An essential role for the IL-2 receptor in Treg cell function (Q37351745)

19 August 2017

An essential role for the IL-2 receptor in Treg cell function (English)

1 reference

19 August 2017

0 references

7

Georg Gasteiger

1 reference

19 August 2017

Takatoshi Chinen

1

1 reference

19 August 2017

Arun K Kannan

2

1 reference

19 August 2017

Andrew G Levine

3

1 reference

19 August 2017

Xiying Fan

4

1 reference

19 August 2017

Ulf Klein

5

1 reference

19 August 2017

Ye Zheng

6

1 reference

19 August 2017

Yongqiang Feng

8

1 reference

19 August 2017

Jason D Fontenot

9

1 reference

19 August 2017

Alexander Y Rudensky

10

1 reference

19 August 2017

language of work or name

English

0 references

publication date

5 September 2016

1 reference

full work available at URL

19 August 2017

http://eprints.whiterose.ac.uk/138153

content deliverer

White Rose Research Online

0 references

1 reference

19 August 2017

17

1 reference

19 August 2017

1322-1333

1 reference

19 August 2017

11

1 reference

https://scigraph.springernature.com/pub.10.1038/ni.3540

19 August 2017

0 references

cites work

Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2

1 reference

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Continuous requirement for the TCR in regulatory T cell function

6 September 2017

1 reference

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Inflammation-induced repression of chromatin bound by the transcription factor Foxp3 in regulatory T cells

6 September 2017

1 reference

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Lineage stability and phenotypic plasticity of Foxp3⁺ regulatory T cells.

6 September 2017

1 reference

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Trimmomatic: a flexible trimmer for Illumina sequence data

6 September 2017

1 reference

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CCR7 provides localized access to IL-2 and defines homeostatically distinct regulatory T cell subsets

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5071159

Count-based differential expression analysis of RNA sequencing data using R and Bioconductor

6 September 2017

1 reference

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Construction of self-recognizing regulatory T cells from conventional T cells by controlling CTLA-4 and IL-2 expression

6 September 2017

1 reference

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Comparative Genomics Reveals Key Gain-of-Function Events in Foxp3 during Regulatory T Cell Evolution

6 September 2017

1 reference

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Enrichment map: a network-based method for gene-set enrichment visualization and interpretation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5071159

Competing feedback loops shape IL-2 signaling between helper and regulatory T lymphocytes in cellular microenvironments.

6 September 2017

1 reference

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A dominant, coordinated T regulatory cell-IgA response to the intestinal microbiota.

6 September 2017

1 reference

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Runx-CBFbeta complexes control expression of the transcription factor Foxp3 in regulatory T cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5071159

Analysis of adhesion molecules, target cells, and role of IL-2 in human FOXP3+ regulatory T cell suppressor function

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5071159

Heterogeneity of natural Foxp3+ T cells: a committed regulatory T-cell lineage and an uncommitted minor population retaining plasticity

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5071159

A novel signaling pathway impact analysis.

6 September 2017

1 reference

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Regulatory T cell-derived interleukin-10 limits inflammation at environmental interfaces

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5071159

A two-step process for thymic regulatory T cell development.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5071159

CD4+CD25+Foxp3+ regulatory T cells induce cytokine deprivation-mediated apoptosis of effector CD4+ T cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5071159

Nonredundant roles for Stat5a/b in directly regulating Foxp3

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5071159

Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5071159

Regulatory T cells inhibit stable contacts between CD4+ T cells and dendritic cells in vivo

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5071159

A function for interleukin 2 in Foxp3-expressing regulatory T cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5071159

BiNGO: a Cytoscape plugin to assess overrepresentation of gene ontology categories in biological networks

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5071159

Homeostatic maintenance of natural Foxp3(+) CD25(+) CD4(+) regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralization

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5071159

Tolerance, not immunity, crucially depends on IL-2.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5071159

Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5071159

Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5071159

Control of regulatory T cell development by the transcription factor Foxp3

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5071159

Interleukin 2 signaling is required for CD4(+) regulatory T cell function

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5071159

Disruption of overlapping transcripts in the ROSA beta geo 26 gene trap strain leads to widespread expression of beta-galactosidase in mouse embryos and hematopoietic cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5071159

Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5071159

The multi-subunit interleukin-2 receptor

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5071159

Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC gene

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5071159

Identification and characterization of a constitutively active STAT5 mutant that promotes cell proliferation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5071159

CD25+ CD4+ T cells compete with naive CD4+ T cells for IL-2 and exploit it for the induction of IL-10 production.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5071159

Cutting edge: mechanisms of IL-2-dependent maintenance of functional regulatory T cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5071159

Stability of the regulatory T cell lineage in vivo.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5071159

Role of STAT5 in controlling cell survival and immunoglobulin gene recombination during pro-B cell development

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5071159

Continuous T cell receptor signals maintain a functional regulatory T cell pool.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5071159

Control of the inheritance of regulatory T cell identity by a cis element in the Foxp3 locus

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5071159

Foxp3(+) regulatory T cells promote T helper 17 cell development in vivo through regulation of interleukin-2.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5071159

IL-2, -7, and -15, but not thymic stromal lymphopoeitin, redundantly govern CD4+Foxp3+ regulatory T cell development

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5071159

IL-2 receptor beta-dependent STAT5 activation is required for the development of Foxp3+ regulatory T cells.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5071159

Selective stimulation of T cell subsets with antibody-cytokine immune complexes.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5071159

Cutting edge: IL-2 is critically required for the in vitro activation of CD4+CD25+ T cell suppressor function.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5071159

IL-2 secretion by CD4+ T cells in vivo is rapid, transient, and influenced by TCR-specific competition.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5071159

Regulatory T cell properties of chicken CD4+CD25+ cells

2 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27595233

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Homeostasis of peripheral CD4+ T cells: IL-2R alpha and IL-2 shape a population of regulatory cells that controls CD4+ T cell numbers

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27595233

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

CD4 regulatory T cells prevent lethal autoimmunity in IL-2Rbeta-deficient mice. Implications for the nonredundant function of IL-2

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27595233

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NI.3540

1 reference

Dimensions Publication ID

19 August 2017

0 references

1 reference

19 August 2017

1 reference