Recent advances in DNA vaccines for autoimmune diseases (Q37386307)

20 August 2017

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title

Recent advances in DNA vaccines for autoimmune diseases (English)

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20 August 2017

Celio L Silva

1

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20 August 2017

Vânia Ld Bonato

2

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20 August 2017

Rubens R dos Santos-Júnior

3

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20 August 2017

Carlos R Zárate-Bladés

4

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20 August 2017

Alexandrina Sartori

5

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20 August 2017

1 February 2009

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Expert Review of Vaccines

20 August 2017

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20 August 2017

8

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20 August 2017

2

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20 August 2017

239-252

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Defining the role of the MHC in autoimmunity: a review and pooled analysis

20 August 2017

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https://api.crossref.org/works/10.1586%2F14760584.8.2.239

Mimicking the way to autoimmunity: an evolving theory of sequence and structural homology

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

Presented antigen from damaged pancreatic beta cells activates autoreactive T cells in virus-mediated autoimmune diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

Epidemiological and immunological evidence for the hygiene hypothesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

Parasitic worms and inflammatory diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

Immunoregulation of CNS autoimmunity by helminth and mycobacterial infections.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

The hygiene hypothesis and the increasing prevalence of chronic inflammatory disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

Evolving concepts of rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

Th17 cells and rheumatoid arthritis--from the standpoint of osteoclast differentiation--.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

Effective treatment of collagen-induced arthritis by adoptive transfer of CD25+ regulatory T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

CD25brightCD4+ regulatory T cells are enriched in inflamed joints of patients with chronic rheumatic disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

Advances in type I diabetes associated tolerance mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

Role of regulatory T cells for the treatment of type 1 diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

T regulatory cells in autoimmune diabetes: past challenges, future prospects

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

APC activation restores functional CD4(+)CD25(+) regulatory T cells in NOD mice that can prevent diabetes development

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

Pathogenesis of myelin/oligodendrocyte damage in multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

Multiple sclerosis: immunopathogenesis and controversies in defining the cause

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

The role of regulatory T cells in multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

The 'short' history of regulatory B cells

21 January 2018

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https://api.crossref.org/works/10.1586%2F14760584.8.2.239

T-cell tolerance toward a transgenic beta-cell antigen and transcription of endogenous pancreatic genes in thymus

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

Medullary epithelial cells of the human thymus express a highly diverse selection of tissue-specific genes colocalized in chromosomal clusters

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

Receptor editing in lymphocyte development and central tolerance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

Regulatory T-cell immunotherapy for tolerance to self antigens and alloantigens in humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

Functional features of human CD25+ regulatory thymocytes

21 January 2018

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https://api.crossref.org/works/10.1586%2F14760584.8.2.239

Development of regulatory T cells requires IL-7Ralpha stimulation by IL-7 or TSLP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

Control of regulatory T cell development by the transcription factor Foxp3

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

An essential role for Scurfin in CD4+CD25+ T regulatory cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

Is FOXP3 a bona fide marker for human regulatory T cells?

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-beta and retinoic acid-dependent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

CD8+ CD205+ splenic dendritic cells are specialized to induce Foxp3+ regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

TGF-beta and CD4+CD25+ regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

Mechanisms of regulatory T-cell suppression - a diverse arsenal for a moving target

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

Adenosine and cAMP are potent inhibitors of the NF-kappa B pathway downstream of immunoreceptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

A critical role for transforming growth factor-beta but not interleukin 4 in the suppression of T helper type 1-mediated colitis by CD45RB(low) CD4+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

CD4+CD25+Foxp3+ regulatory T cells induce cytokine deprivation-mediated apoptosis of effector CD4+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

Antigen-specific tolerance strategies for the prevention and treatment of autoimmune disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

The Institut Pasteur: 120years of research in microbiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

Direct gene transfer into mouse muscle in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

Heterologous protection against influenza by injection of DNA encoding a viral protein

21 January 2018

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https://api.crossref.org/works/10.1586%2F14760584.8.2.239

From plasmids to protection: a review of DNA vaccines against infectious diseases

21 January 2018

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https://api.crossref.org/works/10.1586%2F14760584.8.2.239

Protection against tuberculosis by a plasmid DNA vaccine.

21 January 2018

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https://api.crossref.org/works/10.1586%2F14760584.8.2.239

Therapy of tuberculosis in mice by DNA vaccination.

21 January 2018

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https://api.crossref.org/works/10.1586%2F14760584.8.2.239

DNA vaccines: ready for prime time?

21 January 2018

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https://api.crossref.org/works/10.1586%2F14760584.8.2.239

Current progress of DNA vaccine studies in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

Uptake and trafficking of DNA in keratinocytes: evidence for DNA-binding proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

Role of scavenger receptor MARCO in macrophage responses to CpG oligodeoxynucleotides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

Endocytosis of DNA-Hsp65 alters the pH of the late endosome/lysosome and interferes with antigen presentation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

Intracellular routing of plasmid DNA during non-viral gene transfer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

Nucleocytoplasmic transport of plasmid DNA: a perilous journey from the cytoplasm to the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

DNA vaccines: are they still just a powerful tool for the future?

