Molecular mechanisms that control mouse and human TCR-alphabeta and TCR-gammadelta T cell development (Q37299851)

19 August 2017

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title

Molecular mechanisms that control mouse and human TCR-alphabeta and TCR-gammadelta T cell development (English)

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19 August 2017

Ellen V Rothenberg

2

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Tom Taghon

series ordinal

1

object named as

Tom Taghon

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19 August 2017

17 October 2008

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Seminars in Immunopathology

19 August 2017

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19 August 2017

30

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19 August 2017

4

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19 August 2017

383-398

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https://scigraph.springernature.com/pub.10.1007/s00281-008-0134-3

19 August 2017

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cites work

Evolutionary origins of lymphocytes: ensembles of T cell and B cell transcriptional regulators in a cartilaginous fish

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T cell lineage determination precedes the initiation of TCR beta gene rearrangement.

21 January 2018

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TCRgamma silencing during alphabeta T cell development depends upon pre-TCR-induced proliferation.

21 January 2018

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Human alpha beta and gamma delta thymocyte development: TCR gene rearrangements, intracellular TCR beta expression, and gamma delta developmental potential--differences between men and mice

21 January 2018

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Early growth response transcription factors are required for development of CD4(-)CD8(-) thymocytes to the CD4(+)CD8(+) stage.

21 January 2018

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STAT5 is required for thymopoiesis in a development stage-specific manner

21 January 2018

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Deranged early T cell development in immunodeficient strains of nonobese diabetic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-008-0134-3

Propensity of adult lymphoid progenitors to progress to DN2/3 stage thymocytes with Notch receptor ligation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-008-0134-3

Regulation of alphabeta/gammadelta T cell development by the activator protein 1 transcription factor c-Jun.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-008-0134-3

Developmental and functional defects of thymic and epidermal V gamma 3 cells in IL-15-deficient and IFN regulatory factor-1-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-008-0134-3

Active form of Notch imposes T cell fate in human progenitor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-008-0134-3

Molecular dissection of prethymic progenitor entry into the T lymphocyte developmental pathway

21 January 2018

1 reference

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Expression of TCR alpha beta partly rescues developmental arrest and apoptosis of alpha beta T cells in Bcl11b-/- mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-008-0134-3

Transcription from a murine T-cell receptor V beta promoter depends on a conserved decamer motif similar to the cyclic AMP response element

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-008-0134-3

Identification and functional characterization of the human T-cell receptor beta gene transcriptional enhancer: common nuclear proteins interact with the transcriptional regulatory elements of the T-cell receptor alpha and beta genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-008-0134-3

TCR- and CD28-mediated recruitment of phosphodiesterase 4 to lipid rafts potentiates TCR signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-008-0134-3

RORgammat recruits steroid receptor coactivators to ensure thymocyte survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-008-0134-3

E2A deficiency leads to abnormalities in alphabeta T-cell development and to rapid development of T-cell lymphomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-008-0134-3

E2A and HEB are required to block thymocyte proliferation prior to pre-TCR expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-008-0134-3

Cutting edge: histone acetylation and recombination at the TCR gamma locus follows IL-7 induction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-008-0134-3

Launching the T-cell-lineage developmental programme

21 January 2018

1 reference

12 December 2020

T cell receptor ligation induces interleukin (IL) 2R beta chain expression in rat CD4,8 double positive thymocytes, initiating an IL-2-dependent differentiation pathway of CD8 alpha+/beta- T cells

1 reference

12 December 2020

Regulation of B versus T lymphoid lineage fate decision by the proto-oncogene LRF.

1 reference

12 December 2020

Blockage of alpha beta T-cell development by TCR gamma delta transgenes

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12 December 2020

Inhibition of gamma delta T cell development and early thymocyte maturation in IL-7 -/- mice.

1 reference

12 December 2020

Functions of E2A-HEB heterodimers in T-cell development revealed by a dominant negative mutation of HEB

1 reference

12 December 2020

An HMG-box-containing T-cell factor required for thymocyte differentiation.

1 reference

12 December 2020

AML-1 is required for megakaryocytic maturation and lymphocytic differentiation, but not for maintenance of hematopoietic stem cells in adult hematopoiesis

1 reference

12 December 2020

Complex expression patterns of lymphocyte-specific genes during the development of cartilaginous fish implicate unique lymphoid tissues in generating an immune repertoire.

