Phosphorylation of microtubule-binding protein Hec1 by mitotic kinase Aurora B specifies spindle checkpoint kinase Mps1 signaling at the kinetochore. (Q37388868)

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English	Phosphorylation of microtubule-binding protein Hec1 by mitotic kinase Aurora B specifies spindle checkpoint kinase Mps1 signaling at the kinetochore.	scientific article

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29 February 2020

Phosphorylation of microtubule-binding protein Hec1 by mitotic kinase Aurora B specifies spindle checkpoint kinase Mps1 signaling at the kinetochore (English)

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29 February 2020

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29 February 2020

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Tongge Zhu

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Bo Qin

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Changjiang Jin

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29 February 2020

Xinghui Wang

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Leilei Xu

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Zhaoyang Wang

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Lijuan Zhu

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29 February 2020

Fusheng Liu

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29 February 2020

Xinjiao Gao

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29 February 2020

Yuwen Ke

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29 February 2020

Zhiyong Wang

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29 February 2020

Felix Aikhionbare

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29 February 2020

Xia Ding

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29 February 2020

Xuebiao Yao

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1 November 2013

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29 February 2020

Journal of Biological Chemistry

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29 February 2020

36149-36159

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29 February 2020

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A TPR domain–containing N-terminal module of MPS1 is required for its kinetochore localization by Aurora B

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3861662

6 September 2017

Microtubule attachment and spindle assembly checkpoint signalling at the kinetochore

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3861662

6 September 2017

Mitotic regulator SKAP forms a link between kinetochore core complex KMN and dynamic spindle microtubules

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3861662

6 September 2017

The MPS1 family of protein kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3861662

6 September 2017

Structure of the mitotic checkpoint complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3861662

6 September 2017

Molecular architecture of vertebrate kinetochores

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3861662

6 September 2017

CENP-E kinesin interacts with SKAP protein to orchestrate accurate chromosome segregation in mitosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3861662

6 September 2017

Spindle checkpoint silencing: PP1 tips the balance.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3861662

6 September 2017

Probing the in vivo function of Mad1:C-Mad2 in the spindle assembly checkpoint

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3861662

6 September 2017

Quantitative mass spectrometry analysis reveals similar substrate consensus motif for human Mps1 kinase and Plk1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3861662

6 September 2017

Evidence that Aurora B is implicated in spindle checkpoint signalling independently of error correction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3861662

6 September 2017

Temporal changes in Hec1 phosphorylation control kinetochore-microtubule attachment stability during mitosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3861662

6 September 2017

Probing CENP-E function in chromosome dynamics using small molecule inhibitor syntelin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3861662

6 September 2017

Sensing centromere tension: Aurora B and the regulation of kinetochore function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3861662

6 September 2017

CENP-U cooperates with Hec1 to orchestrate kinetochore-microtubule attachment.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3861662

6 September 2017

Aurora B kinase controls the targeting of the Astrin-SKAP complex to bioriented kinetochores.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3861662

6 September 2017

Dissecting the role of MPS1 in chromosome biorientation and the spindle checkpoint through the small molecule inhibitor reversine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3861662

6 September 2017

Aurora B phosphorylates spatially distinct targets to differentially regulate the kinetochore-microtubule interface

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3861662

6 September 2017

Protein architecture of the human kinetochore microtubule attachment site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3861662

6 September 2017

Sensing chromosome bi-orientation by spatial separation of aurora B kinase from kinetochore substrates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3861662

6 September 2017

Kinetochore-microtubule attachment relies on the disordered N-terminal tail domain of Hec1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3861662

6 September 2017

Phosphorylation of HsMis13 by Aurora B kinase is essential for assembly of functional kinetochore

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3861662

6 September 2017

Implications for kinetochore-microtubule attachment from the structure of an engineered Ndc80 complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3861662

6 September 2017

The mitotic checkpoint kinase NEK2A regulates kinetochore microtubule attachment stability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3861662

6 September 2017

Cdc20: a WD40 activator for a cell cycle degradation machine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3861662

6 September 2017

Human NUF2 interacts with centromere-associated protein E and is essential for a stable spindle microtubule-kinetochore attachment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3861662

6 September 2017

The spindle-assembly checkpoint in space and time

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3861662

6 September 2017

The Ndc80/HEC1 complex is a contact point for kinetochore-microtubule attachment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3861662

6 September 2017

The conserved KMN network constitutes the core microtubule-binding site of the kinetochore

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3861662

6 September 2017

Kinetochore microtubule dynamics and attachment stability are regulated by Hec1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3861662

6 September 2017

Molecular organization of the Ndc80 complex, an essential kinetochore component

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3861662

6 September 2017

A conserved protein network controls assembly of the outer kinetochore and its ability to sustain tension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3861662

6 September 2017

Germ cell aneuploidy in zebrafish with mutations in the mitotic checkpoint gene mps1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3861662

6 September 2017

Bub1 is required for kinetochore localization of BubR1, Cenp-E, Cenp-F and Mad2, and chromosome congression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3861662

6 September 2017

Nuf2 and Hec1 are required for retention of the checkpoint proteins Mad1 and Mad2 to kinetochores

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3861662

6 September 2017

Aurora B couples chromosome alignment with anaphase by targeting BubR1, Mad2, and Cenp-E to kinetochores

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3861662

6 September 2017

Human MPS1 kinase is required for mitotic arrest induced by the loss of CENP-E from kinetochores

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3861662

6 September 2017

Role of Hec1 in spindle checkpoint signaling and kinetochore recruitment of Mad1/Mad2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3861662

6 September 2017

Human Mps1 kinase is required for the spindle assembly checkpoint but not for centrosome duplication

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3861662

6 September 2017

Checkpoint inhibition of the APC/C in HeLa cells is mediated by a complex of BUBR1, BUB3, CDC20, and MAD2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3861662

6 September 2017

The microtubule-dependent motor centromere-associated protein E (CENP-E) is an integral component of kinetochore corona fibers that link centromeres to spindle microtubules.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3861662

6 September 2017

HEC, a novel nuclear protein rich in leucine heptad repeats specifically involved in mitosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3861662

6 September 2017

Activation of the budding yeast spindle assembly checkpoint without mitotic spindle disruption.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3861662

6 September 2017

Aurora B potentiates Mps1 activation to ensure rapid checkpoint establishment at the onset of mitosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3861662

6 September 2017

Mph1, a member of the Mps1-like family of dual specificity protein kinases, is required for the spindle checkpoint in S. pombe.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3861662

26 June 2018

Mad2 "opens" Cdc20 for BubR1 binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3861662

2 September 2018

Catalytic assembly of the mitotic checkpoint inhibitor BubR1-Cdc20 by a Mad2-induced functional switch in Cdc20.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3861662

2 September 2018

The mitotic arrest in response to hypoxia and of polar bodies during early embryogenesis requires Drosophila Mps1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3861662

2 September 2018

Mps1 is a kinetochore-associated kinase essential for the vertebrate mitotic checkpoint.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3861662

2 September 2018

Dynamic distribution of TTK in HeLa cells: insights from an ultrastructural study

1 reference

https://pubmed.ncbi.nlm.nih.gov/24187132

12 December 2020

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29 February 2020

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