The Drosophila BEACH family protein, blue cheese, links lysosomal axon transport with motor neuron degeneration (Q37361252)

19 August 2017

The Drosophila BEACH family protein, blue cheese, links lysosomal axon transport with motor neuron degeneration (English)

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19 August 2017

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Blue cheese Dmel_CG14001

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GOA release 2020-03-11

author name string

Angeline Lim

series ordinal

1

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19 August 2017

Rachel Kraut

series ordinal

2

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19 August 2017

language of work or name

English

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publication date

1 January 2009

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19 August 2017

Journal of Neuroscience

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19 August 2017

29

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19 August 2017

4

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19 August 2017

951-963

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describes a project that uses

19 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3849423/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Genetic modifiers of the Drosophila blue cheese gene link defects in lysosomal transport with decreased life span and altered ubiquitinated-protein profiles

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Bchs, a BEACH domain protein, antagonizes Rab11 in synapse morphogenesis and other developmental events.

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Dynein mutations impair autophagic clearance of aggregate-prone proteins

6 September 2017

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A mutation in dynein rescues axonal transport defects and extends the life span of ALS mice

6 September 2017

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In vivo imaging of axonal degeneration and regeneration in the injured spinal cord

6 September 2017

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6 September 2017

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Dynactin: coordinating motors with opposite inclinations

6 September 2017

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blue cheese mutations define a novel, conserved gene involved in progressive neural degeneration.

6 September 2017

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The role of BEACH proteins in Dictyostelium

6 September 2017

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Intraneuronal Alzheimer abeta42 accumulates in multivesicular bodies and is associated with synaptic pathology

6 September 2017

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6 September 2017

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6 September 2017

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Aggregate-prone proteins with polyglutamine and polyalanine expansions are degraded by autophagy

6 September 2017

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Kinesin molecular motors: transport pathways, receptors, and human disease

6 September 2017

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Mutations in the novel membrane protein spinster interfere with programmed cell death and cause neural degeneration in Drosophila melanogaster

6 September 2017

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6 September 2017

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6 September 2017

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Cytoplasmic dynein, the dynactin complex, and kinesin are interdependent and essential for fast axonal transport

6 September 2017

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Assembly and maturation of the Drosophila larval neuromuscular junction

6 September 2017

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Mosaic analysis with a repressible cell marker for studies of gene function in neuronal morphogenesis

6 September 2017

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A modular misexpression screen in Drosophila detecting tissue-specific phenotypes

6 September 2017

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Axonopathy and transport deficits early in the pathogenesis of Alzheimer's disease

6 September 2017

1 reference

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Slowing of axonal transport is a very early event in the toxicity of ALS-linked SOD1 mutants to motor neurons

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849423

Identification of necrotic cell death by the TUNEL assay in the hypoxic-ischemic neonatal rat brain.

26 June 2018

1 reference

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inscuteable, a neural precursor gene of Drosophila, encodes a candidate for a cytoskeleton adaptor protein

26 June 2018

1 reference

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Stereotypic morphology of glutamatergic synapses on identified muscle cells of Drosophila larvae.

26 June 2018

1 reference

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Increased App expression in a mouse model of Down's syndrome disrupts NGF transport and causes cholinergic neuron degeneration.

26 June 2018

1 reference

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Microtubule-associated protein MAP1A, MAP1B, and MAP2 proteolysis during soluble amyloid beta-peptide-induced neuronal apoptosis. Synergistic involvement of calpain and caspase-3.

2 September 2018

1 reference

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Death of an axon: studying axon loss in development and disease

2 September 2018

1 reference

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Drosophila Vps16A is required for trafficking to lysosomes and biogenesis of pigment granules

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849423

Neurobeachin is essential for neuromuscular synaptic transmission.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849423

Axonal defects in mouse models of motoneuron disease

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849423

Neuropathogenic forms of huntingtin and androgen receptor inhibit fast axonal transport

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849423

Disruption of Axonal Transport by Loss of Huntingtin or Expression of Pathogenic PolyQ Proteins in Drosophila

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849423

Even-skipped, acting as a repressor, regulates axonal projections in Drosophila.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849423

Axon pruning during Drosophila metamorphosis: evidence for local degeneration and requirement of the ubiquitin-proteasome system

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849423

Role of Drosophila Rab5 during endosomal trafficking at the synapse and evoked neurotransmitter release

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849423

Mutations in dynein link motor neuron degeneration to defects in retrograde transport

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849423

Mutant dynactin in motor neuron disease.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849423

Unrestricted synaptic growth in spinster-a late endosomal protein implicated in TGF-beta-mediated synaptic growth regulation.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849423

Disruption of dynein/dynactin inhibits axonal transport in motor neurons causing late-onset progressive degeneration.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849423

A gain-of-function screen for genes controlling motor axon guidance and synaptogenesis in Drosophila

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849423

Gradient formation of the TGF-beta homolog Dpp.

2 September 2018

1 reference

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Single-cell analysis of Drosophila larval neuromuscular synapses

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849423

The fusome organizes the microtubule network during oocyte differentiation in Drosophila.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849423

Drosophila Futsch/22C10 is a MAP1B-like protein required for dendritic and axonal development

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849423

Clonal analysis of Drosophila embryonic neuroblasts: neural cell types, axon projections and muscle targets.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849423

The optically determined size of exo/endo cycling vesicle pool correlates with the quantal content at the neuromuscular junction of Drosophila larvae.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849423

New neuroblast markers and the origin of the aCC/pCC neurons in the Drosophila central nervous system.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849423

Properties of the endosomal-lysosomal system in the human central nervous system: disturbances mark most neurons in populations at risk to degenerate in Alzheimer's disease.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3849423

Two members of the beige/CHS (BEACH) family are involved at different stages in the organization of the endocytic pathway in Dictyostelium

2 September 2018

1 reference

12 December 2020

Ultrastructure of apoptotic oligodendrocytes in the spinal cord of adult rat with long-standing axotomised sciatic nerve

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12 December 2020

A compensatory subpopulation of motor neurons in a mouse model of amyotrophic lateral sclerosis

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12 December 2020

Selective vulnerability and pruning of phasic motoneuron axons in motoneuron disease alleviated by CNTF

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12 December 2020

The neuronal endosomal-lysosomal system in Alzheimer's disease

1 reference

12 December 2020

10.1523/JNEUROSCI.2582-08.2009

Identifiers

DOI

1 reference

19 August 2017

1 reference

19 August 2017

1 reference