1 reference

12 December 2020

Evolution of antigen binding receptors

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12 December 2020

A new T-cell receptor gene located within the alpha locus and expressed early in T-cell differentiation

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12 December 2020

Bcl11b is required for differentiation and survival of αβ T lymphocytes

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12 December 2020

Defective development of gamma/delta T cells in interleukin 7 receptor-deficient mice is due to impaired expression of T cell receptor gamma genes

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12 December 2020

Differential requirements for Runx proteins in CD4 repression and epigenetic silencing during T lymphocyte development.

1 reference

12 December 2020

Cooperating pre-T-cell receptor and TCF-1-dependent signals ensure thymocyte survival.

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12 December 2020

Lymphotoxin-mediated regulation of gammadelta cell differentiation by alphabeta T cell progenitors

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12 December 2020

Positive and negative regulation of V(D)J recombination by the E2A proteins

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12 December 2020

Induction of the early growth response (Egr) family of transcription factors during thymic selection

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12 December 2020

Phenotypic and functional maturation of TCR gammadelta cells in the human thymus.

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12 December 2020

TCR3: a third T-cell receptor in the chicken

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12 December 2020

Characterization of avian T-cell receptor gamma genes

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12 December 2020

Thymocyte proliferation induced by pre-T cell receptor signaling is maintained through polycomb gene product Bmi-1-mediated Cdkn2a repression

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12 December 2020

Mast cell lineage diversion of T lineage precursors by the essential T cell transcription factor GATA-3

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12 December 2020

The transcription factor interferon regulatory factor 1 (IRF-1) is important during the maturation of natural killer 1.1+ T cell receptor-alpha/beta+ (NK1+ T) cells, natural killer cells, and intestinal intraepithelial T cells

1 reference

12 December 2020

Polycomb silencing mechanisms in Drosophila.

1 reference

12 December 2020

Commitment to natural killer cells requires the helix-loop-helix inhibitor Id2

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12 December 2020

Precise developmental regulation of Ets family transcription factors during specification and commitment to the T cell lineage

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12 December 2020

Early expression of a T-cell receptor beta-chain transgene suppresses rearrangement of the V gamma 4 gene segment

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12 December 2020

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12 December 2020

Notch signaling controls the generation and differentiation of early T lineage progenitors

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12 December 2020

The role of Notch and IL-7 signaling in early thymocyte proliferation and differentiation.

1 reference

12 December 2020

A limited role for beta-selection during gamma delta T cell development.

1 reference

12 December 2020

T cell lineage choice and differentiation in the absence of the RNase III enzyme Dicer

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12 December 2020

Prominence of gamma delta T cells in the ruminant immune system.

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12 December 2020

Human bone marrow CD34+ progenitor cells mature to T cells on OP9-DL1 stromal cell line without thymus microenvironment

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12 December 2020

Dynamics of Thymus-Colonizing Cells during Human Development

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12 December 2020

A critical role for Dnmt1 and DNA methylation in T cell development, function, and survival.

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12 December 2020

On the role of the pre-T cell receptor in alphabeta versus gammadelta T lineage commitment

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12 December 2020

Differential effects of Notch ligands Delta-1 and Jagged-1 in human lymphoid differentiation

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12 December 2020

Evidence that gammadelta versus alphabeta T cell fate determination is initiated independently of T cell receptor signaling.

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12 December 2020

alpha, beta, gamma, and delta T cell antigen receptor genes arose early in vertebrate phylogeny.

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12 December 2020

The WC1(+) gammadelta T-cell population in cattle: a possible role in resistance to intracellular infection

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12 December 2020

A critical role for the cytoplasmic tail of pTα in T lymphocyte development

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12 December 2020

Requirement for RORgamma in thymocyte survival and lymphoid organ development

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12 December 2020

Down-regulation of the orphan nuclear receptor ROR gamma t is essential for T lymphocyte maturation

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12 December 2020

E2A proteins enforce a proliferation checkpoint in developing thymocytes

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12 December 2020

The earliest thymic progenitors for T cells possess myeloid lineage potential.

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12 December 2020

Notch regulation of lymphocyte development and function.

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12 December 2020

T-cell receptor gamma delta and gamma transgenic mice suggest a role of a gamma gene silencer in the generation of alpha beta T cells.

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12 December 2020

Progression of regulatory gene expression states in fetal and adult pro-T-cell development

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12 December 2020

Acquisition of a functional T cell receptor during T lymphocyte development is enforced by HEB and E2A transcription factors

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12 December 2020

Developmental and molecular characterization of emerging beta- and gammadelta-selected pre-T cells in the adult mouse thymus

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12 December 2020

Stage-specific and differential notch dependency at the alphabeta and gammadelta T lineage bifurcation

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12 December 2020

The beta-catenin--TCF-1 pathway ensures CD4(+)CD8(+) thymocyte survival

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12 December 2020

Hierarchy of Notch-Delta interactions promoting T cell lineage commitment and maturation

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12 December 2020

Transgenic expression of the p16(INK4a) cyclin-dependent kinase inhibitor leads to enhanced apoptosis and differentiation arrest of CD4-CD8- immature thymocytes

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12 December 2020

Notch signaling induces cytoplasmic CD3 epsilon expression in human differentiating NK cells.

