Acetaminophen modulates P-glycoprotein functional expression at the blood-brain barrier by a constitutive androstane receptor-dependent mechanism (Q37252086)

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scientific article published on 09 September 2013

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English	Acetaminophen modulates P-glycoprotein functional expression at the blood-brain barrier by a constitutive androstane receptor-dependent mechanism	scientific article published on 09 September 2013

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scholarly article

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Europe PubMed Central

PMC publication ID

19 August 2017

Acetaminophen modulates P-glycoprotein functional expression at the blood-brain barrier by a constitutive androstane receptor-dependent mechanism (English)

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PMC publication ID

19 August 2017

blood–brain barrier

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based on heuristic

inferred from title

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Thomas P. Davis

8

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24019224%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Lauren M Slosky

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Lauren M Slosky

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Brandon J Thompson

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13 June 2020

Lucy Sanchez-Covarrubias

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13 June 2020

Yifeng Zhang

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13 June 2020

Mei-Li Laracuente

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13 June 2020

Todd W Vanderah

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13 June 2020

Patrick T Ronaldson

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13 June 2020

publication date

9 September 2013

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19 August 2017

Molecular Pharmacology

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13 June 2020

84

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13 June 2020

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13 June 2020

774-786

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13 June 2020

describes a project that uses

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11 June 2022

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Targeted drug delivery to treat pain and cerebral hypoxia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3807077

6 September 2017

Acetaminophen-induced liver injury in rats and mice: comparison of protein adducts, mitochondrial dysfunction, and oxidative stress in the mechanism of toxicity.

1 reference

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6 September 2017

Induction of P-glycoprotein and Bcrp at the rat blood-brain barrier following a subchronic morphine treatment is mediated through NMDA/COX-2 activation

1 reference

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Targeting blood-brain barrier changes during inflammatory pain: an opportunity for optimizing CNS drug delivery

1 reference

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Paracetamol and selective and non-selective non-steroidal anti-inflammatory drugs for the reduction in morphine-related side-effects after major surgery: a systematic review

1 reference

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Inflammatory pain signals an increase in functional expression of organic anion transporting polypeptide 1a4 at the blood-brain barrier

1 reference

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Constitutive androstane receptor-mediated up-regulation of ATP-driven xenobiotic efflux transporters at the blood-brain barrier

1 reference

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Oxidative stress increases blood-brain barrier permeability and induces alterations in occludin during hypoxia-reoxygenation.

1 reference

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Dephosphorylation of threonine 38 is required for nuclear translocation and activation of human xenobiotic receptor CAR (NR1I3).

1 reference

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Evaluation of the P-glycoprotein (Abcb1) affinity status of a series of morphine analogs: comparative study with meperidine analogs to identify opioids with minimal P-glycoprotein interactions

1 reference

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6 September 2017

Transforming growth factor-beta signaling alters substrate permeability and tight junction protein expression at the blood-brain barrier during inflammatory pain

1 reference

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Occludin oligomeric assembly at tight junctions of the blood-brain barrier is disrupted by peripheral inflammatory hyperalgesia

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Intravenous paracetamol improves the quality of postoperative analgesia but does not decrease narcotic requirements

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6 September 2017

Nociceptive inhibition prevents inflammatory pain induced changes in the blood-brain barrier.

1 reference

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6 September 2017

Novel D-amino acid tetrapeptides produce potent antinociception by selectively acting at peripheral kappa-opioid receptors

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6 September 2017

CAR and PXR: the xenobiotic-sensing receptors

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Phenobarbital confers its diverse effects by activating the orphan nuclear receptor car

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6 September 2017

Effects of acetaminophen on morphine side-effects and consumption after major surgery: meta-analysis of randomized controlled trials

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Nicotine increases in vivo blood-brain barrier permeability and alters cerebral microvascular tight junction protein distribution.

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6 September 2017

Drug transport to the brain: key roles for the efflux pump P-glycoprotein in the blood-brain barrier

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6 September 2017

Modulation of acetaminophen-induced hepatotoxicity by the xenobiotic receptor CAR

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Expression of a full-length cDNA for the human "MDR1" gene confers resistance to colchicine, doxorubicin, and vinblastine

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Isolation of human mdr DNA sequences amplified in multidrug-resistant KB carcinoma cells

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Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells.

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Electrical resistance across the blood-brain barrier in anaesthetized rats: a developmental study

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6 September 2017

Regulation of P-glycoprotein by orphan nuclear receptors in human brain microvessel endothelial cells

1 reference

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14 September 2017

Reversible Ponceau staining as a loading control alternative to actin in Western blots

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A role for constitutive androstane receptor in the regulation of human intestinal MDR1 expression

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Genetic analysis of the multidrug transporter

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Targeted delivery of a substrate for P-glycoprotein to renal cysts in vitro

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Negative relationship between morphine analgesia and P-glycoprotein expression levels in the brain

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A population study of the frequency of high-dose acetaminophen prescribing and dispensing

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1 reference

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based on heuristic

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10.1124/MOL.113.086298

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24019224%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

PMC publication ID

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Europe PubMed Central

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13 June 2020

PubMed publication ID

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Europe PubMed Central

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13 June 2020

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