Cytokine-induced beta-cell apoptosis is NO-dependent, mitochondria-mediated and inhibited by BCL-XL. (Q37293874)

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29 December 2019

title

Cytokine-induced beta-cell apoptosis is NO-dependent, mitochondria-mediated and inhibited by BCL-XL (English)

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29 December 2019

0 references

1 reference

2

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29 December 2019

Thomas Ritter

3

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29 December 2019

Timothy O'Brien

4

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29 December 2019

Afshin Samali

5

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29 December 2019

author name string

C Holohan

1

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29 December 2019

publication date

10 December 2007

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Journal of Cellular and Molecular Medicine

29 December 2019

published in

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29 December 2019

volume

12

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29 December 2019

issue

2

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29 December 2019

page(s)

591-606

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Distinct mechanisms of cardiomyocyte apoptosis induced by doxorubicin and hypoxia converge on mitochondria and are inhibited by Bcl-xL

29 December 2019

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Cytokines downregulate the sarcoendoplasmic reticulum pump Ca2+ ATPase 2b and deplete endoplasmic reticulum Ca2+, leading to induction of endoplasmic reticulum stress in pancreatic beta-cells

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A choice of death--the signal-transduction of immune-mediated beta-cell apoptosis

6 September 2017

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6 September 2017

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Regulation of mitochondrial respiration by nitric oxide inhibition of cytochrome c oxidase

6 September 2017

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The pro-apoptotic proteins, Bid and Bax, cause a limited permeabilization of the mitochondrial outer membrane that is enhanced by cytosol

6 September 2017

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Presence of a pre-apoptotic complex of pro-caspase-3, Hsp60 and Hsp10 in the mitochondrial fraction of jurkat cells

6 September 2017

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Mitochondria and apoptosis

6 September 2017

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Multiple NF-kappaB enhancer elements regulate cytokine induction of the human inducible nitric oxide synthase gene

6 September 2017

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Movement of Bax from the cytosol to mitochondria during apoptosis

6 September 2017

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The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis

6 September 2017

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An interferon-gamma-activated site (GAS) is necessary for full expression of the mouse iNOS gene in response to interferon-gamma and lipopolysaccharide

6 September 2017

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Role of transcription factor NF-kappa B/Rel in induction of nitric oxide synthase

6 September 2017

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The cytokine responsive vascular smooth muscle cell enhancer of inducible nitric oxide synthase. Activation by nuclear factor-kappa B.

6 September 2017

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Beta cell cytoprotection using lentiviral vector-based iNOS-specific shRNA delivery.

6 September 2017

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Pro- and antiapoptotic proteins regulate apoptosis but do not protect against cytokine-mediated cytotoxicity in rat islets and beta-cell lines

14 September 2017

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beta cell cytoprotective strategies: establishing the relative roles for iNOS and ROS.

14 September 2017

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Purification of adenovirus and adeno-associated virus: comparison of novel membrane-based technology to conventional techniques.

14 September 2017

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Regulation of HAX-1 anti-apoptotic protein by Omi/HtrA2 protease during cell death

14 September 2017

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Discovery of Gene Networks Regulating Cytokine-Induced Dysfunction and Apoptosis in Insulin-Producing INS-1 Cells

14 September 2017

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Insulin-dependent diabetes mellitus as an autoimmune disease

14 September 2017

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Nitric oxide and pancreatic beta-cell destruction in insulin dependent diabetes mellitus: don't take NO for an answer

14 September 2017

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Bax-induced caspase activation and apoptosis via cytochrome c release from mitochondria is inhibitable by Bcl-xL.

14 September 2017

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Apoptosis -- the story so far....

28 September 2017

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Characterization of 911: a new helper cell line for the titration and propagation of early region 1-deleted adenoviral vectors.

28 September 2017

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Cytokine-induced apoptotic cell death in a mouse pancreatic beta-cell line: inhibition by Bcl-2.

28 September 2017

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Interleukin-1 beta-induced nitric oxide production activates apoptosis in pancreatic RINm5F cells

28 September 2017

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p53 expression in nitric oxide‐induced apoptosis

28 September 2017

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28 September 2017

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TNF-alpha and IFN-gamma potentiate the deleterious effects of IL-1 beta on mouse pancreatic islets mainly via generation of nitric oxide

26 June 2018

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Requirement for transcription factor IRF-1 in NO synthase induction in macrophages.

26 June 2018

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Omi/HtrA2 protease mediates cisplatin-induced cell death in renal cells.

26 June 2018

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Identification of deficient mitochondrial signaling in apoptosis resistant leukemia cells by flow cytometric analysis of intracellular cytochrome c, caspase-3 and apoptosis.

3 September 2018

1 reference

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Role of calcium in pancreatic islet cell death by IFN-gamma/TNF-alpha

3 September 2018

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Interleukin-1 plus gamma-interferon-induced pancreatic beta-cell dysfunction is mediated by beta-cell nitric oxide production

3 September 2018

1 reference

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3 September 2018

Mechanisms of apoptosis

1 reference

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Mechanisms of cytokine-induced destruction of rat insulinoma cells: the role of nitric oxide

20 October 2018

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Crossref

https://api.crossref.org/works/10.1111%2FJ.1582-4934.2007.00191.X

Death by a thousand cuts: an ever increasing list of caspase substrates

21 January 2018

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12 December 2020

Cytokines and their roles in pancreatic islet beta-cell destruction and insulin-dependent diabetes mellitus

1 reference

12 December 2020

Inducible nitric oxide synthase (iNOS) expression upregulates p21 and inhibits vascular smooth muscle cell proliferation through p42/44 mitogen-activated protein kinase activation and independent of p53 and cyclic guanosine monophosphate

1 reference

12 December 2020

Interleukin-1 receptor antagonist prevents low dose streptozotocin induced diabetes in mice

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12 December 2020

Apoptosis: cell death defined by caspase activation

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12 December 2020

Mitochondrial Nitric-oxide Synthase Stimulation Causes CytochromecRelease from Isolated Mitochondria

1 reference

12 December 2020

Inducible nitric oxide synthase in the liver: regulation and function

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12 December 2020

1 reference

12 December 2020

10.1111/J.1582-4934.2007.00191.X

Identifiers

DOI

1 reference

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29 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18081694%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

PubMed publication ID

18081694

1 reference