Genetic variations in cytokines and cytokine receptors associated with psoriasis found by genome-wide association (Q37284674)

19 August 2017

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title

Genetic variations in cytokines and cytokine receptors associated with psoriasis found by genome-wide association (English)

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genome-wide association study

19 August 2017

main subject

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author name string

Kristina Callis Duffin

series ordinal

1

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19 August 2017

Gerald G Krueger

series ordinal

2

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19 August 2017

language of work or name

English

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publication date

2 October 2008

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Journal of Investigative Dermatology

19 August 2017

published in

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19 August 2017

volume

129

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19 August 2017

issue

4

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19 August 2017

page(s)

827-833

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Association of variants of the interleukin-23 receptor gene with susceptibility to pediatric Crohn's disease

19 August 2017

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Interleukin-13 receptor in psoriatic keratinocytes: overexpression of the mRNA and underexpression of the protein

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Sequence variants in the genes for the interleukin-23 receptor (IL23R) and its ligand (IL12B) confer protection against psoriasis.

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An update on the genetics of psoriasis.

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A large-scale genetic association study confirms IL12B and leads to the identification of IL23R as psoriasis-risk genes

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Variants in the 5q31 cytokine gene cluster are associated with psoriasis

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Interleukin-13 stimulates interleukin-6 production by human keratinocytes. Similarity with interleukin-4.

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A genome-wide association study identifies IL23R as an inflammatory bowel disease gene

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IL-15 and psoriasis: another genetic link to Th17?

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The genetics of psoriasis 2001: the odyssey continues

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Monoclonal Anti–Interleukin 23 Reverses Active Colitis in a T Cell–Mediated Model in Mice

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Genetic polymorphism of IL-12 p40 gene in immune-mediated disease.

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Divergent effects of IL-12 and IL-23 on the production of IL-17 by human T cells

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Psoriasis is associated with increased beta-defensin genomic copy number

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Interleukin-23 drives innate and T cell-mediated intestinal inflammation

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Increased expression of interleukin 23 p19 and p40 in lesional skin of patients with psoriasis vulgaris

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Novel Crohn disease locus identified by genome-wide association maps to a gene desert on 5p13.1 and modulates expression of PTGER4

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Interleukin-15: a new cytokine target for the treatment of inflammatory diseases

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7 January 2021

Polymorphisms of the IL12B and IL23R genes are associated with psoriasis

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7 January 2021

Sequence and haplotype analysis supports HLA-C as the psoriasis susceptibility 1 gene

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7 January 2021

Epidemiology of psoriasis

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7 January 2021

Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility

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Genome-wide association study for Crohn's disease in the Quebec Founder Population identifies multiple validated disease loci

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Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis

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Inhibition of keratinocyte apoptosis by IL-15: a new parameter in the pathogenesis of psoriasis?

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Meta-analysis of genome-wide studies of psoriasis susceptibility reveals linkage to chromosomes 6p21 and 4q28-q31 in Caucasian and Chinese Hans population.

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Linking genetic susceptibility to Crohn's disease with Th17 cell function: IL-22 serum levels are increased in Crohn's disease and correlate with disease activity and IL23R genotype status

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7 January 2021

Polymorphisms in the IL-12beta and IL-23R genes are associated with psoriasis of early onset in a UK cohort.

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7 January 2021

Association between interleukin-1 receptor antagonist (IL-1ra) gene polymorphism and early and late-onset psoriasis

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7 January 2021

Interleukin-12 p40 gene (IL12B) 3'-untranslated region polymorphism is associated with susceptibility to atopic dermatitis and psoriasis vulgaris.

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7 January 2021

Differential activity of IL-12 and IL-23 in mucosal and systemic innate immune pathology.

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7 January 2021

IL-13 over-expression in skin is not confined to IgE-mediated skin inflammation

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7 January 2021

IL23R Arg381Gln is associated with childhood onset inflammatory bowel disease in Scotland

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7 January 2021

Resolution of psoriasis upon blockade of IL-15 biological activity in a xenograft mouse model

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7 January 2021

Up-regulation of interleukin-13 receptor alpha1 on human keratinocytes in the skin of psoriasis and atopic dermatitis

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7 January 2021

Amelioration of epidermal hyperplasia by TNF inhibition is associated with reduced Th17 responses

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7 January 2021

Evidence for a major psoriasis susceptibility locus at 6p21(PSORS1) and a novel candidate region at 4q31 by genome-wide scan in Chinese hans

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7 January 2021

Polymorphisms in interleukin-15 gene on chromosome 4q31.2 are associated with psoriasis vulgaris in Chinese population

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7 January 2021

Identifiers

DOI

10.1038/JID.2008.308

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Dimensions Publication ID

19 August 2017

1015955047

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