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

A Toll-like receptor recognizes bacterial DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

TLR9 signals after translocating from the ER to CpG DNA in the lysosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

Immune cell activation by bacterial CpG-DNA through myeloid differentiation marker 88 and tumor necrosis factor receptor-associated factor (TRAF)6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

CpG ODN-mediated regulation of IL-12 p40 transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

Cutting edge: a novel Toll/IL-1 receptor domain-containing adapter that preferentially activates the IFN-beta promoter in the Toll-like receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

CpG motifs in bacterial DNA trigger direct B-cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

Modulation of Toll-like Receptor 9 Responses through Synthetic Immunostimulatory Motifs of DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

A DNA vaccine against tuberculosis based on the 65 kDa heat-shock protein differentially activates human macrophages and dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

Physiologic regulation of central and peripheral T cell tolerance: lessons for therapeutic applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

DNA vaccination with CD25 protects rats from adjuvant arthritis and induces an antiergotypic response

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

Immunoregulation of autoimmunity by natural killer T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

Interplay between effector Th17 and regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

Therapeutic benefits of regulating inflammation in autoimmunity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

Gene vaccination for the induction of immune tolerance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

Vaccination against self to prevent autoimmune disease: the type 1 diabetes model

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

DNA vaccination with heat shock protein 60 inhibits cyclophosphamide-accelerated diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

Regulatory T cells and human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

Cooperative roles of CTLA-4 and regulatory T cells in tolerance to an islet cell antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

Co-delivery of pro-apoptotic BAX with a DNA vaccine recruits dendritic cells and promotes efficacy of autoimmune diabetes prevention in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

21 January 2018

The heat-shock response

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

ER-60, a chaperone with thiol-dependent reductase activity involved in MHC class I assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

Activation of T cells recognizing self 60-kD heat shock protein can protect against experimental arthritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

NOD mouse diabetes: the ubiquitous mouse hsp60 is a beta-cell target antigen of autoimmune T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

Heat shock proteins and experimental autoimmune encephalomyelitis. II: environmental infection and extra-neuraxial inflammation alter the course of chronic relapsing encephalomyelitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

Modulation of pristane-induced arthritis by mycobacterial antigens

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

Heat shock proteins induce T cell regulation of chronic inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

Immunoregulation of autoimmune diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

Hsp90 binds CpG oligonucleotides directly: implications for hsp90 as a missing link in CpG signaling and recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

Tumor cells transfected with a bacterial heat-shock gene lose tumorigenicity and induce protection against tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

Heat shock proteins: biological functions and clinical application as personalized vaccines for human cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

Sequence homologies between hsp60 and autoantigens

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

Cross-reactive B-cell epitopes of microbial and human heat shock protein 60/65 in atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

Methylated CpG-containing plasmid activates the immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

From bugs to drugs: therapeutic immunomodulation with oligodeoxynucleotides containing CpG sequences from bacterial DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

Targeting the innate immune response with improved vaccine adjuvants

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

Sequence motifs in adenoviral DNA block immune activation by stimulatory CpG motifs

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

Inhibition of murine macrophage IL-12 production by natural and synthetic DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

Identification of methylated CpG motifs as inhibitors of the immune stimulatory CpG motifs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

DNA vaccination with an insulin construct and a chimeric protein binding to both CTLA4 and CD40 ameliorates type 1 diabetes in NOD mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

Immunoinhibitory DNA vaccine protects against autoimmune diabetes through cDNA encoding a selective CTLA-4 (CD152) ligand.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

A targeted DNA vaccine encoding fas ligand defines its dual role in the regulation of experimental autoimmune encephalomyelitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

Safety and efficacy of vaccination against hepatitis B in patients with rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

TNFalpha DNA vaccination prevents clinical manifestations of experimental antiphospholipid syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

Augmentation of natural immunity to a pro-inflammatory cytokine (TNF-alpha) by targeted DNA vaccine confers long-lasting resistance to experimental autoimmune encephalomyelitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

Phase 2 trial of a DNA vaccine encoding myelin basic protein for multiple sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

Phase I trial of DNA-hsp65 immunotherapy for advanced squamous cell carcinoma of the head and neck

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

TANK-binding kinase-1 delineates innate and adaptive immune responses to DNA vaccines

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

Protein microarrays guide tolerizing DNA vaccine treatment of autoimmune encephalomyelitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

Induction of antigen-specific tolerance in multiple sclerosis after immunization with DNA encoding myelin basic protein in a randomized, placebo-controlled phase 1/2 trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14760584.8.2.239

21 January 2018

Identifiers

DOI

10.1586/14760584.8.2.239

1 reference

20 August 2017

1 reference