Mrc1 phosphorylation in response to DNA replication stress is required for Mec1 accumulation at the stalled fork (Q37293173)

19 August 2017

Mrc1 phosphorylation in response to DNA replication stress is required for Mec1 accumulation at the stalled fork (English)

1 reference

Chromatin-modulating protein MRC1 YCL061C

19 August 2017

0 references

1 reference

DNA replication initiation factor CDC45 YLR103C

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

Tof1p YNL273W

1 reference

GOA release 2020-03-11

author name string

Maria L Naylor

1

1 reference

19 August 2017

Ju-mei Li

2

1 reference

19 August 2017

Alex J Osborn

3

1 reference

19 August 2017

Stephen J Elledge

4

1 reference

19 August 2017

language of work or name

English

0 references

publication date

10 June 2009

1 reference

Proceedings of the National Academy of Sciences of the United States of America

19 August 2017

6

1 reference

based on heuristic

inferred from page(s)

published in

1 reference

19 August 2017

106

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19 August 2017

31

1 reference

19 August 2017

12765-12770

1 reference

Mrc1 and DNA polymerase epsilon function together in linking DNA replication and the S phase checkpoint

19 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722297

Separate roles for the DNA damage checkpoint protein kinases in stabilizing DNA replication forks.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722297

Mrc1 and Tof1 regulate DNA replication forks in different ways during normal S phase

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722297

GINS maintains association of Cdc45 with MCM in replisome progression complexes at eukaryotic DNA replication forks

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722297

Mrc1 and Tof1 promote replication fork progression and recovery independently of Rad53.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722297

Uncoupling of unwinding from DNA synthesis implies regulation of MCM helicase by Tof1/Mrc1/Csm3 checkpoint complex.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722297

Mechanistically distinct roles for Sgs1p in checkpoint activation and replication fork maintenance.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722297

S-phase checkpoint proteins Tof1 and Mrc1 form a stable replication-pausing complex

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722297

DNA polymerase stabilization at stalled replication forks requires Mec1 and the RecQ helicase Sgs1.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722297

Mrc1 is a replication fork component whose phosphorylation in response to DNA replication stress activates Rad53.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722297

GINS, a novel multiprotein complex required for chromosomal DNA replication in budding yeast

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722297

The Cyclin E/Cdk2 Substrate and Cajal Body Component p220NPATActivates Histone Transcription through a Novel LisH-Like Domain

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722297

Mrc1 transduces signals of DNA replication stress to activate Rad53.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722297

Two checkpoint complexes are independently recruited to sites of DNA damage in vivo

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722297

The DNA replication checkpoint response stabilizes stalled replication forks

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722297

Tof1p regulates DNA damage responses during S phase in Saccharomyces cerevisiae

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722297

Recovery from DNA replicational stress is the essential function of the S-phase checkpoint pathway

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722297

Components and dynamics of DNA replication complexes in S. cerevisiae: redistribution of MCM proteins and Cdc45p during S phase

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722297

The novel DNA damage checkpoint protein ddc1p is phosphorylated periodically during the cell cycle and in response to DNA damage in budding yeast.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722297

RAD9 and DNA polymerase epsilon form parallel sensory branches for transducing the DNA damage checkpoint signal in Saccharomyces cerevisiae

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722297

DNA polymerase epsilon links the DNA replication machinery to the S phase checkpoint

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722297

Mrc1 is required for normal progression of replication forks throughout chromatin in S. cerevisiae.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722297

Exo1 processes stalled replication forks and counteracts fork reversal in checkpoint-defective cells

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722297

A central role for DNA replication forks in checkpoint activation and response

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722297

Mrc1 channels the DNA replication arrest signal to checkpoint kinase Cds1.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2722297

Checkpoint-mediated control of replisome–fork association and signalling in response to replication pausing

3 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0904623106

21 January 2018

Identifiers

DOI

10.1073/PNAS.0904623106

1 reference

19 August 2017

0 references

1 reference

19 August 2017

PubMed publication ID

19515819

1 reference