1 reference

12 December 2020

Increased TSLP availability restores T- and B-cell compartments in adult IL-7 deficient mice

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12 December 2020

A novel role for HEB downstream or parallel to the pre-TCR signaling pathway during alpha beta thymopoiesis.

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12 December 2020

Wnt signaling in the thymus is regulated by differential expression of intracellular signaling molecules

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12 December 2020

Glucose transporter 1 expression identifies a population of cycling CD4+ CD8+ human thymocytes with high CXCR4-induced chemotaxis.

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12 December 2020

Sustained Notch1 signaling instructs the earliest human intrathymic precursors to adopt a gammadelta T-cell fate in fetal thymus organ culture.

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12 December 2020

Notch 1-deficient common lymphoid precursors adopt a B cell fate in the thymus.

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12 December 2020

The IL-7 receptor controls the accessibility of the TCRgamma locus by Stat5 and histone acetylation

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12 December 2020

Inhibition of T cell and promotion of natural killer cell development by the dominant negative helix loop helix factor Id3.

1 reference

12 December 2020

Adult T-cell progenitors retain myeloid potential

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12 December 2020

Early growth response gene 3 regulates thymocyte proliferation during the transition from CD4-CD8- to CD4+CD8+

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12 December 2020

Regulatory elements in the promoter of a murine TCRD V gene segment

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12 December 2020

Dynamic regulation of miRNA expression in ordered stages of cellular development.

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12 December 2020

Basic helix-loop-helix proteins E2A and HEB induce immature T-cell receptor rearrangements in nonlymphoid cells.

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12 December 2020

Different thresholds of Notch signaling bias human precursor cells toward B-, NK-, monocytic/dendritic-, or T-cell lineage in thymus microenvironment

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12 December 2020

Heterogeneity among DN1 prothymocytes reveals multiple progenitors with different capacities to generate T cell and non-T cell lineages

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12 December 2020

Premature expression of T cell receptor (TCR)alphabeta suppresses TCRgammadelta gene rearrangement but permits development of gammadelta lineage T cells

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12 December 2020

Deficient T cell fate specification in mice with an induced inactivation of Notch1.

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12 December 2020

Distinct roles of IL-7 and stem cell factor in the OP9-DL1 T-cell differentiation culture system

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12 December 2020

New insights on human T cell development by quantitative T cell receptor gene rearrangement studies and gene expression profiling.

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12 December 2020

Helix-loop-helix proteins and lymphocyte development

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12 December 2020

Regulation of gammadelta versus alphabeta T lymphocyte differentiation by the transcription factor SOX13.

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12 December 2020

Selection of the cutaneous intraepithelial γδ+ T cell repertoire by a thymic stromal determinant

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12 December 2020

Molecular genetics of T cell development

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12 December 2020

Regulation of T cell receptor beta gene rearrangements and allelic exclusion by the helix-loop-helix protein, E47

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12 December 2020

Identification of T-cell receptor alpha-chain genes in the chicken

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12 December 2020

Neonatal thymectomy identifies two major pools of sessile and recirculating peripheral T cells which appear to be under separate homeostatic control

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12 December 2020

Akt1 and Akt2 are required for alphabeta thymocyte survival and differentiation.

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12 December 2020

Selectively impaired development of intestinal T cell receptor gamma delta+ cells and liver CD4+ NK1+ T cell receptor alpha beta+ cells in T cell factor-1-deficient mice

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12 December 2020

Long-term, multilineage hematopoiesis occurs in the combined absence of beta-catenin and gamma-catenin

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12 December 2020

Induction of a diverse T cell receptor gamma/delta repertoire by the helix-loop-helix proteins E2A and HEB in nonlymphoid cells

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12 December 2020

The Ets-1 transcription factor is required for complete pre-T cell receptor function and allelic exclusion at the T cell receptor beta locus

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12 December 2020

Delayed, asynchronous, and reversible T-lineage specification induced by Notch/Delta signaling

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12 December 2020

Disruption of alpha beta but not of gamma delta T cell development by overexpression of the helix-loop-helix protein Id3 in committed T cell progenitors

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12 December 2020

Regulation of lymphoid development, differentiation, and function by the Notch pathway.

