Impaired development of human Th1 cells in patients with deficient expression of STAT4. (Q37237461)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19359411%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

title

Impaired development of human Th1 cells in patients with deficient expression of STAT4 (English)

1 reference

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25 January 2020

3

1 reference

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25 January 2020

Mark H. Kaplan

7

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25 January 2020

author name string

Hua-Chen Chang

1

1 reference

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25 January 2020

Ling Han

2

1 reference

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25 January 2020

Evelyn T Nguyen

4

1 reference

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25 January 2020

David Pelloso

5

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25 January 2020

Michael J Robertson

6

1 reference

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25 January 2020

language of work or name

English

0 references

publication date

9 April 2009

1 reference

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25 January 2020

1 reference

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25 January 2020

volume

113

1 reference

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25 January 2020

issue

23

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25 January 2020

page(s)

5887-5890

1 reference

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Signal transducer and activator of transcription 4 is required for the transcription factor T-bet to promote T helper 1 cell-fate determination

25 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700324

STAT4 isoforms differentially regulate Th1 cytokine production and the severity of inflammatory bowel disease

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700324

An insight into molecular mechanisms of human T helper cell differentiation

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700324

Genetic background and the dilemma of translating mouse studies to humans

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700324

STAT4: a critical regulator of inflammation in vivo

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700324

STAT4 requires the N-terminal domain for efficient phosphorylation

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700324

Interleukin 12 immunotherapy after autologous stem cell transplantation for hematological malignancies.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700324

STAT4 serine phosphorylation is critical for IL-12-induced IFN-gamma production but not for cell proliferation

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700324

Residual type 1 immunity in patients genetically deficient for interleukin 12 receptor beta1 (IL-12Rbeta1): evidence for an IL-12Rbeta1-independent pathway of IL-12 responsiveness in human T cells

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700324

A novel transcription factor, T-bet, directs Th1 lineage commitment

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700324

Selective expression of an interleukin-12 receptor component by human T helper 1 cells

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700324

A functional interleukin 12 receptor complex is composed of two beta-type cytokine receptor subunits

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700324

Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700324

Interleukin 12 signaling in T helper type 1 (Th1) cells involves tyrosine phosphorylation of signal transducer and activator of transcription (Stat)3 and Stat4

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700324

Distinct requirements for the naturally occurring splice forms Stat4alpha and Stat4beta in IL-12 responses

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700324

Activated STAT4 has an essential role in Th1 differentiation and proliferation that is independent of its role in the maintenance of IL-12R beta 2 chain expression and signaling

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700324

Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700324

Impaired interferon-gamma production as a consequence of STAT4 deficiency after autologous hematopoietic stem cell transplantation for lymphoma

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700324

Immune-cell lineage commitment: translation from mice to humans.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700324

Chromatin remodeling by the SWI/SNF-like BAF complex and STAT4 activation synergistically induce IL-12Rbeta2 expression during human Th1 cell differentiation

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700324

PU.1 expression delineates heterogeneity in primary Th2 cells.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700324

Critical role for STAT4 activation by type 1 interferons in the interferon-gamma response to viral infection

3 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19359411

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Residual Type 1 Immunity in Patients Genetically Deficient for Interleukin 12 Receptor β1 (IL-12Rβ1)

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19359411

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1182/BLOOD-2008-09-179820

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19359411%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19359411%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

1 reference