Intracellular trafficking of Notch receptors and ligands (Q37290434)

19 August 2017

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title

Intracellular trafficking of Notch receptors and ligands (English)

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19 August 2017

Christel Brou

1

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PubMed ID

18845146

19 August 2017

language of work or name

English

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publication date

25 September 2008

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Experimental Cell Research

19 August 2017

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19 August 2017

315

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19 August 2017

9

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19 August 2017

1549-1555

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Regulating the Notch pathway in embryonic, adult and old stem cells

19 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.010

The Notch1 receptor is cleaved constitutively by a furin-like convertase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.010

Rumi is a CAP10 domain glycosyltransferase that modifies Notch and is required for Notch signaling.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.010

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.010

A novel proteolytic cleavage involved in Notch signaling: the role of the disintegrin-metalloprotease TACE

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.010

kuzbanian-mediated cleavage of Drosophila Notch

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.010

A ligand-induced extracellular cleavage regulates gamma-secretase-like proteolytic activation of Notch1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.010

Requirement for dynamin during Notch signaling in Drosophila neurogenesis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.010

New positive regulators of lin-12 activity in Caenorhabditis elegans include the BRE-5/Brainiac glycosphingolipid biosynthesis enzyme.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.010

Phospholipid membrane composition affects EGF receptor and Notch signaling through effects on endocytosis during Drosophila development

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.010

Hrs mediates downregulation of multiple signalling receptors in Drosophila

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.010

Endocytic control of epithelial polarity and proliferation in Drosophila

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.010

The Drosophila tumor suppressor vps25 prevents nonautonomous overproliferation by regulating notch trafficking

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.010

Tumor suppressor properties of the ESCRT-II complex component Vps25 in Drosophila

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.010

Mutations in erupted, the Drosophila ortholog of mammalian tumor susceptibility gene 101, elicit non-cell-autonomous overgrowth

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.010

Presenilin-1, Nicastrin, Amyloid Precursor Protein, and γ-Secretase Activity Are Co-localized in the Lysosomal Membrane

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.010

AIP4/Itch regulates Notch receptor degradation in the absence of ligand

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.010

The tumor suppressors Merlin and Expanded function cooperatively to modulate receptor endocytosis and signaling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.010

Lethal giant discs, a novel C2-domain protein, restricts notch activation during endocytosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.010

The conserved c2 domain protein lethal (2) giant discs regulates protein trafficking in Drosophila

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.010

The Drosophila Notch inhibitor and tumor suppressor gene lethal (2) giant discs encodes a conserved regulator of endosomal trafficking

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.010

The itchy locus encodes a novel ubiquitin protein ligase that is disrupted in a18H mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.010

Drosophila Nedd4 regulates endocytosis of notch and suppresses its ligand-independent activation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.010

Regulation of notch endosomal sorting and signaling by Drosophila Nedd4 family proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.010

c-Cbl binding and ubiquitin-dependent lysosomal degradation of membrane-associated Notch1.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.010

Receptor regulation: beta-arrestin moves up a notch

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.010

Transduction of receptor signals by beta-arrestins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.010

Numb and alpha-Adaptin regulate Sanpodo endocytosis to specify cell fate in Drosophila external sensory organs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.010

Numb inhibits membrane localization of Sanpodo, a four-pass transmembrane protein, to promote asymmetric divisions in Drosophila

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.010

Fat facets and Liquid facets promote Delta endocytosis and Delta signaling in the signaling cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.010

Drosophila Epsin mediates a select endocytic pathway that DSL ligands must enter to activate Notch.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.010

Auxilin is essential for Delta signaling

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.010

Asymmetric Rab 11 endosomes regulate delta recycling and specify cell fate in the Drosophila nervous system

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.010

Sec15, a component of the exocyst, promotes notch signaling during the asymmetric division of Drosophila sensory organ precursors.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.010

The intracellular region of Notch ligands Dll1 and Dll3 regulates their trafficking and signaling activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.010

Two distinct E3 ubiquitin ligases have complementary functions in the regulation of delta and serrate signaling in Drosophila

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.010

The NHR1 domain of Neuralized binds Delta and mediates Delta trafficking and Notch signaling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.010

The neuralized homology repeat 1 domain of Drosophila neuralized mediates nuclear envelope association and delta-dependent inhibition of nuclear import

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.010

Neuralized contains a phosphoinositide-binding motif required downstream of ubiquitination for delta endocytosis and notch signaling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.010

Neuralized-2 regulates a Notch ligand in cooperation with Mind bomb-1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.010

Bearded family members inhibit Neuralized-mediated endocytosis and signaling activity of Delta in Drosophila.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.010

Dorsal-ventral pattern of Delta trafficking is established by a Snail-Tom-Neuralized pathway.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.010

Unidirectional Notch signaling depends on continuous cleavage of Delta

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.010

DSL ligand endocytosis physically dissociates Notch1 heterodimers before activating proteolysis can occur

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.010

Calcium depletion dissociates and activates heterodimeric notch receptors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.010

Notch subunit heterodimerization and prevention of ligand-independent proteolytic activation depend, respectively, on a novel domain and the LNR repeats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.010

Monoubiquitination and endocytosis direct gamma-secretase cleavage of activated Notch receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.010

Endosomal entry regulates Notch receptor activation in Drosophila melanogaster

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.010

On the phenotype and development of mutants of early neurogenesis inDrosophila melanogaster

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.010

The big brain aquaporin is required for endosome maturation and notch receptor trafficking

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2008.09.010

10.1016/J.YEXCR.2008.09.010

7 January 2021

Identifiers

DOI

1 reference

19 August 2017

1 reference

PubMed ID

18845146