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12 December 2020

Notch activity influences the alphabeta versus gammadelta T cell lineage decision

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12 December 2020

The role of Brg1, a catalytic subunit of mammalian chromatin-remodeling complexes, in T cell development

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12 December 2020

Inactivation of Notch1 impairs VDJbeta rearrangement and allows pre-TCR-independent survival of early alpha beta Lineage Thymocytes.

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12 December 2020

Interplay between RORgammat, Egr3, and E proteins controls proliferation in response to pre-TCR signals.

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12 December 2020

Induction of T cell development from hematopoietic progenitor cells by delta-like-1 in vitro.

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12 December 2020

Notch/Delta signaling constrains reengineering of pro-T cells by PU.1.

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12 December 2020

Beta-selection is associated with the onset of CD8beta chain expression on CD4(+)CD8alphaalpha(+) pre-T cells during human intrathymic development.

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12 December 2020

TCR signal strength influences alphabeta/gammadelta lineage fate

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12 December 2020

Runx3 regulates dendritic epidermal T cell development

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12 December 2020

Critical involvement of Tcf-1 in expansion of thymocytes

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12 December 2020

A human postnatal lymphoid progenitor capable of circulating and seeding the thymus

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12 December 2020

Two waves of recombinase gene expression in developing thymocytes

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12 December 2020

Human intrathymic lineage commitment is marked by differential CD7 expression: identification of CD7- lympho-myeloid thymic progenitors

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12 December 2020

T cell receptor-instructed alphabeta versus gammadelta lineage commitment revealed by single-cell analysis.

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12 December 2020

Visualization of the earliest steps of gammadelta T cell development in the adult thymus.

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12 December 2020

IL-7 receptor signals inhibit expression of transcription factors TCF-1, LEF-1, and RORgammat: impact on thymocyte development.

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12 December 2020

Differential synergy of Notch and T cell receptor signaling determines alphabeta versus gammadelta lineage fate.

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12 December 2020

Impaired fetal T cell development and perinatal lethality in mice lacking the cAMP response element binding protein

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12 December 2020

Integrated morphogen signal inputs in gammadelta versus alphabeta T-cell differentiation.

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12 December 2020

Redundant regulation of T cell differentiation and TCRalpha gene expression by the transcription factors LEF-1 and TCF-1

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12 December 2020

Differential effects of interleukin-15 and interleukin-2 on differentiation of bipotential T/natural killer progenitor cells

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12 December 2020

Ablation of ribosomal protein L22 selectively impairs alphabeta T cell development by activation of a p53-dependent checkpoint

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12 December 2020

Regulation of intrathymic T-cell development by Lunatic Fringe- Notch1 interactions

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12 December 2020

E proteins and Notch signaling cooperate to promote T cell lineage specification and commitment

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12 December 2020

Notch promotes survival of pre-T cells at the beta-selection checkpoint by regulating cellular metabolism

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12 December 2020

Interleukin 15 controls the generation of the restricted T cell receptor repertoire of gamma delta intestinal intraepithelial lymphocytes

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12 December 2020

Delta-like 1 is necessary for the generation of marginal zone B cells but not T cells in vivo

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12 December 2020

Early thymocyte development is regulated by modulation of E2A protein activity

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12 December 2020

The role of the Runx transcription factors in thymocyte differentiation and in homeostasis of naive T cells.

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12 December 2020

Interleukin-7 is a critical growth factor in early human T-cell development.

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12 December 2020

Maintenance of T cell specification and differentiation requires recurrent notch receptor-ligand interactions

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12 December 2020

Different initiation of pre-TCR and gammadeltaTCR signalling

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12 December 2020

Thymic origin of intestinal alphabeta T cells revealed by fate mapping of RORgammat+ cells

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12 December 2020

Thymopoiesis independent of common lymphoid progenitors

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12 December 2020

Attenuation of gammadeltaTCR signaling efficiently diverts thymocytes to the alphabeta lineage.

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12 December 2020

Induction of T-cell development from human cord blood hematopoietic stem cells by Delta-like 1 in vitro

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12 December 2020

Defects in limb, craniofacial, and thymic development in Jagged2 mutant mice

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12 December 2020

Development and selection of gammadelta T cells

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12 December 2020

Reprogramming of committed T cell progenitors to macrophages and dendritic cells by C/EBP alpha and PU.1 transcription factors.

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12 December 2020

10.1007/S00281-008-0134-3

Identifiers

DOI

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19 August 2017

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PubMed ID

18925397