperatively regulate the release of promoter-proximally paused RNA polymerase II. (English)

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19 August 2017

3

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9 June 2020

Min Liu

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9 June 2020

author name string

Xiaodong Lu

1

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9 June 2020

Xinxing Zhu

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9 June 2020

Bin Yu

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9 June 2020

Yu Wang

6

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9 June 2020

Muhua Rao

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Haiyang Yang

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9 June 2020

Kai Zhou

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9 June 2020

Yao Wang

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9 June 2020

Yanheng Chen

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9 June 2020

Meihua Chen

12

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9 June 2020

Songkuan Zhuang

13

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9 June 2020

Lin-Feng Chen

14

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9 June 2020

Runzhong Liu

15

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9 June 2020

Ruichuan Chen

16

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9 June 2020

language of work or name

English

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publication date

28 June 2016

1 reference

19 August 2017

15

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inferred from page(s)

published in

Nucleic Acids Research

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9 June 2020

volume

44

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9 June 2020

issue

14

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9 June 2020

page(s)

6853-6867

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Creative Commons Attribution-NonCommercial 4.0 International

9 June 2020

copyright license

start time

11 November 2016

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

Ready, pause, go: regulation of RNA polymerase II pausing and release by cellular signaling pathways

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BRD4 associates with p53 in DNMT3A-mutated leukemia cells and is implicated in apoptosis by the bromodomain inhibitor JQ1.

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Mediator MED23 regulates basal transcription in vivo via an interaction with P-TEFb

6 September 2017

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Transcription elongation factors DSIF and NELF: promoter-proximal pausing and beyond

6 September 2017

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Investigation of receptor interacting protein (RIP3)-dependent protein phosphorylation by quantitative phosphoproteomics

6 September 2017

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The super elongation complex (SEC) family in transcriptional control

6 September 2017

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RNA polymerase II elongation control

6 September 2017

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Signal-induced Brd4 release from chromatin is essential for its role transition from chromatin targeting to transcriptional regulation.

6 September 2017

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Human Polymerase-Associated Factor complex (PAFc) connects the Super Elongation Complex (SEC) to RNA polymerase II on chromatin

6 September 2017

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Human mediator subunit MED26 functions as a docking site for transcription elongation factors

6 September 2017

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Reprogramming transcription by distinct classes of enhancers functionally defined by eRNA

6 September 2017

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Pausing of RNA polymerase II disrupts DNA-specified nucleosome organization to enable precise gene regulation

6 September 2017

1 reference

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Selective inhibition of BET bromodomains

6 September 2017

1 reference

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Interactions between DSIF (DRB sensitivity inducing factor), NELF (negative elongation factor), and the Drosophila RNA polymerase II transcription elongation complex

6 September 2017

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Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities

6 September 2017

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HIV-1 Tat and host AFF4 recruit two transcription elongation factors into a bifunctional complex for coordinated activation of HIV-1 transcription

6 September 2017

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c-Myc regulates transcriptional pause release

6 September 2017

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CDK8 is a positive regulator of transcriptional elongation within the serum response network

6 September 2017

1 reference

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Global analysis of short RNAs reveals widespread promoter-proximal stalling and arrest of Pol II in Drosophila

6 September 2017

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A capping-independent function of MePCE in stabilizing 7SK snRNA and facilitating the assembly of 7SK snRNP.

6 September 2017

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Histone crosstalk between H3S10ph and H4K16ac generates a histone code that mediates transcription elongation

6 September 2017

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Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

6 September 2017

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Brd4 coactivates transcriptional activation of NF-kappaB via specific binding to acetylated RelA

6 September 2017

1 reference

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Nascent RNA sequencing reveals widespread pausing and divergent initiation at human promoters

6 September 2017

1 reference

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PP2B and PP1alpha cooperatively disrupt 7SK snRNP to release P-TEFb for transcription in response to Ca2+ signaling

6 September 2017

1 reference

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RNA polymerase is poised for activation across the genome

6 September 2017

1 reference

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RNA polymerase stalling at developmental control genes in the Drosophila melanogaster embryo

6 September 2017

1 reference

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Conserved P-TEFb-interacting domain of BRD4 inhibits HIV transcription

6 September 2017

1 reference

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A chromatin landmark and transcription initiation at most promoters in human cells

6 September 2017

1 reference

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Quantitative proteomic analysis of distinct mammalian Mediator complexes using normalized spectral abundance factors

6 September 2017

1 reference

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Controlling the elongation phase of transcription with P-TEFb

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5001612

Transcriptional pausing caused by NELF plays a dual role in regulating immediate-early expression of the junB gene

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5001612

Gene-specific requirement for P-TEFb activity and RNA polymerase II phosphorylation within the p53 transcriptional program

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5001612

Recruitment of P-TEFb for stimulation of transcriptional elongation by the bromodomain protein Brd4

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5001612

The bromodomain protein Brd4 is a positive regulatory component of P-TEFb and stimulates RNA polymerase II-dependent transcription

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5001612

Phosphorylation of serine 2 within the RNA polymerase II C-terminal domain couples transcription and 3' end processing

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5001612

Dynamics of human immunodeficiency virus transcription: P-TEFb phosphorylates RD and dissociates negative effectors from the transactivation response element

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5001612

Inhibition of P-TEFb (CDK9/Cyclin T) kinase and RNA polymerase II transcription by the coordinated actions of HEXIM1 and 7SK snRNA

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5001612

Human transcription elongation factor NELF: identification of novel subunits and reconstitution of the functionally active complex

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5001612

Evidence that negative elongation factor represses transcription elongation through binding to a DRB sensitivity-inducing factor/RNA polymerase II complex and RNA.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5001612

Stimulatory effect of splicing factors on transcriptional elongation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5001612

Transcription elongation takes central stage: the P-TEFb connection.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5001612

P-TEFb-mediated phosphorylation of hSpt5 C-terminal repeats is critical for processive transcription elongation

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5001612

Phosphorylated positive transcription elongation factor b (P-TEFb) is tagged for inhibition through association with 7SK snRNA.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5001612

Isolation and functional characterization of P-TEFb-associated factors that control general and HIV-1 transcriptional elongation

3 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27353326

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12 December 2020

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Identifiers

DOI

10.1093/NAR/GKW571

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27353326%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27353326%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

PubMed publication ID

27353326

1 reference